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Journal of Asian Natural Products Research Volume 10, 2008 - Issue 11
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Original Articles

An effective O-demethylation of some C19-diterpenoid alkaloids with HBr–glacial acetic acid

Chun-Lan Zou Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, China
,
Hong Ji Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, China
,
Guang-Bo Xie Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, China
,
Dong-Lin Chen Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, China
&
Feng-Peng Wang Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, ChinaCorrespondence[email protected]
Pages 1063-1067 | Received 21 Jan 2008, Accepted 26 May 2008, Published online: 22 Nov 2008

Citations (15)

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Aamer Saeed & Muhammad Qasim. (2014) An efficient total synthesis of trilepisiumic acid. Natural Product Research 28:14, pages 1121-1126.
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Aamer Saeed & Muhammad Qasim. (2014) Total synthesis of cytotoxic metabolite ( ± )-desmethyldiaportinol from Ampelomyces sp.. Natural Product Research 28:3, pages 185-190.
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Meng Zhu, Xiao-Yu Liu, Qiao-Hong Chen & Feng-Peng Wang. (2012) Biomimetic conversion of aconitine-type C19-diterpenoid alkaloids to lactone-type alkaloids. Journal of Asian Natural Products Research 14:5, pages 441-449.
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Xiao-Xia Liang, Qiao-Hong Chen & Feng-Peng Wang. (2011) Regioselective O-demethylation of two C19-diterpenoid alkaloids. Journal of Asian Natural Products Research 13:7, pages 624-633.
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Articles from other publishers (11)

Xiaojie Li, Jifa Zhang, Qifeng Chen, Pan Tang, Ting Zhang, Qiyi Feng, Jiajun Chen, Yun Liu, Feng-Peng Wang, Cheng Peng, Yong Qin, Liang Ouyang, Kai Xiao & Xiao-Yu Liu. (2023) Diversity-oriented synthesis of diterpenoid alkaloids yields a potent anti-inflammatory agent. Phytomedicine 117, pages 154907.
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Achyut Dahal, Mary Lo, Sitanshu Singh, Huu Vo, Denzel ElHage, Seetharama D. Jois & Siva Murru. (2022) 1,3‐diarylpyrazolones as potential anticancer agents for non‐small cell lung cancer: Synthesis and antiproliferative activity evaluation. Chemical Biology & Drug Design 99:4, pages 620-633.
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Weiguo Xiang, Shruti Choudhary, Ernest Hamel, Susan L. Mooberry & Aleem Gangjee. (2018) Structure based drug design and in vitro metabolism study: Discovery of N-(4-methylthiophenyl)-N,2-dimethyl-cyclopenta[d]pyrimidine as a potent microtubule targeting agent. Bioorganic & Medicinal Chemistry 26:9, pages 2437-2451.
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Hua Tang, Qi-Feng Chen, Xiao-Yu Liu, Hua Zhang, Dong-Lin Chen & Feng-Peng Wang. (2016) Novel analogues of diterpenoid alkaloids from ring distortion of talatisamine, a potassium ion channel blocker. Tetrahedron 72:10, pages 1357-1363.
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Qi-Feng Chen, Feng-Peng Wang & Xiao-Yu Liu. (2015) Generating Skeletal Diversity from the C 19 -Diterpenoid Alkaloid Deltaline: A Ring-Distortion Approach . Chemistry - A European Journal 21:24, pages 8946-8950.
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Zhongduo Yang, Zhuwen Song, Weiwei Xue, Jie Sheng, Zongmei Shu, Yin Shi, Jibei Liang & Xiaojun Yao. (2014) Synthesis and structure–activity relationship of nuciferine derivatives as potential acetylcholinesterase inhibitors. Medicinal Chemistry Research 23:6, pages 3178-3186.
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Pei Tang, Qi-Feng Chen, Ling Wang, Qiao-Hong Chen, Xi-Xian Jian & Feng-Peng Wang. (2012) New reactivities of deltaline analogs: an efficient O-demethylation at C-1 and an unusual extrusion of the C-14 atom. Tetrahedron 68:27-28, pages 5668-5676.
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Xiao-Xia Liang, Pei Tang, Qiao-Hong Chen & Feng-Peng Wang. (2012) Synthesis of Taxane ABC Tricyclic Skeleton from Lycoctonine. Natural Product Communications 7:6, pages 1934578X1200700.
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Pei Tang, Ling Wang, Qi-Feng Chen, Qiao-Hong Chen, Xi-Xian Jian & Feng-Peng Wang. (2012) Novel reactions of a deltaline analog: an unusual skeletal rearrangement of E/F ring system. Tetrahedron 68:25, pages 5031-5036.
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Feng-Peng Wang, Qiao-Hong Chen & Xiao-Yu Liu. (2010) Diterpenoid alkaloids. Natural Product Reports 27:4, pages 529.
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Feng-Peng Wang & Qiao-Hong Chen. 2010. 1 577 .

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