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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 22, 2019 - Issue 5
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Short-term and long-term efficacy of classical ketogenic diet and modified Atkins diet in children and adolescents with epilepsy: A systematic review and meta-analysis

Shahabeddin RezaeiDepartment of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran;Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
,
Ahmed Abdulahi AbdurahmanDepartment of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences International Campus (TUMS-IC), Tehran, Iran
,
Amene SaghazadehMolecular Immunology Research Center, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran;Systematic Review and Meta-analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, Iran
,
Reza Shervin BadvPaediatrics Centre of Excellence, Department of Paediatric Neurology, Children’s Medical Centre, Tehran University of Medical Sciences, Tehran, Iran
&
Maryam MahmoudiDepartment of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran;Pediatric Gastroenterology and Hepatology Research Center, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran;Dietitians and Nutrition Experts Team (DiNET), Universal Scientific Education and Research Network (USERN), Tehran, IranCorrespondence[email protected] [email protected]
Pages 317-334 | Published online: 25 Oct 2017

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Ebru Cicek & Nevin Sanlier. (2023) The place of a ketogenic diet in the treatment of resistant epilepsy: a comprehensive review. Nutritional Neuroscience 26:9, pages 828-841.
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Cristina Díez-Arroyo, Mónica García-García, María José Soto-Méndez, Esther Molina-Montes, Mercedes Gil-Campos, Ángel Gil, Miriam Gutiérrez-Jimeno & Ángela Hernández-Ruiz. (2023) Effect of the ketogenic diet as a treatment for refractory epilepsy in children and adolescents: a systematic review of reviews. Nutrition Reviews.
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M. Yu. Bobylova, E. I. Novyachkova, K. S. Romanovskaya, L. N. Mukhina & K. Yu. Mukhin. (2023) The role of the ketogenic diet in patients with epilepsy. A brief literary review and a clinical example. Russian Journal of Child Neurology 18:1, pages 57-64.
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Mala ManralRekha DwivediSheffali GulatiKirandeep KaurAshima NehraRavindra Mohan PandeyAshish Datt UpadhyaySavita SapraManjari Tripathi. (2023) Safety, Efficacy, and Tolerability of Modified Atkins Diet in Persons With Drug-Resistant Epilepsy. Neurology 100:13.
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Mario Mastrangelo, Dario Esposito, Sabrina De Leo & Federica Gigliotti. 2023. Diet and Nutrition in Neurological Disorders. Diet and Nutrition in Neurological Disorders 471 490 .
Rowena Field, Tara Field, Fereshteh Pourkazemi & Kieron Rooney. (2021) Ketogenic diets and the nervous system: a scoping review of neurological outcomes from nutritional ketosis in animal studies. Nutrition Research Reviews 35:2, pages 268-281.
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Damian Dyńka, Katarzyna Kowalcze & Agnieszka Paziewska. (2022) The Role of Ketogenic Diet in the Treatment of Neurological Diseases. Nutrients 14:23, pages 5003.
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Urszula Skrobas, Piotr Duda, Łukasz Bryliński, Paulina Drożak, Magdalena Pelczar & Konrad Rejdak. (2022) Ketogenic Diets in the Management of Lennox-Gastaut Syndrome—Review of Literature. Nutrients 14:23, pages 4977.
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Naim Tayutivutikul, Pitchaya Wanleenuwat, Thanaphat Panapongvasin, Rakklao Klajing & Piotr Iwanowski. (2022) Dietary effects on antiseizure drug metabolism and management of epilepsy. Seizure: European Journal of Epilepsy 102, pages 14-21.
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Asmaa Mhanna, Mohammed Mhanna, Azizullah Beran, Mustafa Al-Chalabi, Nameer Aladamat & Naeem Mahfooz. (2022) Modified Atkins diet versus ketogenic diet in children with drug-resistant epilepsy: A meta-analysis of comparative studies. Clinical Nutrition ESPEN 51, pages 112-119.
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Yue Ruan, Lian Chen, Dongli She, Yuehuan Chung, Long Ge & Lin Han. (2022) Ketogenic diet for epilepsy: an overview of systematic review and meta-analysis. European Journal of Clinical Nutrition 76:9, pages 1234-1244.
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Fatemeh Madani, Seyedeh Sara Esnaashari, Thomas J. Webster, Masood Khosravani & Mahdi Adabi. (2022) Polymeric nanoparticles for drug delivery in glioblastoma: State of the art and future perspectives. Journal of Controlled Release 349, pages 649-661.
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Tyler Vaivada, Naeha Sharma, Jai K. Das, Rehana A. Salam, Zohra S. Lassi & Zulfiqar A. Bhutta. (2022) Interventions for Health and Well-Being in School-Aged Children and Adolescents: A Way Forward. Pediatrics 149:Supplement 6.
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Reena P Jain, Daina Als, Tyler Vaivada & Zulfiqar A Bhutta. (2022) Prevention and Management of High-Burden Noncommunicable Diseases in School-Age Children: A Systematic Review. Pediatrics 149:Supplement 6.
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Rowena J Field, Tara J Field, Fereshteh Pourkazemi & Kieron B Rooney. (2022) Experience of participants with chronic pain in a pilot randomized clinical trial using a ketogenic diet. Pain Management 12:3, pages 313-322.
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Hayat Alameen Ali, Osama Muthaffar, Nahla AlKarim, Husam Kayyali, Ahmed Elmardenly, Abdullah Tamim & Hala Alansari. (2022) The efficacy of non-fasting ketogenic diet protocol in the management of intractable epilepsy in pediatric patients: a single center study from Saudi Arabia. Journal of International Medical Research 50:3, pages 030006052210817.
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Lauren Pickel, Ioan-Andrei Iliuta, James Scholey, York Pei & Hoon-Ki Sung. (2022) Dietary Interventions in Autosomal Dominant Polycystic Kidney Disease. Advances in Nutrition 13:2, pages 652-666.
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Katharina Schiller, Tamir Avigdor, Aline Kortas, Mirjam Kunz, Gabriele Unterholzner, Martin Klingelhöfer & Markus Rauchenzauner. (2022) Monitoring Glucose Concentrations in Children with Epilepsy on a Ketogenic Diet. Healthcare 10:2, pages 245.
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Rongrong Yang, Jialun Wen, Wenjing Wei, Haili Chen, Dezhi Cao, Li Chen, Xinguo Lu, Yan Hu, Tieshuan Huang, Bing Li, Sufang Lin, Dongfang Zou, Jinghua Ye, Man Zhang, Yaoye Wang, Mei Yu, Jianxiang Liao & Zhitian Xiao. (2022) Improving the effects of ketogenic diet therapy in children with drug-resistant epilepsy. Seizure 94, pages 183-188.
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Anna-Maria Costa, Maddalena Marchiò, Giulia Bruni, Silvia Maria Bernabei, Silvia Cavalieri, Marina Bondi & Giuseppe Biagini. (2021) Evaluation of E-Health Applications for Paediatric Patients with Refractory Epilepsy and Maintained on Ketogenic Diet. Nutrients 13:4, pages 1240.
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Alberto Verrotti, Giulia Iapadre, Ludovica Di Francesco, Luca Zagaroli & Giovanni Farello. (2020) Diet in the Treatment of Epilepsy: What We Know So Far. Nutrients 12:9, pages 2645.
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Jonathan J. Halford & Jonathan C. Edwards. (2020) Seizure freedom as an outcome in epilepsy treatment clinical trials. Acta Neurologica Scandinavica 142:2, pages 91-107.
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Faleh Alqahtani, Imran Imran, Hafsa Pervaiz, Waseem Ashraf, Nadia Perveen, Muhammad Fawad Rasool, Abdullah F. Alasmari, Metab Alharbi, Noreen Samad, Saleh Abdullah Alqarni, Salim S. Al-Rejaie & Mohammed Mufadhe Alanazi. (2020) Non-pharmacological Interventions for Intractable Epilepsy. Saudi Pharmaceutical Journal 28:8, pages 951-962.
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Jana Wells, Arun Swaminathan, Jenna Paseka & Corrine Hanson. (2020) Efficacy and Safety of a Ketogenic Diet in Children and Adolescents with Refractory Epilepsy—A Review. Nutrients 12:6, pages 1809.
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Jo Sourbron, Sylvia Klinkenberg, Sander M. J. van Kuijk, Lieven Lagae, Danielle Lambrechts, Hilde M. H. Braakman & Marian Majoie. (2020) Ketogenic diet for the treatment of pediatric epilepsy: review and meta-analysis. Child's Nervous System 36:6, pages 1099-1109.
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Un Ju Jung & Sang Ryong Kim. (2020) Reply to M. Heidari and S. Rezaei. Advances in Nutrition 11:3, pages 742.
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Morteza Heidari & Shahabeddin Rezaei. (2020) Letter to the Editor on “Perspective: Therapeutic Potential of Flavonoids as Alternative Medicines in Epilepsy”. Advances in Nutrition 11:3, pages 741.
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Amene Saghazadeh, Maryam Mahmoudi, Shayan Shahrokhi, Maryam Mojarrad, Maedeh Dastmardi, Mona Mirbeyk & Nima Rezaei. (2020) Trace elements in schizophrenia: a systematic review and meta-analysis of 39 studies (N = 5151 participants). Nutrition Reviews 78:4, pages 278-303.
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Saša Kenig, Ana Petelin, Tamara Poklar Vatovec, Nina Mohorko & Zala Jenko-Pražnikar. (2019) Assessment of micronutrients in a 12-wk ketogenic diet in obese adults. Nutrition 67-68, pages 110522.
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Marzena Ułamek-Kozioł, Stanisław J. Czuczwar, Sławomir Januszewski & Ryszard Pluta. (2019) Ketogenic Diet and Epilepsy. Nutrients 11:10, pages 2510.
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Sean T. Hwang, Scott J. Stevens, Aradia X. Fu & Simona V. Proteasa. (2019) Intractable Generalized Epilepsy: Therapeutic Approaches. Current Neurology and Neuroscience Reports 19:4.
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Isabella D’Andrea Meira, Tayla Taynan Romão, Henrique Jannuzzelli Pires do Prado, Lia Theophilo Krüger, Maria Elisa Paiva Pires & Priscila Oliveira da Conceição. (2019) Ketogenic Diet and Epilepsy: What We Know So Far. Frontiers in Neuroscience 13.
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Shahabeddin Rezaei, Sara Harsini, Mona Kavoosi, Reza Shervin Badv & Maryam Mahmoudi. (2018) Efficacy of low glycemic index treatment in epileptic patients: a systematic review. Acta Neurologica Belgica 118:3, pages 339-349.
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