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Original Articles

Studies on the alkaloid constituents of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang and their acute toxicity in mice

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Pages 697-703 | Received 12 Jan 2004, Accepted 19 May 2004, Published online: 06 Dec 2006

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Read on this site (7)

Bo Wen & Peter Gorycki. (2019) Bioactivation of herbal constituents: mechanisms and toxicological relevance. Drug Metabolism Reviews 51:4, pages 453-497.
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Xiao-Long Zhang, Jie Sun, Hong-Hua Wu, Ya-Kun Jing, Xin Chai & Yue-Fei Wang. (2013) A new indoloquinazoline alkaloidal glucoside from the nearly ripe fruits of Evodia rutaecarpa. Natural Product Research 27:20, pages 1917-1921.
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Xin-Bao Yang, Ping Qian, Xiu-Wei Yang, Jian-Xun Liu, Ning-Bo Gong & Yang Lv. (2013) Limonoid constituents of Euodia rutaecarpa var. bodinieri and their inhibition on NO production in lipopolysaccharide-activated RAW264.7 macrophages. Journal of Asian Natural Products Research 15:10, pages 1130-1138.
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Chuan-Qin Hu, Ke-Ke Li & Xiu-Wei Yang. (2012) New glycosidic alkaloid from the nearly ripe fruits of Euodia rutaecarpa . Journal of Asian Natural Products Research 14:7, pages 634-639.
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Xin Huang, You-Bo Zhang & Xiu-Wei Yang. (2011) Indoloquinazoline alkaloids from Euodia rutaecarpa and their cytotoxic activities. Journal of Asian Natural Products Research 13:11, pages 977-983.
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Yue-Fei Wang, Ya-Nan Liu, Li-Min Hu, Gui-Xiang Pan & Xiu-Mei Gao. (2011) A QUALITATIVE AND QUANTITATIVE ASSESSMENT OF EIGHT CONSTITUENTS IN FRUCTUS EVODIAE BY HPLC-DAD-ESI-MS/MS. Journal of Liquid Chromatography & Related Technologies 34:6, pages 408-420.
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Shijie Zhong, Haoye Ye, Aihua Peng, Jie Shi, Shichao He, Shucai Li, Xia Ye, Minghai Tang & Lijuan Chen. (2011) Separation and Purification of Quinolone Alkaloids from the Chinese Herbal Medicine Evodia rutaecarpa (Juss.) Benth by High Performance Counter-Current Chromatography. Separation Science and Technology 46:5, pages 869-875.
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Articles from other publishers (27)

Si-Jia Xiao, Xi-Ke Xu, Wei Chen, Jia-Yun Xin, Wen-Lin Yuan, Xian-Peng Zu & Yun-Heng Shen. (2023) Traditional Chinese medicine Euodiae Fructus: botany, traditional use, phytochemistry, pharmacology, toxicity and quality control. Natural Products and Bioprospecting 13:1.
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Yubing Li, Xinyu Deng, Huiling Xiong, Qichao Hu, Yuan Chen, Wenwen Zhang, Xiao Ma & Yanling Zhao. (2023) Deciphering the toxicity-effect relationship and action patterns of traditional Chinese medicines from a smart data perspective: a comprehensive review. Frontiers in Pharmacology 14.
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Munmun Panda, Surya Kant Tripathi, Gokhan Zengin & Bijesh K. Biswal. (2022) Evodiamine as an anticancer agent: a comprehensive review on its therapeutic application, pharmacokinetic, toxicity, and metabolism in various cancers. Cell Biology and Toxicology 39:1, pages 1-31.
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Yangyang Wang, Hongying Ma, Acharan Narula, Lian Liu & Kwang Seok Ahn. (2022) Molecular targets and anticancer potential of evodiamine. Phytochemistry Letters 52, pages 92-103.
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Wagner Barbosa Da Rocha Santos, Juliana Oliveira Guimarães, Lícia Tairiny Santos Pina, Mairim Russo Serafini & Adriana Gibara Guimarães. (2022) Antinociceptive effect of plant-based natural products in chemotherapy-induced peripheral neuropathies: A systematic review. Frontiers in Pharmacology 13.
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Li-Yu Wang, Shu-Lan Yeh, Shih-Tien Hsu, Chao-Hsiang Chen, Chien-Chih Chen & Cheng-Hung Chuang. (2022) The Anti-Proliferative and Apoptotic Effects of Rutaecarpine on Human Esophageal Squamous Cell Carcinoma Cell Line CE81T/VGH In Vitro and In Vivo. International Journal of Molecular Sciences 23:5, pages 2843.
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Wei Zhang, Kun Ren, Shuangfeng Wu, Jingyan Guo, Shumeng Ren, Yingni Pan, Dongmei Wang, Toshio Morikawa, Huiming Hua & Xiaoqiu Liu. (2021) Cytotoxicity evaluation and metabolism of hepatotoxicity components of Euodiae Fructus in L02 cells. Journal of Chromatography B 1186, pages 123040.
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Yutao Liu, Chang Liu, Yamei Liu, Quanli Ge & Chen Sun. (2020) Cytochrome P450 Mediated Bioactivation of Rutaevin, a Bioactive and Potentially Hepatotoxic Component of Evodia Rutaecarpa . Chemical Research in Toxicology 33:12, pages 3054-3064.
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Manlin Li & Changhong Wang. (2020) Traditional uses, phytochemistry, pharmacology, pharmacokinetics and toxicology of the fruit of Tetradium ruticarpum: A review. Journal of Ethnopharmacology 263, pages 113231.
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Xiaojiaoyang Li, Junde Ge, Qi Zheng, Jiaxiang Zhang, Rong Sun & Runping Liu. (2020) Evodiamine and rutaecarpine from Tetradium ruticarpum in the treatment of liver diseases. Phytomedicine 68, pages 153180.
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Jinjin Ma, Lan Chen, Jinbao Fan, Wei Cao, Guangyao Zeng, Yajing Wang, Yuanjian Li, Yingjun Zhou & Xu Deng. (2019) Dual-targeting Rutaecarpine-NO donor hybrids as novel anti-hypertensive agents by promoting release of CGRP. European Journal of Medicinal Chemistry 168, pages 146-153.
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Zefeng Zhao, Xirui He, Wei Han, Xufei Chen, Peiliang Liu, Xue Zhao, Xing Wang, Lixin Zhang, Shaoping Wu & Xiaohui Zheng. (2019) Genus Tetradium L.: A comprehensive review on traditional uses, phytochemistry, and pharmacological activities. Journal of Ethnopharmacology 231, pages 337-354.
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Zi-Xuan Wang, Jia-Chen Xiang, Miao Wang, Jin-Tian Ma, Yan-Dong Wu & An-Xin Wu. (2018) One-Pot Total Synthesis of Evodiamine and Its Analogues through a Continuous Biscyclization Reaction. Organic Letters 20:20, pages 6380-6383.
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Cuiyun Wang, Fang Yue, Guangfeng Ai & Jie Yang. (2018) Simultaneous determination of evodiamine and its four metabolites in rat plasma by LC-MS/MS and its application to a pharmacokinetic study. Biomedical Chromatography 32:7, pages e4219.
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Le Shi, Fan Yang, Fei Luo, Yi Liu, Feng Zhang, Meijuan Zou & Qizhan Liu. (2016) Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis. Tumor Biology 37:9, pages 12791-12803.
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Huarong Xu, Yajing Geng, Ran Liu, Ziyue Yuan, Xujia Liu, Qing Li & Kaishun Bi. (2016) Qualitative screening of absorbed indoloquinazoline alkaloids and their metabolites in rat plasma after the oral administration of Wu-Zhu-Yu decoction by high-resolution mass spectrometry with multiple data mining algorithms. Journal of Separation Science 39:16, pages 3260-3266.
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Eun-Tae Oh, Ji-Ho Lee, Chang-Soo Kim & Young-Soo Keum. (2014) Alkylquinolone alkaloid profiles in Ruta graveolens. Biochemical Systematics and Ecology 57, pages 384-387.
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Bo Wen, Vikram Roongta, Liling Liu & David J. Moore. (2014) Metabolic Activation of the Indoloquinazoline Alkaloids Evodiamine and Rutaecarpine by Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4. Drug Metabolism and Disposition 42:6, pages 1044-1054.
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Duyeol Kim, Yong-Hoon Lee, Sun Hee Park, Mi Ju Lee, Myoung Jun Kim, Ho-Song Jang, Jung-Min Lee, Hye-Yeong Lee, Beom Seok Han, Woo-Chan Son, Ji Hyeon Seok, Jong Kwon Lee, Jayoung Jeong, Jin Seok Kang & Jong-Koo Kang. (2014) Subchronic oral toxicity of evodia fruit powder in rats. Journal of Ethnopharmacology 151:3, pages 1072-1078.
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Maria Fátima das Graças Fernandes da Silva, João Batista Fernandes, Moacir Rossi Forim, Paulo Cezar Vieira & Israel Cívico Gil de Sá. 2013. Natural Products. Natural Products 715 859 .
Guoqiang Dong, Shengzheng Wang, Zhenyuan Miao, Jianzhong Yao, Yongqiang Zhang, Zizhao Guo, Wannian Zhang & Chunquan Sheng. (2012) New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations. Journal of Medicinal Chemistry 55:17, pages 7593-7613.
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Xin Huang, Wei Li & Xiu-Wei Yang. (2012) New cytotoxic quinolone alkaloids from fruits of Evodia rutaecarpa. Fitoterapia 83:4, pages 709-714.
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Shuo-Guo Li, Hai-Yan Tian, Wei-Cai Ye & Ren-Wang Jiang. (2011) Benzopyrans and furoquinoline alkaloids from Melicope pteleifolia. Biochemical Systematics and Ecology 39:1, pages 64-67.
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Hye-Min Park, Mi-Won Son, Dong-Hyun Kim, Seon-Hee Kim, Sung-Hoon Kim, Hak-Cheol Kwon & Sun-Yeou Kim. (2011) Fatty Acid Components of Hardy Kiwifruit (Actinidia arguta) as IL-4 Production Inhibitor. Biomolecules and Therapeutics 19:1, pages 126-133.
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Sung-Hou Lee. (2011) Platform Technologies for Research on the G Protein Coupled Receptor: Applications to Drug Discovery Research. Biomolecules and Therapeutics 19:1, pages 1-8.
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Hongwei YU, Bogang LI, Xiaozhen Chen, Changsong LI & Guolin ZHANG. (2010) Chemical Study on <I>Evodia vestita</I><SUP>*</SUP>. Chinese Journal of Appplied Environmental Biology 16:1, pages 72-75.
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Meng-yao Zhao & Xiu-wei Yang. (2008) Optimization of the Extraction Conditions and Simultaneous Quantification by RP-LC of Six Alkaloids in Evodiae Fructus. Chromatographia 67:7-8, pages 543-550.
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