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Original Articles

Toxicokinetics of naringin and its metabolite naringenin after 180-day repeated oral administration in beagle dogs assayed by a rapid resolution liquid chromatography/tandem mass spectrometric method

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Pages 68-75 | Received 09 May 2011, Accepted 12 Oct 2011, Published online: 20 Jan 2012

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Irfan Ahmad Mir & Ashu Bhan Tiku. (2015) Chemopreventive and Therapeutic Potential of “Naringenin,” a Flavanone Present in Citrus Fruits. Nutrition and Cancer 67:1, pages 27-42.
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Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Fašmon Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Andrew Chesson, Johannes Westendorf, Paola Manini, Fabiola Pizzo & Birgit Dusemund. (2021) Safety and efficacy of a feed additive consisting of a flavonoid‐rich dried extract of Citrus × aurantium L. fruit (bitter orange extract) for use in all animal species (FEFANA asbl). EFSA Journal 19:7.
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Jinbin Yuan, Feiting Wei, Xizhen Luo, Min Zhang, Rifa Qiao, Minyong Zhong, Haifang Chen & Wuliang Yang. (2020) Multi-Component Comparative Pharmacokinetics in Rats After Oral Administration of Fructus aurantii Extract, Naringin, Neohesperidin, and Naringin-Neohesperidin. Frontiers in Pharmacology 11.
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Xuan Zeng, Weiwei Su, Buming Liu, Ling Chai, Rui Shi & Hongliang Yao. (2020) A Review on the Pharmacokinetic Properties of Naringin and Its Therapeutic Efficacies in Respiratory Diseases. Mini-Reviews in Medicinal Chemistry 20:4, pages 286-293.
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Peibo Li, Hao Wu, Yonggang Wang, Wei Peng & Weiwei Su. (2020) Toxicological evaluation of naringin: Acute, subchronic, and chronic toxicity in Beagle dogs. Regulatory Toxicology and Pharmacology 111, pages 104580.
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Sila Appak-Baskoy, Mustafa Cengiz, Ozgun Teksoy & Adnan Ayhanci. 2019. Strawberry - Pre- and Post-Harvest Management Techniques for Higher Fruit Quality. Strawberry - Pre- and Post-Harvest Management Techniques for Higher Fruit Quality.
Xia Zhang, Caijuan Liang, Jintuo Yin, Yupeng Sun & Lantong Zhang. (2018) Identification of metabolites of liquiritin in rats by UHPLC-Q-TOF-MS/MS: metabolic profiling and pathway comparison in vitro and in vivo . RSC Advances 8:21, pages 11813-11827.
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Stephanie Martinez, Ryan Lillico, Ted Lakowski, Steven Martinez & Neal Davies. (2017) Pharmacokinetic Analysis of an Oral Multicomponent Joint Dietary Supplement (Phycox®) in Dogs. Pharmaceutics 9:4, pages 30.
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Stephanie C. Casey, Amedeo Amedei, Katia Aquilano, Asfar S. Azmi, Fabian Benencia, Dipita Bhakta, Alan E. Bilsland, Chandra S. Boosani, Sophie Chen, Maria Rosa Ciriolo, Sarah Crawford, Hiromasa Fujii, Alexandros G. Georgakilas, Gunjan Guha, Dorota Halicka, William G. Helferich, Petr Heneberg, Kanya Honoki, W. Nicol Keith, Sid P. Kerkar, Sulma I. Mohammed, Elena Niccolai, Somaira Nowsheen, H.P. Vasantha Rupasinghe, Abbas Samadi, Neetu Singh, Wamidh H. Talib, Vasundara Venkateswaran, Richard L. Whelan, Xujuan Yang & Dean W. Felsher. (2015) Cancer prevention and therapy through the modulation of the tumor microenvironment. Seminars in Cancer Biology 35, pages S199-S223.
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Hao-yan Jiao, Wei-wei Su, Pei-bo Li, Yan Liao, Qian Zhou, Na Zhu & Li-li He. (2015) Therapeutic effects of naringin in a guinea pig model of ovalbumin-induced cough-variant asthma. Pulmonary Pharmacology & Therapeutics 33, pages 59-65.
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Sael Casas-Grajales. (2015) Antioxidants in liver health. World Journal of Gastrointestinal Pharmacology and Therapeutics 6:3, pages 59.
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Pulok K. Mukherjee, Ranjit K. Harwansh & Sauvik Bhattacharyya. 2015. Evidence-Based Validation of Herbal Medicine. Evidence-Based Validation of Herbal Medicine 217 245 .
Sheng Wang, Yonggang Wang, Yulong Luo, Ying Liu & Weiwei Su. (2013) In vitro and in vivo évaluation of naringin sustained-release pellets compared with immediate-release tablets. Journal of Drug Delivery Science and Technology 23:5, pages 459-464.
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