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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 22, 2019 - Issue 12
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Articles

Intragastric quinine administration decreases hedonic eating in healthy women through peptide-mediated gut-brain signaling mechanisms

Julie IvenLaboratory for Brain-Gut Axis Studies (LaBGAS), Translational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven, Belgium
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Jessica R. BiesiekierskiLaboratory for Brain-Gut Axis Studies (LaBGAS), Translational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven, Belgium
,
Dongxing ZhaoLaboratory for Brain-Gut Axis Studies (LaBGAS), Translational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven, Belgium
,
Eveline DelooseLaboratory for Brain-Gut Axis Studies (LaBGAS), Translational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven, BelgiumORCID Iconhttps://orcid.org/0000-0001-8694-7745
ORCID Icon,
Owen G. O’DalyCenter for Neuroimaging Sciences, Psychology, and Neurosciences, Institute of Psychiatry, King’s College London, London, UK
,
Inge DepoortereLaboratory for Brain-Gut Axis Studies (LaBGAS), Translational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven, BelgiumORCID Iconhttps://orcid.org/0000-0002-0289-2175
ORCID Icon,
Jan TackLaboratory for Brain-Gut Axis Studies (LaBGAS), Translational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven, BelgiumORCID Iconhttps://orcid.org/0000-0002-3206-6704
ORCID Icon &
Lukas Van OudenhoveLaboratory for Brain-Gut Axis Studies (LaBGAS), Translational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven, BelgiumCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-6540-3113
ORCID Icon show all
Pages 850-862 | Published online: 02 Apr 2018

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Julie Iven, Jessica R. Biesiekierski, Dongxing Zhao, Jan Tack & Lukas Van Oudenhove. (2022) Intragastric fructose administration interacts with emotional state in homeostatic and hedonic brain regions. Nutritional Neuroscience 25:3, pages 581-592.
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Articles from other publishers (28)

Peyman Rezaie, Vida Bitarafan, Braden David Rose, Kylie Lange, Zinat Mohammadpour, Jens Frederik Rehfeld, Michael Horowitz & Christine Feinle-Bisset. (2023) Effects of Quinine on the Glycaemic Response to, and Gastric Emptying of, a Mixed-Nutrient Drink in Females and Males. Nutrients 15:16, pages 3584.
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Amy S. Graham, Benneth Ben-Azu, Marie-Ève Tremblay, Peter TorreIIIIII, Marjanne Senekal, Barbara Laughton, Andre van der Kouwe, Marcin Jankiewicz, Mamadou Kaba & Martha J. Holmes. (2023) A review of the auditory-gut-brain axis. Frontiers in Neuroscience 17.
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Corinna Schulz, Cecilia Vezzani & Nils B. Kroemer. (2023) How gut hormones shape reward: A systematic review of the role of ghrelin and GLP-1 in human fMRI. Physiology & Behavior 263, pages 114111.
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Hideki Mori, Wout Verbeure, Rina Tanemoto, Emily Ruilova Sosoranga & Jan Tack. (2023) Physiological functions and potential clinical applications of motilin. Peptides 160, pages 170905.
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Luke Hassan, Lisa Newman, Russell Keast, Jessica Danaher & Jessica R. Biesiekierski. (2023) The effect of gastrointestinal bitter sensing on appetite regulation and energy intake: A systematic review. Appetite 180, pages 106336.
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Andreas G. Niethammer, Zhenhuan Zheng, Anjuli Timmer & Tien‐Li Lee. (2022) First‐in‐Human Evaluation of Oral Denatonium Acetate (ARD‐101), a Potential Bitter Taste Receptor Agonist: A Randomized, Double‐Blind, Placebo‐Controlled Phase 1 Trial in Healthy Adults. Clinical Pharmacology in Drug Development 11:8, pages 997-1006.
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Peyman Rezaie, Vida Bitarafan, Braden D Rose, Kylie Lange, Jens F Rehfeld, Michael Horowitz & Christine Feinle-Bisset. (2022) Quinine Effects on Gut and Pancreatic Hormones and Antropyloroduodenal Pressures in Humans–Role of Delivery Site and Sex. The Journal of Clinical Endocrinology & Metabolism 107:7, pages e2870-e2881.
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Edward G Walker, Kim R Lo, Malcolm C Pahl, Hyun S Shin, Claudia Lang, Mark W Wohlers, Sally D Poppitt, Kevin H Sutton & John R Ingram. (2022) An extract of hops (Humulus lupulus L.) modulates gut peptide hormone secretion and reduces energy intake in healthy-weight men: a randomized, crossover clinical trial. The American Journal of Clinical Nutrition 115:3, pages 925-940.
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Kamila Tuzim & Agnieszka Korolczuk. (2021) An update on extra-oral bitter taste receptors. Journal of Translational Medicine 19:1.
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Tim Klaassen, Daniel Keszthelyi, Freddy J. Troost, Aalt Bast & Adrian A. M. Masclee. (2021) Effects of gastrointestinal delivery of non-caloric tastants on energy intake: a systematic review and meta-analysis. European Journal of Nutrition 60:6, pages 2923-2947.
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Wout Verbeure, Eveline Deloose, Joran Tóth, Jens F. Rehfeld, Lukas Van Oudenhove, Inge Depoortere & Jan Tack. (2021) The endocrine effects of bitter tastant administration in the gastrointestinal system: intragastric versus intraduodenal administration. American Journal of Physiology-Endocrinology and Metabolism 321:1, pages E1-E10.
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Jan Tack, Wout Verbeure, Hideki Mori, Jolien Schol, Karen Van den Houte, I‐Hsuan Huang, Lukas Balsiger, Bert Broeders, Esther Colomier, Emidio Scarpellini & Florencia Carbone. (2021) The gastrointestinal tract in hunger and satiety signalling. United European Gastroenterology Journal 9:6, pages 727-734.
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Braden D Rose, Vida Bitarafan, Peyman Rezaie, Penelope C E Fitzgerald, Michael Horowitz & Christine Feinle-Bisset. (2021) Comparative Effects of Intragastric and Intraduodenal Administration of Quinine on the Plasma Glucose Response to a Mixed-Nutrient Drink in Healthy Men: Relations with Glucoregulatory Hormones and Gastric Emptying. The Journal of Nutrition 151:6, pages 1453-1461.
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Jennifer Wilbrink, Gwen Masclee, Tim Klaassen, Mark van Avesaat, Daniel Keszthelyi & Adrian Masclee. (2021) Review on the Regional Effects of Gastrointestinal Luminal Stimulation on Appetite and Energy Intake: (Pre)clinical Observations. Nutrients 13:5, pages 1601.
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Peyman Rezaie, Vida Bitarafan, Michael Horowitz & Christine Feinle-Bisset. (2021) Effects of Bitter Substances on GI Function, Energy Intake and Glycaemia-Do Preclinical Findings Translate to Outcomes in Humans?. Nutrients 13:4, pages 1317.
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Caroline P Harmon, Daiyong Deng & Paul AS Breslin. (2021) Bitter taste receptors (T2Rs) are sentinels that coordinate metabolic and immunological defense responses. Current Opinion in Physiology 20, pages 70-76.
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Maria Nunez‐Salces, Hui Li, Christine Feinle‐Bisset, Richard L. Young & Amanda J. Page. (2020) The regulation of gastric ghrelin secretion. Acta Physiologica 231:3.
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Tim Klaassen, Daniel Keszthelyi, Annick M. E. Alleleyn, Ellen Wilms, Aalt Bast, Adrian A. M. Masclee & Freddy J. Troost. (2020) Effect of oral or intragastric delivery of the bitter tastant quinine on food intake and appetite sensations: a randomised crossover trial. British Journal of Nutrition 125:1, pages 92-100.
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Manoj Reddy Medapati, Anjali Y. Bhagirath, Nisha Singh & Prashen Chelikani. 2022. The Pharmacology of Taste. The Pharmacology of Taste 177 202 .
Joanna Jeruzal-Świątecka, Wojciech Fendler & Wioletta Pietruszewska. (2020) Clinical Role of Extraoral Bitter Taste Receptors. International Journal of Molecular Sciences 21:14, pages 5156.
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Vida Bitarafan, Penelope C. E. Fitzgerald, Tanya J. Little, Wolfgang Meyerhof, Karen L. Jones, Tongzhi Wu, Michael Horowitz & Christine Feinle-Bisset. (2020) Intragastric administration of the bitter tastant quinine lowers the glycemic response to a nutrient drink without slowing gastric emptying in healthy men. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 318:2, pages R263-R273.
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Edward Walker, Kim Lo, Sze Tham, Malcolm Pahl, Dominic Lomiwes, Janine Cooney, Mark Wohlers & Pramod Gopal. (2019) New Zealand Bitter Hops Extract Reduces Hunger During a 24 h Water Only Fast. Nutrients 11:11, pages 2754.
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Vida Bitarafan, Penelope C E Fitzgerald, Tanya J Little, Wolfgang Meyerhof, Tongzhi Wu, Michael Horowitz & Christine Feinle-Bisset. (2019) Effects of Intraduodenal Infusion of the Bitter Tastant, Quinine, on Antropyloroduodenal Motility, Plasma Cholecystokinin, and Energy Intake in Healthy Men. Journal of Neurogastroenterology and Motility 25:3, pages 413-422.
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Christopher Kure Liu, Paule Valery Joseph, Dana E. Feldman, Danielle S. Kroll, Jamie A. Burns, Peter Manza, Nora D. Volkow & Gene-Jack Wang. (2019) Brain Imaging of Taste Perception in Obesity: a Review. Current Nutrition Reports 8:2, pages 108-119.
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Qiaoling Wang, Kathrin I. Liszt, Eveline Deloose, Emilio Canovai, Theo Thijs, Ricard Farré, Laurens J. Ceulemans, Matthias Lannoo, Jan Tack & Inge Depoortere. (2019) Obesity alters adrenergic and chemosensory signaling pathways that regulate ghrelin secretion in the human gut. The FASEB Journal 33:4, pages 4907-4920.
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Lauren P Manning & Jessica R Biesiekierski. (2018) Use of dietary interventions for functional gastrointestinal disorders. Current Opinion in Pharmacology 43, pages 132-138.
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Cong Xie, Xuyi Wang, Richard L. Young, Michael Horowitz, Christopher K. Rayner & Tongzhi Wu. (2018) Role of Intestinal Bitter Sensing in Enteroendocrine Hormone Secretion and Metabolic Control. Frontiers in Endocrinology 9.
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Nathalie Weltens, Julie Iven, Lukas Van Oudenhove & Michiko Kano. (2018) The gut–brain axis in health neuroscience: implications for functional gastrointestinal disorders and appetite regulation. Annals of the New York Academy of Sciences 1428:1, pages 129-150.
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