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Research Article

Autoantibodies to intracellular autoantigens and their B-cell epitopes: Molecular Probes to Study the Autoimmune Response

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Pages 203-248 | Published online: 10 Oct 2008

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Eleni I. Kampylafka, Harry Alexopoulos, Avraam El Hamidieh, Marinos C. Dalakas, Evangelos Andreakos & Athanasios G. Tzioufas. (2015) Immunization of mice with a peptide derived from the HTLV-1 TAX1BP1 protein induces cross-reactive antibodies against aquaporin 4. Autoimmunity 48:7, pages 453-459.
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Song-Chou Hsieh & Chia-Li Yu. (2013) Autoantibody profiling in systemic lupus erythematosus. Current Biomarker Findings 3, pages 55-65.
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Ewa A. Szyszko, Kathrine Skarstein, Roland Jonsson & Karl A. Brokstad. (2011) Distinct phenotypes of plasma cells in spleen and bone marrow of autoimmune NOD.B10.H2b mice. Autoimmunity 44:5, pages 415-426.
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Thomas E Ichim, Xiufen Zheng, Motohiko Suzuki, Norihiko Kubo, Xusheng Zhang, Lisa R Min, Marianne E Beduhn, Neil H Riordan, Robert D Inman & Wei-Ping Min. (2008) Antigen-specific therapy of rheumatoid arthritis. Expert Opinion on Biological Therapy 8:2, pages 191-199.
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Sezer Okay. (2022) Involvement of retroelements in the autoimmune response in humans. Exploration of Medicine, pages 280-288.
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Matthew P. Baker, Timothy D. Jones & Paul Chamberlain. 2017. Protein Therapeutics. Protein Therapeutics 387 421 .
Jeremy Kiripolsky, Long Shen, Yichen Liang, Alisa Li, Lakshmanan Suresh, Yun Lian, Quan-Zhen Li, Daniel P. Gaile & Jill M. Kramer. (2017) Systemic manifestations of primary Sjögren's syndrome in the NOD.B10Sn-H2/J mouse model. Clinical Immunology 183, pages 225-232.
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Efstathia K. Kapsogeorgou & Athanasios G. Tzioufas. 2016. Connective Tissue Disease. Connective Tissue Disease 293 308 .
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N C Kyriakidis, E K Kapsogeorgou, V C Gourzi, O D Konsta, G E Baltatzis & A G Tzioufas. (2014) Toll-like receptor 3 stimulation promotes Ro52/TRIM21 synthesis and nuclear redistribution in salivary gland epithelial cells, partially via type I interferon pathway. Clinical and Experimental Immunology 178:3, pages 548-560.
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Nikolaos C. Kyriakidis, Efstathia K. Kapsogeorgou & Athanasios G. Tzioufas. (2014) A comprehensive review of autoantibodies in primary Sjögren's syndrome: Clinical phenotypes and regulatory mechanisms. Journal of Autoimmunity 51, pages 67-74.
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H. Alexopoulos, E.I. Kampylafka, I. Chatzi, M. Travasarou, K.E. Karageorgiou, M.C. Dalakas & A.G. Tzioufas. (2013) Reactivity to AQP4 epitopes in relapsing?remitting multiple sclerosis. Journal of Neuroimmunology 260:1-2, pages 117-120.
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Chiara Zingaretti, Milena Arigò, Angela Cardaci, Monica Moro, Mariacristina Crosti, Antonella Sinisi, Elisa Sugliano, Cristina Cheroni, Francesco Marabita, Renzo Nogarotto, Raoul Jean Pierre Bonnal, Paolo Marcatili, Maurizio Marconi, Annalinda Zignego, Paolo Muratori, Pietro Invernizzi, Piero Colombatto, Maurizia Brunetto, Ferruccio Bonino, Raffaele De Francesco, Jens Geginat, Massimiliano Pagani, Luigi Muratori, Sergio Abrignani & Mauro Bombaci. (2012) Identification of New Autoantigens by Protein Array Indicates a Role for IL4 Neutralization in Autoimmune Hepatitis. Molecular & Cellular Proteomics 11:12, pages 1885-1897.
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Athanasios G. Tzioufas, Ioanna P. Tatouli & Haralampos M. Moutsopoulos. (2012) Autoantibodies in Sjögren's syndrome: Clinical presentation and regulatory mechanisms. La Presse Médicale 41:9, pages e451-e460.
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Vito Racanelli, Marcella Prete, Gerta Musaraj, Franco Dammacco & Federico Perosa. (2011) Autoantibodies to intracellular antigens: Generation and pathogenetic role. Autoimmunity Reviews 10:8, pages 503-508.
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E.I. Kampylafka, J.G. Routsias, H. Alexopoulos, M.C. Dalakas, H.M. Moutsopoulos & A.G. Tzioufas. (2011) Fine specificity of antibodies against AQP4: Epitope mapping reveals intracellular epitopes. Journal of Autoimmunity 36:3-4, pages 221-227.
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Sandy Azzi, Vincent Parissi, Richard G. Maroun, Pierre Eid, Olivier Mauffret & Serge Fermandjian. (2010) The HIV-1 Integrase ?4-Helix Involved in LTR-DNA Recognition Is also a Highly Antigenic Peptide Element. PLoS ONE 5:12, pages e16001.
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John G. Routsias & Athanasios G. Tzioufas. (2010) Autoimmune response and target autoantigens in Sjogren’s syndrome. European Journal of Clinical Investigation 40:11, pages 1026-1036.
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John G. Routsias & Athanasios G. Tzioufas. (2010) B-cell epitopes of the intracellular autoantigens Ro/SSA and La/SSB: Tools to study the regulation of the autoimmune response. Journal of Autoimmunity 35:3, pages 256-264.
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Athanasios G. Tzioufas & John G. Routsias. (2010) Idiotype, anti-idiotype network of autoantibodies. Autoimmunity Reviews 9:9, pages 631-633.
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Markus H. Hoffmann, Sylvie Trembleau, Sylviane Muller & Günter Steiner. (2010) Nucleic acid-associated autoantigens: Pathogenic involvement and therapeutic potential. Journal of Autoimmunity 34:3, pages J178-J206.
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Christine J. Bryson, Tim D. Jones & Matthew P. Baker. (2010) Prediction of Immunogenicity of Therapeutic Proteins. BioDrugs 24:1, pages 1-8.
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John Routsias & Nikolaos Kyriakidis. (2010) . Molecular Medicine 16:1-2, pages 1.
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Michael Mahler & Marvin J. Fritzler. (2010) Epitope specificity and significance in systemic autoimmune diseases. Annals of the New York Academy of Sciences 1183:1, pages 267-287.
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Maite Duhalde-VegaJosé Luis AparicioLilia A. Retegui. (2009) Fine Specificity of Autoantibodies Induced By Mouse Hepatitis Virus A59. Viral Immunology 22:5, pages 287-294.
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Carlos J. Camacho, Yasuhiro Katsumata & Dana P. Ascherman. (2008) Structural and Thermodynamic Approach to Peptide Immunogenicity. PLoS Computational Biology 4:11, pages e1000231.
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David J. Blake, Scott A. Wetzel & Jean C. Pfau. (2008) Autoantibodies from mice exposed to Libby amphibole asbestos bind SSA/Ro52-enriched apoptotic blebs of murine macrophages. Toxicology 246:2-3, pages 172-179.
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Ioannis A. Tsonis, Stratis Avrameas & Haralampos M. Moutsopoulos. (2007) Autoimmunity and pathophysiology. Journal of Autoimmunity 29:4, pages 203-205.
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John G. Routsias & Athanasios G. Tzioufas. (2007) Sjögren’s Syndrome—Study of Autoantigens and Autoantibodies. Clinical Reviews in Allergy & Immunology 32:3, pages 238-251.
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Hasibe Artac, Hayrullah Alp, Sevgi Keles, Ismail Reisli & Recep Tunc. (2007) Systemic onset juvenile rheumatoid arthritis presenting with absence of B lymphocytes. Rheumatology International 27:10, pages 981-983.
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Melissa J. Bobeck, Joanne Cleary, Jenny A. Beckingham, P. Christine Ackroyd & Gary D. Glick. (2007) Effect of somatic mutation on DNA binding properties of anti-DNA autoantibodies. Biopolymers 85:5-6, pages 471-480.
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Eirik Bratland, Anette S. B?e Wolff, Jan Haavik, Olle K?mpe, Filip Sk?ldberg, Jaakko Perheentupa, Geir Bredholt, Per M. Knappskog & Eystein S. Husebye. (2007) Epitope mapping of human aromatic l-amino acid decarboxylase. Biochemical and Biophysical Research Communications 353:3, pages 692-698.
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X Li, V RiderB F Kimler & N I Abdou. (2016) Estrogen does not regulate CD154 mRNA stability in systemic lupus erythematosus T cells. Lupus 15:12, pages 852-857.
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E A Stea, J G Routsias, M Samiotaki, G Panayotou, E Papalambros, H M Moutsopoulos & A G Tzioufas. (2007) Analysis of parotid glands of primary Sjögren's syndrome patients using proteomic technology reveals altered autoantigen composition and novel antigenic targets. Clinical and Experimental Immunology 147:1, pages 81-89.
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