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Research Article

Do Lipid Lowering Drugs Reduce the Risk of Coronary Heart Disease?

Pages 603-621 | Published online: 29 Sep 2008

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Hong C Shen. (2009) Acyl hydroxypyrazoles as novel agonists for high-affinity nicotinic acid receptor GPR109A: WO2008051403. Expert Opinion on Therapeutic Patents 19:8, pages 1149-1155.
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Hong C Shen & Steven L Colletti. (2009) Novel patent publications on high-affinity nicotinic acid receptor agonists. Expert Opinion on Therapeutic Patents 19:7, pages 957-967.
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Giuseppe Lippi & Giancesare Guidi. (2003) Lipoprotein(a): An Emerging Cardiovascular Risk Factor. Critical Reviews in Clinical Laboratory Sciences 40:1, pages 1-42.
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Articles from other publishers (12)

Olga Bobileva, Rasma Bokaldere, Vija Gailite, Ilze Kaula, Martins Ikaunieks, Gunars Duburs, Ramona Petrovska, Ilona Mandrika, Janis Klovins & Einars Loza. (2014) Synthesis and evaluation of (E)-2-(acrylamido)cyclohex-1-enecarboxylic acid derivatives as HCA1, HCA2, and HCA3 receptor agonists. Bioorganic & Medicinal Chemistry 22:14, pages 3654-3669.
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Guo Li, Xiaoyan Deng, Chun Wu, Qi Zhou, Linjie Chen, Ying Shi, Haishan Huang & Naiming Zhou. (2011) Distinct Kinetic and Spatial Patterns of Protein Kinase C (PKC)- and Epidermal Growth Factor Receptor (EGFR)-dependent Activation of Extracellular Signal-regulated Kinases 1 and 2 by Human Nicotinic Acid Receptor GPR109A. Journal of Biological Chemistry 286:36, pages 31199-31212.
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Fa-Xiang Ding, Hong C. Shen, Larrisa C. Wilsie, Mihajlo L. Krsmanovic, Andrew K. Taggart, Ning Ren, Tian-Quan Cai, Junying Wang, Xinchun Tong, Tom G. Holt, Qing Chen, M. Gerard Waters, Milton L. Hammond, James R. Tata & Steven L. Colletti. (2010) Discovery of pyrazolyl propionyl cyclohexenamide derivatives as full agonists for the high affinity niacin receptor GPR109A. Bioorganic & Medicinal Chemistry Letters 20:11, pages 3372-3375.
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Hong C. Shen, Fa-Xiang Ding, Subharekha Raghavan, Qiaolin Deng, Silvi Luell, Michael J. Forrest, Ester Carballo-Jane, Larissa C. Wilsie, Mihajlo L. Krsmanovic, Andrew K. Taggart, Kenneth K. Wu, Tsuei-Ju Wu, Kang Cheng, Ning Ren, Tian-Quan Cai, Qing Chen, Junying Wang, Michael S. Wolff, Xinchun Tong, Tom G. Holt, M. Gerard Waters, Milton L. Hammond, James R. Tata & Steven L. Colletti. (2010) Discovery of a Biaryl Cyclohexene Carboxylic Acid (MK-6892): A Potent and Selective High Affinity Niacin Receptor Full Agonist with Reduced Flushing Profiles in Animals as a Preclinical Candidate. Journal of Medicinal Chemistry 53:6, pages 2666-2670.
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Hong C. Shen, Fa-Xiang Ding, Qiaolin Deng, Larissa C. Wilsie, Mihajlo L. Krsmanovic, Andrew K. Taggart, Ester Carballo-Jane, Ning Ren, Tian-Quan Cai, Tsuei-Ju Wu, Kenneth K. Wu, Kang Cheng, Qing Chen, Michael S. Wolff, Xinchun Tong, Tom G. Holt, M. Gerard Waters, Milton L. Hammond, James R. Tata & Steven L. Colletti. (2009) Discovery of Novel Tricyclic Full Agonists for the G-Protein-Coupled Niacin Receptor 109A with Minimized Flushing in Rats. Journal of Medicinal Chemistry 52:8, pages 2587-2602.
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Hong C. Shen, Andrew K.P. Taggart, Larissa C. Wilsie, M. Gerard Waters, Milton L. Hammond, James R. Tata & Steven L. Colletti. (2008) Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A. Bioorganic & Medicinal Chemistry Letters 18:18, pages 4948-4951.
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Hong C. Shen, Fa-Xiang Ding, Silvi Luell, Michael J. Forrest, Ester Carballo-Jane, Kenneth K. Wu, Tsuei-Ju Wu, Kang Cheng, Larissa C. Wilsie, Mihajlo L. Krsmanovic, Andrew K. Taggart, Ning Ren, Tian-Quan Cai, Qiaolin Deng, Qing Chen, Junying Wang, Michael S. Wolff, Xinchun Tong, Tom G. Holt, M. Gerard Waters, Milton L. Hammond, James R. Tata & Steven L. Colletti. (2007) Discovery of Biaryl Anthranilides as Full Agonists for the High Affinity Niacin Receptor. Journal of Medicinal Chemistry 50:25, pages 6303-6306.
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Hong C. Shen, Michael J. Szymonifka, Divya Kharbanda, Qiaolin Deng, Ester Carballo-Jane, Kenneth K. Wu, Tsuei-Ju Wu, Kang Cheng, Ning Ren, Tian-Quan Cai, Andrew K. Taggart, Junying Wang, Xinchun Tong, M. Gerard Waters, Milton L. Hammond, James R. Tata & Steven L. Colletti. (2007) Discovery of orally bioavailable and novel urea agonists of the high affinity niacin receptor GPR109A. Bioorganic & Medicinal Chemistry Letters 17:24, pages 6723-6728.
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Keyvan Mahboubi, Terri Witman-Jones, Jean E. Adamus, Jack T. Letsinger, Darren Whitehouse, Allan R. Moorman, Diane Sawicki, Nils Bergenhem & Stuart A. Ross. (2006) Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74. Biochemical and Biophysical Research Communications 340:2, pages 482-490.
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Dharam Agarwal & Helmut SeitzDavid Goldberg & George Soleas. 2001. Alcohol in Health and Disease. Alcohol in Health and Disease 547 572 .
Wei Wang, Alice Basinger, Richard A. Neese, Barry Shane, Su-A Myong, Mark Christiansen & Marc K. Hellerstein. (2001) Effect of nicotinic acid administration on hepatic very low density lipoprotein-triglyceride production. American Journal of Physiology-Endocrinology and Metabolism 280:3, pages E540-E547.
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M. Panteghini. (2001) Recent Advances in the Measurement of LDL Cholesterol in Serum. Neue Fortschritte bei der Messung von LDL Cholesterin in Serum. LaboratoriumsMedizin 25:7-8, pages 284-287.
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