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Journal of Asian Natural Products Research Volume 24, 2022 - Issue 3
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Quercetin attenuates ischemia reperfusion injury by protecting the blood-brain barrier through Sirt1 in MCAO rats

Ran YangBeijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100050, ChinaORCID Iconhttps://orcid.org/0000-0002-0394-3499View further author information
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Yan-Jia ShenBeijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100050, ChinaORCID Iconhttps://orcid.org/0000-0002-4887-0975View further author information
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Miao ChenBeijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100050, ChinaORCID Iconhttps://orcid.org/0000-0002-9195-8542View further author information
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Jia-Ying ZhaoBeijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100050, ChinaORCID Iconhttps://orcid.org/0000-0002-9907-5023View further author information
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Shu-Han ChenBeijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100050, ChinaORCID Iconhttps://orcid.org/0000-0002-1873-7540View further author information
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Wen ZhangBeijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100050, ChinaORCID Iconhttps://orcid.org/0000-0002-1817-8873View further author information
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Jun-Ke SongBeijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100050, ChinaORCID Iconhttps://orcid.org/0000-0002-4379-0909View further author information
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Li LiBeijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100050, ChinaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0001-6246-6605View further author information
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Guan-Hua DuBeijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100050, ChinaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0002-6896-0847View further author information
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Pages 278-289 | Received 24 Mar 2021, Accepted 25 Jun 2021, Published online: 22 Jul 2021

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Wenhai Guo, Danping Huang & Shaodong Li. (2023) Lycopene alleviates oxidative stress-induced cell injury in human vascular endothelial cells by encouraging the SIRT1/Nrf2/HO-1 pathway. Clinical and Experimental Hypertension 45:1.
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Ke Zhu, Zhong Zheng, Ya-yun Zhang, Zhuo-yao Li, Ai-fang Zhou, Cai-wei Hu, Bing Shu, Long-yun Zhou, Qi Shi, Yong-jun Wang, Min Yao & Xue-jun Cui. (2023) A comprehensive and systematic review of the potential neuroprotective effect of quercetin in rat models of spinal cord injury. Nutritional Neuroscience 0:0, pages 1-13.
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Articles from other publishers (15)

Yafang Zhang, Ke Fu, Cheng Wang, Cheng Ma, Lihong Gong, Honglin Zhou, Xinyan Xue, Cheng Peng & Yunxia Li. (2023) Protective effects of dietary quercetin on cerebral ischemic injury: pharmacology, pharmacokinetics and bioavailability-enhancing nanoformulations. Food & Function 14:10, pages 4470-4489.
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Dian Jiao, Jianmiao Xu, Chengjian Lou, Yuhuan Luo, Chengtao Ni, Guanghong Shen, Marong Fang & Xiangyang Gong. (2022) Quercetin alleviates subarachnoid hemorrhage‐induced early brain injury via inhibiting ferroptosis in the rat model. The Anatomical Record 306:3, pages 638-650.
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Ignacio Moratilla-Rivera, Marta Sánchez, Jose Antonio Valdés-González & María Pilar Gómez-Serranillos. (2023) Natural Products as Modulators of Nrf2 Signaling Pathway in Neuroprotection. International Journal of Molecular Sciences 24:4, pages 3748.
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Paolo Bellavite. (2023) Neuroprotective Potentials of Flavonoids: Experimental Studies and Mechanisms of Action. Antioxidants 12:2, pages 280.
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Faheem Shehjar, Briana Maktabi, Zainab A. Rahman, Ghaith A. Bahader, Antonisamy William James, Ahmed Naqvi, Reetika Mahajan & Zahoor A. Shah. (2023) Stroke: Molecular mechanisms and therapies: Update on recent developments. Neurochemistry International 162, pages 105458.
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Jin-Fu Peng, Oluwabukunmi Modupe Salami, Olive Habimana, Yu-Xin Xie, Hui Yao & Guang-Hui Yi. (2022) Targeted Mitochondrial Drugs for Treatment of Ischemia-Reperfusion Injury. Current Drug Targets 23:16, pages 1526-1536.
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Kade Riche & Natalie R. Lenard. (2022) Quercetin’s Effects on Glutamate Cytotoxicity. Molecules 27:21, pages 7620.
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Chaoyou Fang, Houshi Xu, Ling Yuan, Zhengyang Zhu, Xiaoyu Wang, Yibo Liu, Anke Zhang, Anwen Shao & Meiqing Lou. (2022) Natural Compounds for SIRT1-Mediated Oxidative Stress and Neuroinflammation in Stroke: A Potential Therapeutic Target in the Future. Oxidative Medicine and Cellular Longevity 2022, pages 1-16.
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Attilio Marino, Matteo Battaglini, Nadia Moles & Gianni Ciofani. (2022) Natural Antioxidant Compounds as Potential Pharmaceutical Tools against Neurodegenerative Diseases. ACS Omega 7:30, pages 25974-25990.
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Zhifu Cui, Xingtao Zhao, Felix Kwame Amevor, Xiaxia Du, Yan Wang, Diyan Li, Gang Shu, Yaofu Tian & Xiaoling Zhao. (2022) Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism. Frontiers in Immunology 13.
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Chuan Qin, Sheng Yang, Yun-Hui Chu, Hang Zhang, Xiao-Wei Pang, Lian Chen, Luo-Qi Zhou, Man Chen, Dai-Shi Tian & Wei Wang. (2022) Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions. Signal Transduction and Targeted Therapy 7:1.
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Shuhan Liu, Feng Lin, Jian Wang, Xiaoqiang Pan, Liguang Sun & Wei Wu. (2022) Polyphenols for the Treatment of Ischemic Stroke: New Applications and Insights. Molecules 27:13, pages 4181.
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Leilei Zhang, Jingying Ma, Fan Yang, Sishi Li, Wangran Ma, Xiang Chang & Lin Yang. (2022) Neuroprotective Effects of Quercetin on Ischemic Stroke: A Literature Review. Frontiers in Pharmacology 13.
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Anqi Xu, Zhuo-Hua Wen, Shi-Xing Su, Yu-Peng Chen, Wen-Chao Liu, Shen-Quan Guo, Xi-Feng Li, Xin Zhang, Ran Li, Ning-Bo Xu, Ke-Xin Wang, Wen-Xing Li, Dao-Gang Guan & Chuan-Zhi Duan. (2022) Elucidating the Synergistic Effect of Multiple Chinese Herbal Prescriptions in the Treatment of Post-stroke Neurological Damage. Frontiers in Pharmacology 13.
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Chao Guo, Wen-Jun Wang, Yu-Cheng Liao, Chao Zhao, Ying Yin, Min-Na Yao, Yi Ding & Jing-Wen Wang. (2022) Effect and Mechanisms of Quercetin for Experimental Focal Cerebral Ischemia: A Systematic Review and Meta-Analysis. Oxidative Medicine and Cellular Longevity 2022, pages 1-13.
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