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Journal of Asian Natural Products Research Volume 10, 2008 - Issue 10
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Original Articles

Microbial transformation of alantolactone by Mucor polymorphosporus

Xiu-Lan Xin The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China; Beijing Vocational College of Electronic Science and Technology, Biotechnology Application Center, Beijing, China
,
Xiao-Chi Ma School of Pharmaceutical Sciences, Dalian Medical University, Dalian, ChinaCorrespondence[email protected]
,
Ke-Xin Liu School of Pharmaceutical Sciences, Dalian Medical University, Dalian, China
,
Jian Han The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
,
Bao-Rong Wang The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
&
De-An Guo The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
Pages 933-937 | Received 18 Dec 2007, Accepted 03 May 2008, Published online: 11 Nov 2008

Citations (14)

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Nurul Iman Aminudin, Munirah Ridzuan, Deny Susanti & Zaima Azira Zainal Abidin. (2022) Biotransformation of sesquiterpenoids: a recent insight. Journal of Asian Natural Products Research 24:2, pages 103-145.
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Articles from other publishers (13)

Xin Liu, Lijuan Bian, Xiaoqin Duan, Xinming Zhuang, Yujie Sui & Longfei Yang. (2021) Alantolactone: A sesquiterpene lactone with diverse pharmacological effects. Chemical Biology & Drug Design 98:6, pages 1131-1145.
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Xiaoqin Zheng, Zi Wu, Jie Xu, Xinxin Zhang, Yijun Tu, Jiachuan Lei, Ruiying Yuan, Haitao Cheng, Qiang Wang & Jianqing Yu. (2021) Bioactive sesquiterpenes from Inula helenium. Bioorganic Chemistry 114, pages 105066.
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Wen-Ho Chuo, Yu-Tang Tung, Chao-Liang Wu, Nicole R. Bracci, Yu-Kang Chang, Hung-Yi Huang & Chi-Chien Lin. (2021) Alantolactone Suppresses Proliferation and the Inflammatory Response in Human HaCaT Keratinocytes and Ameliorates Imiquimod-Induced Skin Lesions in a Psoriasis-Like Mouse Model. Life 11:7, pages 616.
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Jin‐Shan Xing, Xun Wang, Yu‐Long Lan, Jia‐Cheng Lou, Binbin Ma, Tingzhun Zhu, Hongqiang Zhang, Dongsheng Wang, Zhikuan Yu, Zhongbo Yuan, Xin‐Yu Li & Bo Zhang. (2019) Isoalantolactone inhibits IKKβ kinase activity to interrupt the NF‐κB/COX‐2‐mediated signaling cascade and induces apoptosis regulated by the mitochondrial translocation of cofilin in glioblastoma. Cancer Medicine 8:4, pages 1655-1670.
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Xiaohe Li, Cheng Lu, Shuangwei Liu, shuaishuai Liu, Chengcheng Su, Ting Xiao, Zhun Bi, Pengzhen Sheng, Mengying Huang, Xinhua Liu, Yujiao Wei, Lin Zhao, Shengxiang Miao, Jiahe Mao, Kai Huang, Shaoyan Gao, Ning Liu, Min Qi, Tongtong Liu, Shuanglin Qin, Luqing Wei, Tao Sun, Wen Ning, Guang Yang, Honggang Zhou & Cheng Yang. (2018) Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway. European Journal of Medicinal Chemistry 157, pages 229-247.
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Donggui Yao, Zhe Li, Changhong Huo, Yufang Wang, Yibing Wu, Manli Zhang, Ligeng Li, Qingwen Shi, Hiromasa Kiyota & Xiaowei Shi. (2016) Identification of in vitro and in vivo metabolites of alantolactone by UPLC-TOF-MS/MS. Journal of Chromatography B 1033-1034, pages 250-260.
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Chong-Zhen Qin, Qiao-Li Lv, Na-Yiyuan Wu, Lin Cheng, Yun-Chen Chu, Tang-Yuan Chu, Lei Hu, Yu Cheng, Xue Zhang & Hong-Hao Zhou. (2015) Mechanism-based inhibition of Alantolactone on human cytochrome P450 3A4 in vitro and activity of hepatic cytochrome P450 in mice. Journal of Ethnopharmacology 168, pages 146-149.
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Renjie Xu, Guisheng Zhou, Ying Peng, Mengyue Wang & Xiaobo Li. (2015) Pharmacokinetics, Tissue Distribution and Excretion of Isoalantolactone and Alantolactone in Rats after Oral Administration of Radix Inulae Extract. Molecules 20:5, pages 7719-7736.
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Li-Xia Chen, Qian Zhao, Meng Zhang, Yan-Yan Liang, Jiang-Hao Ma, Xue Zhang, Li-Qin Ding, Feng Zhao & Feng Qiu. (2015) Biotransformation of Curcumenol by Mucor polymorphosporus . Journal of Natural Products 78:4, pages 674-680.
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Faya M. Millimouno, Jia Dong, Liu Yang, Jiang Li & Xiaomeng Li. (2014) Targeting Apoptosis Pathways in Cancer and Perspectives with Natural Compounds from Mother Nature. Cancer Prevention Research 7:11, pages 1081-1107.
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Renjie Xu, Mengyue Wang, Ying Peng & Xiaobo Li. (2014) Pharmacokinetic Comparison of Isoalantolactone and Alantolactone in Rats after Administration Separately by Optimization of an UPLC-MS 2 Method . Journal of Chemistry 2014, pages 1-8.
Crossref
Azhar Rasul, Muhammad Khan, Muhammad Ali, Jiang Li & Xiaomeng Li. (2013) Targeting Apoptosis Pathways in Cancer with Alantolactone and Isoalantolactone. The Scientific World Journal 2013, pages 1-9.
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Braulio M. Fraga. (2009) Natural sesquiterpenoids. Natural Product Reports 26:9, pages 1125.
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