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Original Articles

Cytotoxic activity of Pulsatilla chinensis saponins and their structure–activity relationship

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Pages 680-686 | Received 19 Oct 2012, Accepted 26 Mar 2013, Published online: 10 May 2013

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Zeng-Guang Zhang, Yuan-Yuan Li, Bin Lin, Pei-Pei Guan, Yu Mu, Wen-Jun Qiao, Jing-Sheng Zhang, Xue-Shi Huang & Li Han. (2022) New phenolic glycosides from Anemone chinensis Bunge and their antioxidant activity. Natural Product Research 36:19, pages 5009-5015.
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Articles from other publishers (27)

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Tinglan Zhang, Jun Zhang, Fangfang Chen, An Liu, Jinzhu Jiang, Zhiyong Yan & Xianju Liu. (2023) Qualitative and quantitative analysis of triterpenoids in different tissues of Pulsatilla chinensis. Journal of Pharmaceutical and Biomedical Analysis 234, pages 115528.
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Zengguang Zhang, Wenfei Xu, Lixiao Xu, Guiding Li, Nuerbiye Aobulikasimu, Jingyi Gao, Yixuan Hu, Peipei Guan, Yu Mu, Xueshi Huang & Li Han. (2023) Discovery, Preliminary Structure–Activity Relationship, and Evaluation of Oleanane-Type Saponins from Pulsatilla chinensis for the Treatment of Ulcerative Colitis . Journal of Medicinal Chemistry 66:5, pages 3635-3647.
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Xianju Liu, Yudi Xu, Jipeng Di, An Liu & Jinzhu Jiang. (2023) The triterpenoid saponin content difference is associated with the two type oxidosqualene cyclase gene copy numbers of Pulsatilla chinensis and Pulsatilla cernua. Frontiers in Plant Science 14.
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Irma Podolak, Karolina Grabowska, Danuta Sobolewska, Dagmara Wróbel-Biedrawa, Justyna Makowska-Wąs & Agnieszka Galanty. (2022) Saponins as cytotoxic agents: an update (2010–2021). Part II—Triterpene saponins. Phytochemistry Reviews 22:1, pages 113-167.
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Grażyna Łaska, Elwira Sieniawska, Magdalena Maciejewska-Turska, Łukasz Świątek, David S. Pasco & Premalatha Balachandran. (2023) Pulsatilla vulgaris Inhibits Cancer Proliferation in Signaling Pathways of 12 Reporter Genes. International Journal of Molecular Sciences 24:2, pages 1139.
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Yanjing Dong, Qian Qin, Guoyue Zhong, Zejing Mu, Yating Cai, Xiaoyun Wang, Huan Xie & Shouwen Zhang. (2023) Integrated transcriptomic and metabolomic analyses revealed the molecular mechanism of terpenoid formation for salicylic acid resistance in Pulsatilla chinensis callus. Frontiers in Plant Science 13.
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Jinmiao Zhong, Lihua Tan, Meiwan Chen & Chengwei He. (2022) Pharmacological activities and molecular mechanisms of Pulsatilla saponins. Chinese Medicine 17:1.
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Hang Li, Lilan Wang, Xiaojing Zhang, Wenxin Xia, Xirong Zhou, Hong Sui & Xueyan Fu. (2022) Pulsatilla chinensis (Bge.) Regel: A Systematic Review on Anticancer of Its Pharmacological Properties, Clinical Researches and Pharmacokinetic Studies. Frontiers in Oncology 12.
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Zefeng Zhao, Meng Nian, Haifa Qiao, Bin Li & Xiaohui Zheng. (2021) Pulsatilla chinensis: A review of traditional uses, phytochemistry and pharmacology research progress. Arabian Journal of Chemistry 14:11, pages 103403.
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Olusola Olalekan Elekofehinti, Opeyemi Iwaloye, Femi Olawale & Esther Opeyemi Ariyo. (2021) Saponins in Cancer Treatment: Current Progress and Future Prospects. Pathophysiology 28:2, pages 250-272.
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Yan-hong Li, Min Zou, Qian Han, Li-rong Deng & Richard M. Weinshilboum. (2020) Therapeutic potential of triterpenoid saponin anemoside B4 from Pulsatilla chinensis. Pharmacological Research 160, pages 105079.
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Qin Gong, Lu-Ling He, Mu-Lan Wang, Hui Ouyang, Hong-Wei Gao, Yu-Lin Feng, Shi-Lin Yang, Li-Jun Du, Jun Li & Ying-Ying Luo. (2019) Anemoside B4 Protects Rat Kidney from Adenine-Induced Injury by Attenuating Inflammation and Fibrosis and Enhancing Podocin and Nephrin Expression. Evidence-Based Complementary and Alternative Medicine 2019, pages 1-11.
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Luan He, Yong Zhang, Naixin Kang, Yaner Wang, Ziyu Zhang, Zhengxia Zha, Shilin Yang, Qiongming Xu & Yanli Liu. (2019) Anemoside B4 attenuates nephrotoxicity of cisplatin without reducing anti-tumor activity of cisplatin. Phytomedicine 56, pages 136-146.
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Da-Cheng Hao. 2019. Ranunculales Medicinal Plants. Ranunculales Medicinal Plants 223 259 .
Miao-miao Jin, Wen-dan Zhang, Hong-hong Jiang, Ying-feng Du, Wei Guo, Liang Cao & Hui-jun Xu. (2018) UPLC-Q-TOF-MS/MS-guided dereplication of Pulsatilla chinensis to identify triterpenoid saponins . Phytochemical Analysis 29:5, pages 516-527.
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Elena I. Fedoros, Alexey A. Orlov, Alexander Zherebker, Ekaterina A. Gubareva, Mikhail A. Maydin, Andrey I. Konstantinov, Konstantin A. Krasnov, Ruben N. Karapetian, Ekaterina I. Izotova, Sergey E. Pigarev, Andrey V. Panchenko, Margarita L. Tyndyk, Dmitry I. Osolodkin, Evgeny N. Nikolaev, Irina V. Perminova & Vladimir N. Anisimov. (2018) Novel water-soluble lignin derivative BP-Cx-1: identification of components and screening of potential targets in silico and in vitro . Oncotarget 9:26, pages 18578-18593.
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Yan-Er Wang, Kun Xu, Wen-Hua Yue, Qiong-Ming Xu, Ben-Gang You, Mi-Ya Zhang, Zhan-Cheng Zhu, Shi-Lin Yang, Yan-Li Liu & Kun-Ping Li. (2018) Hederacolchiside A1 suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway. Chinese Herbal Medicines 10:2, pages 215-222.
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Miao-Miao Jin, Wen-Dan Zhang, Geng-Shen Song, Yan-Mei Xu, Ying-Feng Du, Wei Guo, Liang Cao & Hui-Jun Xu. (2018) Discrimination and Chemical Phylogenetic Study of Four Pulsatilla Herbs Using UPLC–ESI–MS/MS Combined with Hierarchical Cluster Analysis. Journal of Chromatographic Science 56:3, pages 216-224.
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Marco A. Loza-Mejía & Juan Rodrigo Salazar. (2015) Sterols and triterpenoids as potential anti-inflammatories: Molecular docking studies for binding to some enzymes involved in inflammatory pathways. Journal of Molecular Graphics and Modelling 62, pages 18-25.
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Jun-Rong Du, Fang-Yi Long & Chu Chen. 2014. Natural Products and Cancer Signaling: Isoprenoids, Polyphenols and Flavonoids. Natural Products and Cancer Signaling: Isoprenoids, Polyphenols and Flavonoids 95 130 .

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