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Journal of Asian Natural Products Research Volume 3, 2001 - Issue 3
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Original Articles

The Structure of Physalin T from Physalis alkekengi var. francheti

Masao Kawai
,
Tatsuo Yamamoto Department of Applied Chemistry, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, 466-8555, Japan
,
Bunsho Makino Department of Applied Chemistry, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, 466-8555, Japan; Kampo and Pharmacognosy Laboratory, Tsumura and Co., 3586 Yoshiwara, Ami-machi, Inashiki-gun, Ibaraki, 300-1192, Japan
,
Hatsuo Yamamura Department of Applied Chemistry, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, 466-8555, Japan
,
Shuki Araki Department of Applied Chemistry, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, 466-8555, Japan
,
Yasuo Butsugan Department of Applied Chemistry, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, 466-8555, Japan
&
Kazuki Saito Yokoyama CytoLogic Project, ERATO, Japan Science and Technology Corporation, c/o Tsukuba Research Consortium, 5-9-1 Tokodai, Tsukuba, 300-2635, Japan
 show all
Pages 199-205 | Received 15 May 2000, Accepted 16 Sep 2000, Published online: 04 Oct 2006

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Jia-Min Sun, Ji-Xiang He, Min Huang, Hui-Xin Hu, Lin-Tao Xu, Kai-Li Fang, Xiao-Ning Wang & Tao Shen. (2022) Two new physalins from Physalis alkekengi L. var. franchetii (Mast.) Makino. Natural Product Research 36:20, pages 5206-5212.
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S. Helvacı, G. Kökdil, M. Kawai, N. Duran, G. Duran & A. Güvenç. (2010) Antimicrobial activity of the extracts and physalin D from Physalis alkekengi and evaluation of antioxidant potential of physalin D. Pharmaceutical Biology 48:2, pages 142-150.
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Articles from other publishers (21)

Yiru Liu, Xu Wang, Chenxue Li, Dahai Yu, Bing Tian, Wenlan Li & Zhiwei Sun. (2023) Research progress on the chemical components and pharmacological effects of Physalis alkekengi L. var. franchetii (Mast.) Makino. Heliyon 9:12, pages e20030.
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Hesham S. M. Soliman, Eslam M. Korany, Elsayed K. El-Sayed, Ahmed M. Aboelyazed & Haitham A. Ibrahim. (2023) Nephroprotective effect of Physalis peruviana L. calyx extract and its butanolic fraction against cadmium chloride toxicity in rats and molecular docking of isolated compounds. BMC Complementary Medicine and Therapies 23:1.
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Bing-Wei He, Fei-Fei Wang & Li-Ping Qu. (2022) Anti-Inflammatory and Antioxidant Properties of Physalis alkekengi L. Extracts In Vitro and In Vivo: Potential Application for Skin Care. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-16.
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Jiangping Wu, Jianping Zhao, Tao Zhang, Yucheng Gu, Ikhlas A. Khan, Zhongmei Zou & Qiongming Xu. (2021) Naturally occurring physalins from the genus Physalis: A review. Phytochemistry 191, pages 112925.
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Guo-Bo Xu, Ya-Ming Xu, E. M. Kithsiri Wijeratne, Fatemeh Ranjbar, Manping X. Liu & A. A. Leslie Gunatilaka. (2021) Cytotoxic Physalins from Aeroponically Grown Physalis acutifolia . Journal of Natural Products 84:2, pages 187-194.
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Makoto Yoritate, Yuki Morita, Manuel Gemander, Masaki Morita, Tomohiro Yamashita, Mikiko Sodeoka & Go Hirai. (2020) Synthesis of DFGH-Ring Derivatives of Physalins via One-Pot Construction of GH-Ring and Evaluation of Their NF-κB-Inhibitory Activity. Organic Letters 22:22, pages 8877-8881.
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Ai-Ling Li, Bang-Jiao Chen, Guo-Hui Li, Ming-Xing Zhou, Yan-Ru Li, Dong-Mei Ren, Hong-Xiang Lou, Xiao-Ning Wang & Tao Shen. (2018) Physalis alkekengi L. var. franchetii (Mast.) Makino: An ethnomedical, phytochemical and pharmacological review. Journal of Ethnopharmacology 210, pages 260-274.
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Eva Kranjc, Alen Albreht, Irena Vovk & Vesna Glavnik. (2017) High performance thin-layer chromatography–mass spectrometry enables reliable analysis of physalins in different plant parts of Physalis alkekengi L.. Journal of Chromatography A 1526, pages 137-150.
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Masaki Morita, Shuntaro Kojima, Megumi Ohkubo, Hiroyuki Koshino, Daisuke Hashizume, Go Hirai, Keiji Maruoka & Mikiko Sodeoka. (2016) Synthesis of the Right‐Side Structure of Type B Physalins. Israel Journal of Chemistry 57:3-4, pages 309-318.
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Wen-Na Zhang & Wang-Yu Tong. (2016) Chemical Constituents and Biological Activities of Plants from the Genus Physalis . Chemistry & Biodiversity 13:1, pages 48-65.
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Xinli Li, Cuili Zhang, Weiling Li, Dachang Wu, Jianjun Liu, Li Tang & Yi Xin. (2013) In vivo effects on the intestinal microflora of Physalis alkekengi var. francheti extracts. Fitoterapia 87, pages 43-48.
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M. Iqbal Choudhary, Sammer Yousuf & Atta-ur-Rahman. 2013. Natural Products. Natural Products 3465 3495 .
Yunliang Zheng, Lianjun Luan, Yong Chen, Yiping Ren & Yongjiang Wu. (2012) Characterization of physalins and fingerprint analysis for the quality evaluation of Physalis alkekengi L. var. franchetii by ultra-performance liquid chromatography combined with diode array detection and electrospray ionization tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 71, pages 54-62.
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Xinli Li, Cuili Zhang, Dachang Wu, Li Tang, Xuejiao Cao & Yi Xin. (2012) In vitro effects on intestinal bacterium of physalins from Physalis alkekengi var. Francheti. Fitoterapia 83:8, pages 1460-1465.
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Li-Xia Chen, Hao He & Feng Qiu. (2011) Natural withanolides: an overview. Natural Product Reports 28:4, pages 705.
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Rosana I. Misico, Viviana E. Nicotra, Juan C. Oberti, Gloria Barboza, Roberto R. Gil & Gerardo Burton. 2011. Progress in the Chemistry of Organic Natural Products Vol. 94. Progress in the Chemistry of Organic Natural Products Vol. 94 127 229 .
Megumi Ohkubo, Go Hirai & Mikiko Sodeoka. (2009) Synthesis of the DFGH ring system of Type B Physalins: Highly Oxygenated, Cage-Shaped Molecules. Angewandte Chemie International Edition 48:21, pages 3862-3866.
Crossref
Megumi Ohkubo, Go Hirai & Mikiko Sodeoka. (2009) Synthesis of the DFGH ring system of Type B Physalins: Highly Oxygenated, Cage-Shaped Molecules. Angewandte Chemie 121:21, pages 3920-3924.
Crossref
Li Qiu, Feng Zhao, Hongwei Liu, Lixia Chen, Zhihu Jiang, Hongxia Liu, Naili Wang, Xinsheng Yao & Feng Qiu. (2008) Two New Megastigmane Glycosides, Physanosides A and B, from Physalis alkekengi L. var. franchetii , and Their Effect on NO Release in Macrophages . Chemistry & Biodiversity 5:5, pages 758-763.
Crossref
Amooru G. DamuPing-Chung KuoChung-Ren SuTsung-Hsiao KuoTzu-Hsuan ChenKenneth F. BastowKuo-Hsiung LeeTian-Shung Wu. (2007) Isolation, Structures, and Structure−Cytotoxic Activity Relationships of Withanolides and Physalins from Physalis angulata . Journal of Natural Products 70:7, pages 1146-1152.
Crossref
Ping-Chung KuoTsung-Hsiao KuoAmooru G. DamuChung-Ren SuE-Jian LeeTian-Shung WuRexen ShuChou-Ming ChenKenneth F. BastowTzu-Hsuan ChenKuo-Hsiung Lee. (2006) Physanolide A, a Novel Skeleton Steroid, and Other Cytotoxic Principles from Physalis a ngulata . Organic Letters 8:14, pages 2953-2956.
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