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Original Articles

Synthesis of phthalide derivatives and evaluation on their antiplatelet aggregation and antioxidant activities

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Pages 1176-1187 | Received 14 Jun 2019, Accepted 14 Oct 2019, Published online: 22 Nov 2019

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Zeynep Tanrıkulu Yılmaz, Hakkı Yasin Odabaşoğlu, Pelin Şenel, Elif Çepni Yüzbaşıoğlu, Taner Erdoğan, Ayşe Daut Özdemir, Ayşegül Gölcü, Mustafa Odabaşoğlu & Orhan Büyükgüngör. (2023) Identification of a 3-(5-methyl-2-thiazolylamino)phthalide as a new minor groove agent. Journal of Biomolecular Structure and Dynamics 41:9, pages 4048-4064.
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Qinyang Yu, Bilan Luo, Zhongfu Luo, Xu Zhong, Yi Li, Yi Zhang, Gaofeng Zhu, Bing Guo, Lei Tang, Yong Li & Lingling Fan. (2022) Synthesis of Novel 3‐Butylphthalide Derivatives Containing Isopentenylphenol Moiety as Potential Antiplatelet Agents for the Treatment of Ischemic Stroke. Chemistry & Biodiversity 20:1.
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Liu-Yan Wang, Wen-Yan Li, Hao-Feng Zhou, Xue-Yu Zhao, Xiao-Nian Li, Xing-De Wu & Qin-Shi Zhao. (2022) Spiroligustolides A and B: Two pairs of enantiomeric spiro-orthoester-containing phthalide dimers as Cav3.1 calcium channel inhibitors from Ligusticum Chuanxiong Hort. Bioorganic Chemistry 123, pages 105749.
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Dan Li, Yu Long, Shuang Yu, Ai Shi, Jinyan Wan, Jing Wen, Xiaoqiu Li, Songyu Liu, Yulu Zhang, Nan Li, Chuan Zheng, Ming Yang & Lin Shen. (2022) Research Advances in Cardio-Cerebrovascular Diseases of Ligusticum chuanxiong Hort.. Frontiers in Pharmacology 12.
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José Marco-Contelles & Yihua Zhang. (2020) From Seeds of Apium graveolens Linn. to a Cerebral Ischemia Medicine: The Long Journey of 3- n -Butylphthalide . Journal of Medicinal Chemistry 63:21, pages 12485-12510.
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Rafael Mascoloti Spréa, Ângela Fernandes, Tiane C. Finimundy, Carla Pereira, Maria José Alves, Ricardo C. Calhelha, Cristiane Canan, Lillian Barros, Joana S. Amaral & Isabel C. F. R. Ferreira. (2020) Lovage (Levisticum officinale W.D.J. Koch) Roots: A Source of Bioactive Compounds towards a Circular Economy. Resources 9:7, pages 81.
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