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Journal of Asian Natural Products Research Volume 8, 2006 - Issue 7
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Original Articles

Effect of 17β-oestradiol and ginsenoside on osteoporosis in ovariectomised rats

Y.-S. Gong Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China
,
J. Chen Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China
,
Q.-Z. Zhang Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China
&
J.-T. Zhang Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, ChinaCorrespondence[email protected]
Pages 649-656 | Received 12 Jan 2005, Accepted 23 May 2005, Published online: 01 Dec 2006

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Yanhai Xi, Weiheng Wang, Liang Ma, Ning Xu, Changgui Shi, Guohua Xu, Hailong He & Wenming Pan. (2022) Alendronate modified mPEG-PLGA nano-micelle drug delivery system loaded with astragaloside has anti-osteoporotic effect in rats. Drug Delivery 29:1, pages 2386-2402.
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Chun Shi, Ning Na, Xiaoming Zhu & Jie Xu. (2013) Estrogenic effect of Ginsenoside Rg1 on APP processing in post-menopausal platelets. Platelets 24:1, pages 51-62.
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Articles from other publishers (28)

Seyedeh Mahnaz Karimi, Mohammad Bayat & Roja Rahimi. (2023) Plant-derived natural medicines for the management of osteoporosis: A comprehensive review of clinical trials. Journal of Traditional and Complementary Medicine.
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Wenhui Chen, Xinyan Jin, Ting Wang, Rui Bai, Jun Shi, Yunxia Jiang, Simin Tan, Ruijie Wu, Shiqi Zeng, Hongxiang Zheng, Hongyang Jia & Shuanglei Li. (2022) Ginsenoside Rg1 interferes with the progression of diabetic osteoporosis by promoting type H angiogenesis modulating vasculogenic and osteogenic coupling. Frontiers in Pharmacology 13.
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Sen Zhang, Shihong Shen, Pei Ma & Daidi Fan. (2022) Biochemical Targets and Molecular Mechanism of Ginsenoside Compound K in Treating Osteoporosis Based on Network Pharmacology. International Journal of Molecular Sciences 23:22, pages 13921.
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Dan Zhang, Jian Du, Min Yu & Linna Suo. (2022) Ginsenoside Rb1 prevents osteoporosis via the AHR/PRELP/NF-κB signaling axis. Phytomedicine 104, pages 154205.
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Yong-In Ju, Hak-Jin Choi & Teruki Sone. (2022) Effects of Korean red ginseng on three-dimensional trabecular bone microarchitecture and strength in growing rats: Comparison with changes due to jump exercise. PLOS ONE 17:5, pages e0267466.
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Adithan Aravinthan, Mohammad Amjad Hossain, Bumseok Kim, Chang-Won Kang, Nam Soo Kim, Ki-Chul Hwang & Jong-Hoon Kim. (2021) Ginsenoside Rb1 inhibits monoiodoacetate-induced osteoarthritis in postmenopausal rats through prevention of cartilage degradation. Journal of Ginseng Research 45:2, pages 287-294.
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Fang Wang, Zhiyong Yang, Wei He, Qinggao Song, Kun Wang & Yali Zhou. (2020) Effects of icariin on the proliferation and osteogenic differentiation of human amniotic mesenchymal stem cells. Journal of Orthopaedic Surgery and Research 15:1.
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In Soon Kang, Taiwo Samuel Agidigbi, Young Min Kwon, Dong-Gyu Kim, Rang Ie Kim, Gyo In, Mi-Hyang Lee & Chaekyun Kim. (2020) Effect of Co-Administration of Panax ginseng and Brassica oleracea on Postmenopausal Osteoporosis in Ovariectomized Mice. Nutrients 12:8, pages 2415.
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Xin Sun, Bo Wei, Zhiheng Peng, Xiaru Chen, Qinglong Fu, Chaojun Wang, Jinchang Zhen & Jiecong Sun. (2020) A polysaccharide from the dried rhizome of Drynaria fortunei (Kunze) J. Sm. prevents ovariectomized (OVX)‐induced osteoporosis in rats. Journal of Cellular and Molecular Medicine 24:6, pages 3692-3700.
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Yi-Qing Wang, Nuo-Xin Wang, Yi Luo, Chang-Yin Yu & Jian-Hui Xiao. (2020) Ganoderal A effectively induces osteogenic differentiation of human amniotic mesenchymal stem cells via cross-talk between Wnt/β-catenin and BMP/SMAD signaling pathways. Biomedicine & Pharmacotherapy 123, pages 109807.
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Bianca Neofiti-PapiRuda P. AlbuquerqueManuela Miranda-RodriguesNatalia J.N. GonçalvesVanda JorgettiPatricia C. BrumJulio C.B. FerreiraCecilia H.A. Gouveia. (2019) Thyrotoxicosis Involves β2-Adrenoceptor Signaling to Negatively Affect Microarchitecture and Biomechanical Properties of the Femur. Thyroid 29:8, pages 1060-1072.
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Seungyeop Lee & Dong-Kwon Rhee. (2017) Effects of ginseng on stress-related depression, anxiety, and the hypothalamic–pituitary–adrenal axis. Journal of Ginseng Research 41:4, pages 589-594.
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Young-Gon Sun, Young-Tae Kim, Xing-Hui Piao, Jong-Wook Moon & Young-Joon Kim. (2017) The effect of a novel botanical agent on early osteogenic response of osteoblasts. Oral Biology Research 41:2, pages 69-74.
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Seyedramin Pajoumshariati, Seyedeh Kimia Yavari & Mohammad Ali Shokrgozar. (2015) Physical and Biological Modification of Polycaprolactone Electrospun Nanofiber by Panax Ginseng Extract for Bone Tissue Engineering Application. Annals of Biomedical Engineering 44:5, pages 1808-1820.
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Chun-Tao Che, Man Wong & Christopher Lam. (2016) Natural Products from Chinese Medicines with Potential Benefits to Bone Health. Molecules 21:3, pages 239.
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Jing-Zheng Fan, Yi Wang, Yan Meng, Guan-Wu Li, Shi-Xin Chang, Hua Nian & Yong-Jie Liang. (2015) Panax notoginseng saponins mitigate ovariectomy-induced bone loss and inhibit marrow adiposity in rats. Menopause 22:12, pages 1343-1350.
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Lihui Li, Xi Chen, Shuang Lv, Miaomiao Dong, Li Zhang, Jiaheng Tu, Jie Yang, Lingli Zhang, Yinan Song, Leiting Xu & Jun Zou. (2014) Influence of Exercise on Bone Remodeling-Related Hormones and Cytokines in Ovariectomized Rats: A Model of Postmenopausal Osteoporosis. PLoS ONE 9:11, pages e112845.
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Miyoung Yang, Hyosun Jang, Hae-June Lee, Changjong Moon, Jong-Choon Kim, Jong-Sik Jang, Uhee Jung, Sung-Kee Jo & Sung-Ho Kim. (2014) Evaluation of effect of red ginseng on ovariectomy-induced bone loss in C3H/HeN mice. Journal of Biomedical Research 15:1, pages 12-18.
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Ping Wang, Xi Wei, Fujun Zhang, Kai Yang, Chen Qu, Huiqiong Luo & Longzhu He. (2014) Ginsenoside Rg1 of Panax ginseng stimulates the proliferation, odontogenic/osteogenic differentiation and gene expression profiles of human dental pulp stem cells. Phytomedicine 21:2, pages 177-183.
Crossref
Muhammad Hanif Siddiqi, Muhammad Zubair Siddiqi, Sungeun Ahn, Sera Kang, Yeon-Ju Kim, Natarajan Sathishkumar, Dong-Uk Yang & Deok-Chun Yang. (2013) Ginseng saponins and the treatment of osteoporosis: mini literature review. Journal of Ginseng Research 37:3, pages 261-268.
Crossref
P Wang, X Wei, Y Zhou, Y-P Wang, K Yang, F-J Zhang & R Jiang. (2012) Effect of ginsenoside Rg1 on proliferation and differentiation of human dental pulp cells in vitro. Australian Dental Journal 57:2, pages 157-165.
Crossref
Binbin Cheng, Jun Li, Juan Du, Xiang Lv, Li Weng & Changquan Ling. (2012) Ginsenoside Rb1 inhibits osteoclastogenesis by modulating NF-κB and MAPKs pathways. Food and Chemical Toxicology 50:5, pages 1610-1615.
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Chun Shi, Dong-dan Zheng, Li Fang, Fengming Wu, Wing Hang Kwong & Jie Xu. (2012) Ginsenoside Rg1 promotes nonamyloidgenic cleavage of APP via estrogen receptor signaling to MAPK/ERK and PI3K/Akt. Biochimica et Biophysica Acta (BBA) - General Subjects 1820:4, pages 453-460.
Crossref
Paul Goetz, Patrick Stoltz & Dominique DelaportePaul Goetz. 2012. Il ginseng. Il ginseng 47 93 .
Xue-dong Li, Zhao-yong Liu, Bo Chang, Dong-xin Liu, Bin Chen, Chun Guo, Yun-guo Wang, Jian-kun Xu, Dong-yang Huang & Shi-xin Du. (2011) <i>Panax Notoginseng</i> Saponins Promote Osteogenic Differentiation of Bone Marrow Stromal Cells Through the ERK and P38 MAPK Signaling Pathways. Cellular Physiology and Biochemistry 28:2, pages 367-376.
Crossref
Yang Shen, Yong-Qi Li, Shao-Ping Li, Lin Ma, Li-Ju Ding & Hui Ji. (2010) Alleviation of ovariectomy-induced osteoporosis in rats by Panax notoginseng saponins. Journal of Natural Medicines 64:3, pages 336-345.
Crossref
Xue-dong Li, Bo Chang, Bin Chen, Zhao-yong Liu, Dong-xin Liu, Jian-sheng Wang, Guo-qing Hou, Dong-yang Huang & Shi-xin Du. (2010) <i>Panax notoginseng</i> Saponins Potentiate Osteogenesis of Bone Marrow Stromal Cells by Modulating Gap Junction Intercellular Communication Activities. Cellular Physiology and Biochemistry 26:6, pages 1081-1092.
Crossref
Paul Goetz, Dominique Delaporte & Patrick StoltzP. Goetz. 2009. Le Ginseng. Le Ginseng 61 114 .

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