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Research Article

Polyadenylate Polymerase (PAP) and 3' End pre-mRNA Processing: Function, Assays, and Association with Disease

Pages 193-224 | Published online: 29 Sep 2008

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Ana Curinha, Sandra Oliveira Braz, Isabel Pereira-Castro, Andrea Cruz & Alexandra Moreira. (2014) Implications of polyadenylation in health and disease. Nucleus 5:6, pages 508-519.
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Articles from other publishers (21)

A P Sudheesh, Nimmy Mohan, Nimmy Francis, Rakesh S Laishram & Richard A Anderson. (2019) Star-PAP controlled alternative polyadenylation coupled poly(A) tail length regulates protein expression in hypertrophic heart. Nucleic Acids Research 47:20, pages 10771-10787.
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Xiaoxiao Wang, Mark Milne, Francisco Martínez, Timothy J. Scholl & Robert H. E. Hudson. (2017) Synthesis of a poly(Gd( iii )-DOTA)–PNA conjugate as a potential MRI contrast agent via post-synthetic click chemistry functionalization . RSC Advances 7:71, pages 45222-45226.
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Ranjan Batra, Thomas J Stark, Alex E. Clark, Jean-Philippe Belzile, Emily C Wheeler, Brian A Yee, Hui Huang, Chelsea Gelboin-Burkhart, Stephanie C Huelga, Stefan Aigner, Brett T Roberts, Tomas J Bos, Shashank Sathe, John Paul Donohue, Frank Rigo, Manuel AresJrJr, Deborah H Spector & Gene W Yeo. (2016) RNA-binding protein CPEB1 remodels host and viral RNA landscapes. Nature Structural & Molecular Biology 23:12, pages 1101-1110.
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Ayse Elif Erson-Bensan & Tolga Can. (2016) Alternative Polyadenylation: Another Foe in Cancer. Molecular Cancer Research 14:6, pages 507-517.
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Fabian Afonso-Grunz & Sören Müller. (2015) Principles of miRNA–mRNA interactions: beyond sequence complementarity. Cellular and Molecular Life Sciences 72:16, pages 3127-3141.
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Aimee L. Jalkanen, Stephen J. Coleman & Jeffrey Wilusz. (2014) Determinants and implications of mRNA poly(A) tail size – Does this protein make my tail look big?. Seminars in Cell & Developmental Biology 34, pages 24-32.
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Annika Scior, Steffen Preissler, Miriam Koch & Elke Deuerling. (2011) Directed PCR-free engineering of highly repetitive DNA sequences. BMC Biotechnology 11:1.
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F I Nazeer, E Devany, S Mohammed, D Fonseca, B Akukwe, C Taveras & F E Kleiman. (2011) p53 inhibits mRNA 3′ processing through its interaction with the CstF/BARD1 complex. Oncogene 30:27, pages 3073-3083.
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Huijue Jia, Xuying Wang, Fei Liu, Ulf-Peter Guenther, Sukanya Srinivasan, James T. Anderson & Eckhard Jankowsky. (2011) The RNA Helicase Mtr4p Modulates Polyadenylation in the TRAMP Complex. Cell 145:6, pages 890-901.
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Murat A Cevher, Xiaokan Zhang, Sully Fernandez, Sergey Kim, Jorge Baquero, Per Nilsson, Sean Lee, Anders Virtanen & Frida E Kleiman. (2010) Nuclear deadenylation/polyadenylation factors regulate 3′ processing in response to DNA damage. The EMBO Journal 29:10, pages 1674-1687.
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Karen C. M. Moraes. (2009) RNA Surveillance: Molecular Approaches in Transcript Quality Control and their Implications in Clinical Diseases. Molecular Medicine 16:1-2, pages 53-68.
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Rachel Jones, Meredith B. Baker, Martina Weber, David G. Harrison, Gang Bao & Charles D. Searles. (2009) Molecular beacons can assess changes in expression and 3′-polyadenylation of human eNOS mRNA. American Journal of Physiology-Cell Physiology 296:3, pages C498-C504.
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Hellinida Thomadaki, Chris Milto Tsiapalis & Andreas Scorilas. (2007) The effect of the polyadenylation inhibitor cordycepin on human Molt-4 and Daudi leukaemia and lymphoma cell lines. Cancer Chemotherapy and Pharmacology 61:4, pages 703-711.
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Vasupradha Vethantham, Nishta Rao & James L. Manley. (2008) Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function. Genes & Development 22:4, pages 499-511.
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Sven Danckwardt, Matthias W Hentze & Andreas E Kulozik. (2008) 3′ end mRNA processing: molecular mechanisms and implications for health and disease. The EMBO Journal 27:3, pages 482-498.
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Hellinida Thomadaki, Andreas Scorilas, Chris Milto Tsiapalis & Maria Havredaki. (2007) The role of cordycepin in cancer treatment via induction or inhibition of apoptosis: implication of polyadenylation in a cell type specific manner. Cancer Chemotherapy and Pharmacology 61:2, pages 251-265.
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Hedda A. Meijer, Martin Bushell, Kirsti Hill, Timothy W. Gant, Anne E. Willis, Peter Jones & Cornelia H. de Moor. (2007) A novel method for poly(A) fractionation reveals a large population of mRNAs with a short poly(A) tail in mammalian cells. Nucleic Acids Research 35:19, pages e132.
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Hellinida Thomadaki, Maroulio Talieri & Andreas Scorilas. (2007) Prognostic value of the apoptosis related genes BCL2 and BCL2L12 in breast cancer. Cancer Letters 247:1, pages 48-55.
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Charles D. Searles. (2006) Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression. American Journal of Physiology-Cell Physiology 291:5, pages C803-C816.
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Martina WeberCurt H. HagedornDavid G. HarrisonCharles D. Searles. (2005) Laminar Shear Stress and 3′ Polyadenylation of eNOS mRNA. Circulation Research 96:11, pages 1161-1168.
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Frida E. Kleiman, Foon Wu-Baer, Danae Fonseca, Syuzo Kaneko, Richard Baer & James L. Manley. (2005) BRCA1/BARD1 inhibition of mRNA 3′ processing involves targeted degradation of RNA polymerase II. Genes & Development 19:10, pages 1227-1237.
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