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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 20, 2017 - Issue 7
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Original Articles

Effects of β-hydroxy-β-methyl butyrate on working memory and cognitive flexibility in an animal model of aging

Emily R. HankoskyDepartment of Psychology, University of Illinois, Urbana–Champaign, USA
,
Luke K. SherrillDepartment of Psychology, University of Illinois, Urbana–Champaign, USA
,
Lauren A. RuvolaDepartment of Psychology, University of Illinois, Urbana–Champaign, USA
,
Rachel M. HaakeDepartment of Psychology, University of Illinois, Urbana–Champaign, USA
,
Taehyeon KimDepartment of Psychology, University of Illinois, Urbana–Champaign, USA
,
Lindsey R. HammerslagNeuroscience Program, University of Illinois, Urbana–Champaign, USA
,
Daniel G. KougiasNeuroscience Program, University of Illinois, Urbana–Champaign, USA
,
Janice M. JuraskaDepartment of Psychology, University of Illinois, Urbana–Champaign, USA;Neuroscience Program, University of Illinois, Urbana–Champaign, USA
&
Joshua M. GulleyDepartment of Psychology, University of Illinois, Urbana–Champaign, USA;Neuroscience Program, University of Illinois, Urbana–Champaign, USACorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-3929-8791
ORCID Icon show all
Pages 379-387 | Published online: 19 Feb 2016

Citations (16)

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Michael Munroe, Ziad S. Mahmassani, Svyatoslav Dvoretskiy, Justin J. Reid, Benjamin F. Miller, Karyn Hamilton, Justin S. Rhodes & Marni D. Boppart. (2020) Cognitive function is preserved in aged mice following long-term β-hydroxy β-methylbutyrate supplementation. Nutritional Neuroscience 23:3, pages 170-182.
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Articles from other publishers (15)

Lauren K. Carrica, Chan Young Choi, Francis A. Walter, Brynn L. Noonan, Linyuan Shi, Clare T. Johnson, Heather B. Bradshaw, Nu-Chu Liang & Joshua M. Gulley. (2023) Effects of combined use of alcohol and delta-9-tetrahydrocannibinol on working memory in Long Evans rats. Behavioural Brain Research 449, pages 114475.
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Matteo Tosato, Francesca Ciciarello, Maria Beatrice Zazzara, Cristina Pais, Giulia Savera, Anna Picca, Vincenzo Galluzzo, Hélio José Coelho-Júnior, Riccardo Calvani, Emanuele Marzetti & Francesco Landi. (2022) Nutraceuticals and Dietary Supplements for Older Adults with Long COVID-19. Clinics in Geriatric Medicine 38:3, pages 565-591.
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Mariëlle P.K.J. Engelen. (2022) Editorial: The role of targeted nutritional modulation alongside exercise rehabilitation to improve systemic health outcomes in chronic diseases. Current Opinion in Clinical Nutrition & Metabolic Care 25:3, pages 133-135.
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Alejandro Barranco, Llenalia Garcia, Agnes Gruart, Jose Maria Delgado-Garcia, Ricardo Rueda & Maria Ramirez. (2022) Effects of β-Hydroxy β-Methylbutyrate Supplementation on Working Memory and Hippocampal Long-Term Potentiation in Rodents. Nutrients 14:5, pages 1090.
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Ewa Tomaszewska, Siemowit Muszyński, Janine Donaldson, Piotr Dobrowolski, Deepesh K. P. Chand, Agnieszka Tomczyk-Warunek, Monika Hułas-Stasiak, Iwona Puzio, Krzysztof Lamorski, Cezary Sławiński, Mirosław Jabłoński & Tomasz Blicharski. (2021) Femoral µCT Analysis, Mechanical Testing and Immunolocalization of Bone Proteins in β-Hydroxy β-Methylbutyrate (HMB) Supplemented Spiny Mouse in a Model of Pregnancy and Lactation-Associated Osteoporosis. Journal of Clinical Medicine 10:21, pages 4808.
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Julien Schmitt, Anne-Lise Paradis, Mathieu Boucher, Laurent Andrieu, Pascal Barnéoud & Laure Rondi-Reig. (2021) Flexibility as a marker of early cognitive decline in humanized apolipoprotein E ε4 (ApoE4) mice. Neurobiology of Aging 102, pages 129-138.
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Ewa Tomaszewska, Janine Donaldson, Jakub Kosiński, Piotr Dobrowolski, Agnieszka Tomczyk-Warunek, Monika Hułas-Stasiak, Krzysztof Lamorski, Dorota Laskowska-Woźniak, Siemowit Muszyński, Rudolf Blicharski & Tomasz Blicharski. (2021) β-Hydroxy-β-Methylbutyrate (HMB) Supplementation Prevents Bone Loss during Pregnancy—Novel Evidence from a Spiny Mouse (Acomys cahirinus) Model. International Journal of Molecular Sciences 22:6, pages 3047.
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Amogh Belagodu, Shuo Kang, Joshua M. Gulley & Roberto Galvez. 2021. Factors Affecting Neurological Aging. Factors Affecting Neurological Aging 627 636 .
Javier Courel-Ibáñez & JG Pallarés. (2019) Effects of β-hydroxy-β-methylbutyrate (HMB) supplementation in addition to multicomponent exercise in adults older than 70 years living in nursing homes, a cluster randomized placebo-controlled trial: the HEAL study protocol. BMC Geriatrics 19:1.
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Courel-Ibáñez, Vetrovsky, Dadova, Pallarés & Steffl. (2019) Health Benefits of β-Hydroxy-β-Methylbutyrate (HMB) Supplementation in Addition to Physical Exercise in Older Adults: A Systematic Review with Meta-Analysis. Nutrients 11:9, pages 2082.
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Mariëlle P.K.J. Engelen & Nicolaas E.P. Deutz. (2018) Is β-hydroxy β-methylbutyrate an effective anabolic agent to improve outcome in older diseased populations?. Current Opinion in Clinical Nutrition & Metabolic Care 21:3, pages 207-213.
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Daniel G. Kougias, Tapas Das, Alejandro Barranco Perez & Suzette L. Pereira. (2018) A role for nutritional intervention in addressing the aging neuromuscular junction. Nutrition Research 53, pages 1-14.
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Milan Holeček. (2017) Beta-hydroxy-beta-methylbutyrate supplementation and skeletal muscle in healthy and muscle-wasting conditions. Journal of Cachexia, Sarcopenia and Muscle 8:4, pages 529-541.
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Daniel G. Kougias, Emily R. Hankosky, Joshua M. Gulley & Janice M. Juraska. (2017) Beta-hydroxy-beta-methylbutyrate (HMB) ameliorates age-related deficits in water maze performance, especially in male rats. Physiology & Behavior 170, pages 93-99.
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Michael Munroe, Yair Pincu, Jennifer Merritt, Adam Cobert, Ryan Brander, Tor Jensen, Justin Rhodes & Marni D. Boppart. (2017) Impact of β-hydroxy β-methylbutyrate (HMB) on age-related functional deficits in mice. Experimental Gerontology 87, pages 57-66.
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