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Journal of Asian Natural Products Research Volume 14, 2012 - Issue 6
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Original Articles

Partial synthesis and biological evaluation of bisbenzylisoquinoline alkaloids derivatives: potential modulators of multidrug resistance in cancer

Ping He Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, 610041, China
,
Hua Sun Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, 100050, China
,
Xi-Xian Jian Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, 610041, China
,
Qiao-Hong Chen Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, 610041, China
,
Dong-Lin Chen Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, 610041, China
,
Geng-Tao Liu Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, 100050, China
&
Feng-Peng Wang Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, 610041, ChinaCorrespondence[email protected]
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Pages 564-576 | Received 04 Jan 2012, Accepted 26 Mar 2012, Published online: 15 May 2012

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Qian-Hao Yang, Cheng-Shi Jiang, Tao Jin, Jin-Fang Xu, Ting-Li Qu, Yue-Wei Guo & Zheng-Bao Zhao. (2018) Synthesis of novel tetrandrine derivatives and their inhibition against NSCLC A549 cells. Journal of Asian Natural Products Research 20:11, pages 1064-1074.
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Xiao Wei, Ting-Li Qu, Yi-Fang Yang, Jin-Fang Xu, Xu-Wen Li, Zheng-Bao Zhao & Yue-Wei Guo. (2016) Design and synthesis of new tetrandrine derivatives and their antitumor activities. Journal of Asian Natural Products Research 18:10, pages 966-975.
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Chun-Zhen Wu, Long Lai, Xiao Hu, Rong-Rong Lei & Yi-Fang Yang. (2013) Synthesis and antitumor activity of tetrandrine derivatives. Journal of Asian Natural Products Research 15:9, pages 993-1002.
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Articles from other publishers (11)

Jia-shu Chen, Xu Guo, Jin-yue Sun, Mu-xuan Wang, Xiu-zheng Gao, Zhen Wang, Jin-long Han, Hui Sun, Kai Zhang & Chao Liu. (2023) Fangchinoline derivatives inhibits PI3K signaling in vitro and in vivo in non-small cell lung cancer. Bioorganic Chemistry 138, pages 106623.
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Sandra Mónica González-Martínez, Drochss Pettry Valencia-Ochoa, Juan Carlos Gálvez-Ruiz, Mario Alberto Leyva-Peralta, Octavio Juárez-Sánchez, María A. Islas-Osuna, Viviana Isabel Calvillo-Páez, Herbert Höpfl, Ramón Íñiguez-Palomares, Fernando Rocha-Alonzo & Karen Ochoa Lara. (2022) DNA-Binding Properties of Bis- N -substituted Tetrandrine Derivatives . ACS Omega 7:19, pages 16380-16390.
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Xiu-zheng Gao, Xu-tao Lv, Rui-rui Zhang, Yang Luo, Mu-xuan Wang, Jia-shu Chen, Yu-kai Zhang, Bin Sun, Jin-yue Sun, Yu-fa Liu & Chao Liu. (2021) Design, synthesis and in vitro anticancer research of novel tetrandrine and fangchinoline derivatives. Bioorganic Chemistry 109, pages 104694.
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Qi Wang, Baohe Tang & Minhui Cao. (2020) Synthesis, characterization, and fungicidal activity of novel Fangchinoline derivatives. Bioorganic & Medicinal Chemistry 28:23, pages 115778.
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Yan-chun Zhang, Xiu-zheng Gao, Chao Liu, Mu-xuan Wang, Rui-rui Zhang, Jin-yue Sun & Yu-fa Liu. (2020) Design, synthesis and in vitro evaluation of fangchinoline derivatives as potential anticancer agents. Bioorganic Chemistry 94, pages 103431.
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Nana Niu, Tao Jin, Xia LiJinfang Xu, Tingli Qu, Graham J. Bodwell & Zhengbao Zhao. (2019) Design and Synthesis of Tetrandrine Derivatives as Potential Anti-tumor Agents Against A549 Cell Lines. ChemistrySelect 4:1, pages 196-201.
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Fidelia Ijeoma Uche, James McCullagh, Timothy W.D. Claridge, Alan Richardson & Wen-Wu Li. (2018) Synthesis of (aminoalkyl)cycleanine analogues: cytotoxicity, cellular uptake, and apoptosis induction in ovarian cancer cells. Bioorganic & Medicinal Chemistry Letters 28:9, pages 1652-1656.
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Viviana Calvillo-Páez, Rogerio R. Sotelo-Mundo, Mario Leyva-Peralta, Juan Carlos Gálvez-Ruiz, David Corona-Martínez, Ramón Moreno-Corral, Raymundo Escobar-Picos, Herbert Höpfl, Octavio Juárez-Sánchez & Karen Ochoa Lara. (2018) Synthesis, spectroscopic, physicochemical and structural characterization of tetrandrine-based macrocycles functionalized with acridine and anthracene groups: DNA binding and anti-proliferative activity. Chemico-Biological Interactions 286, pages 34-44.
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Fuqiang Zhu, Haji A. Aisa, Jian Zhang, Tianwen Hu, Changliang Sun, Yang He, Yuanchao Xie & Jingshan Shen. (2018) Development of a Robust Process for the Preparation of High-Quality 4-Methylenepiperidine Hydrochloride. Organic Process Research & Development 22:1, pages 91-96.
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Ting Liu, Xin Liu & Wenhua Li. (2016) Tetrandrine, a Chinese plant-derived alkaloid, is a potential candidate for cancer chemotherapy. Oncotarget 7:26, pages 40800-40815.
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YUPING WANG, JIE CHEN, LIN WANG, YUJI HUANG, YE LENG & GUIYING WANG. (2013) Fangchinoline induces G0/G1 arrest by modulating the expression of CDKN1A and CCND2 in K562 human chronic myelogenous leukemia cells. Experimental and Therapeutic Medicine 5:4, pages 1105-1112.
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