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Original Articles

Effects of capsaicin and dihydrocapsaicin on human and rat liver microsomal CYP450 enzyme activities in vitro and in vivo

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Pages 382-395 | Received 20 Jun 2011, Accepted 09 Jan 2012, Published online: 01 Mar 2012

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Read on this site (7)

Fengzhang Wang, Yong Xue, Lin Fu, Yongtao Wang, Minxia He, Liang Zhao & Xiaojun Liao. (2022) Extraction, purification, bioactivity and pharmacological effects of capsaicin: a review. Critical Reviews in Food Science and Nutrition 62:19, pages 5322-5348.
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Yun-Jing Zhang, Wen-Li Zhou, Fei Yu, Qian Wang, Can Peng & Jia-Yi Kan. (2021) Evaluation of the effect of Bovis Calculus Artifactus on eight rat liver cytochrome P450 isozymes using LC-MS/MS and cocktail approach. Xenobiotica 51:9, pages 1010-1018.
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Jinxiu Li, Haibin Wen & Zhiqiang Gao. (2020) In vitro inhibitory effects of phellodendrine on human liver cytochrome P450 enzymes. Xenobiotica 50:2, pages 154-159.
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Ning Zhang, Jing Liu, Zhixia Chen & Wenwen Dou. (2019) In vitro inhibitory effects of kaempferitrin on human liver cytochrome P450 enzymes. Pharmaceutical Biology 57:1, pages 571-576.
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Xiaoyi Hao, Jianlei Yuan, Yansen Xu, Zhao Wang, Jianzhang Hou & Tao Hu. (2018) In vitro inhibitory effects of pristimerin on human liver cytochrome P450 enzymes. Xenobiotica 48:12, pages 1185-1191.
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Articles from other publishers (12)

Adili Abulaiti, Zahid Naseer, Zulfiqar Ahmed, Wenju Liu, Xunsheng Pang, Muhammad Farooq Iqbal & Shujuan Wang. (2022) Dietary Supplementation of Capsaicin Enhances Productive and Reproductive Efficiency of Chinese Crossbred Buffaloes in Low Breeding Season. Animals 13:1, pages 118.
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Yunqiu Tang & Yunxia Li. (2022) Compound Shuganjieyu Capsule on CYP450 Enzyme Activity. BioMed Research International 2022, pages 1-8.
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Manoj Kumar Dash, Namrata Joshi, Vd. Sushil Dubey, Kamal Nayan Dwivedi & Dev Nath Singh Gautam. (2022) Screening of anti-cancerous potential of classical Raudra rasa and modified Raudra rasa modified with hiraka bhasma (nanodiamond) through FTIR & LC-MS analysis . Journal of Complementary and Integrative Medicine 19:3, pages 669-682.
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Wenjuan Ma, Wei Wang, Xuhua Huang, Guangzhe Yao, Qi Jia, Jiayuan Shen, Huizi Ouyang, Yanxu Chang & Jun He. (2020) HPLC-MS/MS Analysis of Aconiti Lateralis Radix Praeparata and Its Combination with Red Ginseng Effect on Rat CYP450 Activities Using the Cocktail Approach . Evidence-Based Complementary and Alternative Medicine 2020, pages 1-12.
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Mohammad Mohajeri, Behzad Behnam, Arrigo F. G. Cicero & Amirhossein Sahebkar. (2018) Protective effects of curcumin against aflatoxicosis: A comprehensive review. Journal of Cellular Physiology 233:4, pages 3552-3577.
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Brunno Felipe Ramos Caetano, Mariana Baptista Tablas, Natália Elias Ferreira Pereira, Nelci Antunes de Moura, Robson Francisco Carvalho, Maria Aparecida Marchesan Rodrigues & Luis Fernando Barbisan. (2018) Capsaicin reduces genotoxicity, colonic cell proliferation and preneoplastic lesions induced by 1,2-dimethylhydrazine in rats. Toxicology and Applied Pharmacology 338, pages 93-102.
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Suhaili Shamsi, Huong Tran, Renee Seok Jin Tan, Zee Jian Tan & Lee Yong Lim. (2017) Curcumin, Piperine, and Capsaicin: A Comparative Study of Spice-Mediated Inhibition of Human Cytochrome P450 Isozyme Activities. Drug Metabolism and Disposition 45:1, pages 49-55.
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Wuhong Li, Liang Zhao, Jian Le, Yinying Zhang, Yinli Liu, Guoqing Zhang, Yifeng Chai & Zhanying Hong. (2015) Evaluation of Tetrahydropalmatine Enantiomers on the Activity of Five Cytochrome P450 Isozymes in Rats Using a Liquid Chromatography / Mass Spectrometric Method and a Cocktail Approach. Chirality 27:8, pages 551-556.
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Shanna Bitencourt, Leslie Stradiot, Stefaan Verhulst, Lien Thoen, Inge Mannaerts & Leo A. van Grunsven. (2015) Inhibitory effect of dietary capsaicin on liver fibrosis in mice. Molecular Nutrition & Food Research 59:6, pages 1107-1116.
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Yunfang Zhou, Shuanghu Wang, Ting Ding, Mengchun Chen, Li Wang, Mingdong Wu, Guoxin Hu & Xianghong Lu. (2014) Evaluation of the effect of apatinib (YN968D1) on cytochrome P450 enzymes with cocktail probe drugs in rats by UPLC–MS/MS. Journal of Chromatography B 973, pages 68-75.
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Inés Díaz-Laviada & Nieves Rodríguez-Henche. 2014. Capsaicin as a Therapeutic Molecule. Capsaicin as a Therapeutic Molecule 181 208 .
Peijian Wang, Zhencheng Yan, Jian Zhong, Jing Chen, Yinxing Ni, Li Li, Liqun Ma, Zhigang Zhao, Daoyan Liu & Zhiming Zhu. (2012) Transient Receptor Potential Vanilloid 1 Activation Enhances Gut Glucagon-Like Peptide-1 Secretion and Improves Glucose Homeostasis. Diabetes 61:8, pages 2155-2165.
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