259
Views
27
CrossRef citations to date
0
Altmetric
Original Articles

Inhibitory effects of sesquiterpenes from Saussurea lappa on the overproduction of nitric oxide and TNF-α release in LPS-activated macrophages

, , , &
Pages 1045-1053 | Received 09 Jan 2008, Accepted 26 May 2008, Published online: 22 Nov 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Pablo A. Chacón-Morales, Carolina Santiago Dugarte & Juan M. Amaro-Luis. (2021) Helenin from Stevia lucida. The first report of this natural eudesmanolide mixture in Eupatorieae tribe. Natural Product Research 35:21, pages 4139-4142.
Read now
Vinod Prabhu & C. Guruvayoorappan. (2010) Nitric oxide: pros and cons in tumor progression. Immunopharmacology and Immunotoxicology 32:3, pages 387-392.
Read now

Articles from other publishers (25)

Ebraheem Abouelwafa, Amal Zaki, Omar M. Sabry, Giovanni Caprioli & Essam Abdel-Sattar. (2023) Dolomiaea costus: an untapped mine of sesquiterpene lactones with wide magnificent biological activities . Natural Product Research 37:23, pages 4069-4079.
Crossref
Tao Liu, Minghui Dai, Hai Zhu, Yanling Huang, Jiming Chen, Menghe Li, Yuying Guo, Chen Huang, Caiwenjie La, Zui Wang, Zhiping Wang, Zhe Ren, Cuifang Ye, Xinglong Zheng & Yifei Wang. (2023) Activity-guided isolation and identification of antiherpesvirus and antineuroinflammatory active terpenoids from Artemisia vulgaris L. based on the LC-MS/MS molecular network. Phytochemistry 216, pages 113863.
Crossref
Shuangyu Xu, Yunyan Tang, Yanan Li, Jue Yang, Wei Gu, Xiaojiang Hao & Chunmao Yuan. (2023) Discovery of diverse sesquiterpenoids from Magnolia grandiflora with cytotoxic activities by inducing cell apoptosis. Bioorganic Chemistry 139, pages 106707.
Crossref
Jargalsaikhan Gombodorj, Enkhjargal Bayarsaikhan, Chimedragchaa Chimedtseren, Uuganbayar Baatartsogt, Lhagva-Ochir Tovuu, Anu Altangerel, Lagshmaa Baldoo & Seesregdorj Surenjid. (2023) The study of the Mongolian traditional medicine Khurtsiin deed-6 analgesic and anti-inflammatory effect by inhibiting glial cell activation in nitroglycerin-induced migraine in rats. Phytomedicine Plus 3:1, pages 100388.
Crossref
Kaiyan Zhuang, Qing Xia, Shanshan Zhang, Kannan Maharajan, Kechun Liu & Yun Zhang. (2021) A comprehensive chemical and pharmacological review of three confusable Chinese herbal medicine—Aucklandiae radix, Vladimiriae radix, and Inulae radix. Phytotherapy Research 35:12, pages 6655-6689.
Crossref
Hee-Geun Jo, Geon-Yeong Lee, Chae Yun Baek, Ho Sueb Song & Donghun Lee. (2020) Analgesic and Anti-Inflammatory Effects of Aucklandia lappa Root Extracts on Acetic Acid-Induced Writhing in Mice and Monosodium Iodoacetate-Induced Osteoarthritis in Rats. Plants 10:1, pages 42.
Crossref
Rohit Kumar Nadda, Aaliya Ali, Renu Chib Goyal, Prem Kumar Khosla & Rohit Goyal. (2020) Aucklandia costus (Syn. Saussurea costus): Ethnopharmacology of an endangered medicinal plant of the himalayan region. Journal of Ethnopharmacology 263, pages 113199.
Crossref
Ali A. Shati, Mohammed A. Alkahtani, Mohamed Y. Alfaifi, Serag Eldin I. Elbehairi, Fahmy G. Elsaid, Rajagopalan Prasanna & Mushtaq A. Mir. (2020) Secondary Metabolites of Saussurea costus Leaf Extract Induce Apoptosis in Breast, Liver, and Colon Cancer Cells by Caspase-3-Dependent Intrinsic Pathway . BioMed Research International 2020, pages 1-11.
Crossref
Shahid AkbarShahid Akbar. 2020. Handbook of 200 Medicinal Plants. Handbook of 200 Medicinal Plants 1609 1617 .
Siwattra Choodej, Khanitha Pudhom, Kosei Yamauchi & Tohru Mitsunaga. (2019) Inhibition of melanin production by sesquiterpene lactones from Saussurea lappa and their analogues. Medicinal Chemistry Research 28:6, pages 857-862.
Crossref
Qian-Wen Yang, Qiao Li, Jie Zhang, Qian Xu, Xin Yang, Zhi-Yong Li & Hui Xu. (2019) Crystal structure and anti-inflammatory and anaphylactic effects of andrographlide sulphonate E in Xiyanping, a traditional Chinese medicine injection. Journal of Pharmacy and Pharmacology 71:2, pages 251-259.
Crossref
Qian Zhang, Ruiling Luan, Huixiang Li, Yanan Liu, Pan Liu, Liying Wang, Danna Li, Mengdi Wang, Qiang Zou, Hongwei Liu, Keiichi Matsuzaki & Feng Zhao. (2018) Anti‑inflammatory action of ambuic acid, a natural product isolated from the solid culture of Pestalotiopsis�neglecta, through blocking ERK/JNK mitogen‑activated protein kinase signaling pathway. Experimental and Therapeutic Medicine.
Crossref
Melanie-Jayne R. Howes. 2018. Immunity and Inflammation in Health and Disease. Immunity and Inflammation in Health and Disease 363 388 .
Huixiang Li, Qian Zhang, Xin Jin, Xiaowen Zou, Yuexuan Wang, Dexiang Hao, Fenghua Fu, Weihua Jiao, Cuixia Zhang, Houwen Lin, Keiichi Matsuzaki & Feng Zhao. (2017) Dysifragilone A inhibits LPS‑induced RAW264.7 macrophage activation by blocking the p38 MAPK signaling pathway. Molecular Medicine Reports.
Crossref
Donggui Yao, Yufang Wang, Changhong Huo, Yibing Wu, Manli Zhang, Ligeng Li, Qingwen Shi, Hiromasa Kiyota & Xiaowei Shi. (2017) Study on the metabolites of isoalantolactone in vivo and in vitro by ultra performance liquid chromatography combined with Triple TOF mass spectrometry. Food Chemistry 214, pages 328-338.
Crossref
XIN JIN, JUNJIE HAN, SHUXIAN YANG, YUAN HU, HONGWEI LIU & FENG ZHAO. (2016) 11-O-acetylcyathatriol inhibits MAPK/p38-mediated inflammation in LPS-activated RAW 264.7 macrophages and has a protective effect on ethanol-induced gastric injury. Molecular Medicine Reports 14:1, pages 874-880.
Crossref
XIN JIN, SHIQING SONG, JING WANG, QINGZHEN ZHANG, FENG QIU & FENG ZHAO. (2016) Tiliroside, the major component of Agrimonia pilosa Ledeb ethanol extract, inhibits MAPK/JNK/p38-mediated inflammation in lipopolysaccharide-activated RAW 264.7 macrophages. Experimental and Therapeutic Medicine 12:1, pages 499-505.
Crossref
Xin Jin, Jing Wang, Zi-Ming Xia, Chang-Hui Shang, Qiu-Li Chao, Ya-Ru Liu, Hua-Ying Fan, Da-Quan Chen, Feng Qiu & Feng Zhao. (2015) Anti-inflammatory and Anti-oxidative Activities of Paeonol and Its Metabolites Through Blocking MAPK/ERK/p38 Signaling Pathway. Inflammation 39:1, pages 434-446.
Crossref
Kulsoom Zahara, Shaista Tabassum, Sidra Sabir, Muhammad Arshad, Rahmatullah Qureshi, Muhammad Shoaib Amjad & Sunbal Khalil Chaudhari. (2014) A review of therapeutic potential of Saussurea lappa-An endangered plant from Himalaya. Asian Pacific Journal of Tropical Medicine 7, pages S60-S69.
Crossref
Seong Woo Yoon, Jong Soo Jeong, Ji Hye Kim & Bharat B. Aggarwal. (2013) Cancer Prevention and Therapy. Integrative Cancer Therapies 13:4, pages 310-331.
Crossref
Maurizio Bruno, Svetlana Bancheva, Sergio Rosselli & Antonella Maggio. (2013) Sesquiterpenoids in subtribe Centaureinae (Cass.) Dumort (tribe Cardueae, Asteraceae): Distribution, 13C NMR spectral data and biological properties. Phytochemistry 95, pages 19-93.
Crossref
Huaying Fan, Dong Qi, Mingyan Yang, Hui Fang, Ke Liu & Feng Zhao. (2013) In vitro and in vivo anti-inflammatory effects of 4-methoxy-5- hydroxycanthin-6-one, a natural alkaloid from Picrasma quassioides. Phytomedicine 20:3-4, pages 319-323.
Crossref
Songhee Jeon, Jinyoung Hur, Ha Jin Jeong, Byung-Soo Koo & Sok Cheon Pak. (2012) SuHeXiang Wan Essential Oil Alleviates Amyloid Beta Induced Memory Impairment Through Inhibition of Tau Protein Phosphorylation in Mice. The American Journal of Chinese Medicine 39:05, pages 917-932.
Crossref
Agnieszka Zabłocka, Antoni Ogorzałek, Józefa Macała & Maria Janusz. (2010) A proline-rich polypeptide complex (PRP) influences inducible nitric oxide synthase in mice at the protein level. Nitric Oxide 23:1, pages 20-25.
Crossref
Braulio M. Fraga. (2009) Natural sesquiterpenoids. Natural Product Reports 26:9, pages 1125.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.