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Research Article

Advances in the Signal Transduction of Ceramide and Related Sphingolipids

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Pages 511-573 | Published online: 29 Sep 2008

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Norman S. Radin. (2002) The Development of Aggressive Cancer: A Possible Role for Sphingolipids. Cancer Investigation 20:5-6, pages 779-786.
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Dayong Wu & Simin Nikbin Meydani. (2008) Age-associated changes in immune and inflammatory responses: impact of vitamin E intervention. Journal of Leukocyte Biology 84:4, pages 900-914.
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D. Thusitha U. Abeytunga, Lynne Oland, Arpad Somogyi & Robin Polt. (2008) Structural studies on the neutral glycosphingolipids of Manduca sexta. Bioorganic Chemistry 36:2, pages 70-76.
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Caroline Fasano, Jean-Pierre Niel, François Tercé & Jean-Pierre Miolan. (2007) Conduction nerveuse d’excitation sans potentiel d’action. médecine/sciences 23:12, pages 1075-1077.
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Caroline Fasano, François Tercé, Jean-Pierre Niel, Hang Thi Thu Nguyen, Abel Hiol, Justine Bertrand-Michel, Nicole Mallet, Xavier Collet & Jean-Pierre Miolan. (2007) Neuronal Conduction of Excitation without Action Potentials Based on Ceramide Production. PLoS ONE 2:7, pages e612.
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Koka Jayasimhulu, Shannon M. Hunt, Edna S. Kaneshiro, Yoko Watanabe & José-Luis Giner. (2007) Detection and identification of Bacteriovorax stolpii UKi2 sphingophosphonolipid molecular species. Journal of the American Society for Mass Spectrometry 18:3, pages 394-403.
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Jan Velíšek & Karel Cejpek. (2006) Biosynthesis of food constituents: Lipids. 2. Triacylglycerols, glycerophospholipids, and glyceroglycolipids - a review. Czech Journal of Food Sciences 24:6, pages 241-254.
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Caroline Fasano, Abel Hiol, Jean-Pierre Miolan & Jean-Pierre Niel. (2006) Les sphingolipides : vecteurs d’agents pathogènes et cause de maladies génétiques. médecine/sciences 22:4, pages 411-415.
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Veit Wascholowski & Athanassios Giannis. (2006) Sphingolactones: Selective and Irreversible Inhibitors of Neutral Sphingomyelinase. Angewandte Chemie International Edition 45:5, pages 827-830.
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Veit Wascholowski & Athanassios Giannis. (2006) Sphingolactone: selektive und irreversibel wirkende Inhibitoren der neutralen Sphingomyelinase. Angewandte Chemie 118:5, pages 841-845.
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Walid Elyassaki & Shiyong Wu. (2006) Lipid Rafts Mediate Ultraviolet Light–induced Fas Aggregation in M624 Melanoma Cells. Photochemistry and Photobiology 82:3, pages 787.
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Loukas G. Astrakas, Igor Goljer, Shingo Yasuhara, Katie E. Padfield, Qunhao Zhang, Suresh Gopalan, Michael N. Mindrinos, George Dai, Yong‐Ming Yu, J. A. Jeevendra Martyn, Ronald G. Tompkins, Laurence G. Rahme & A. Aria Tzika. (2005) Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma‐induced apoptosis. The FASEB Journal 19:11, pages 1431-1440.
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Anthony Falluel-Morel, Nicolas Aubert, David Vaudry, Magali Basille, Marc Fontaine, Alain Fournier, Hubert Vaudry & Bruno J. Gonzalez. (2004) Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells. Journal of Neurochemistry 91:5, pages 1231-1243.
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Yasushi Ito, Shinji Sato, Takamasa Ohashi, Shinsuke Nakayama, Kaoru Shimokata & Hiroaki Kume. (2004) Reduction of airway anion secretion via CFTR in sphingomyelin pathway. Biochemical and Biophysical Research Communications 324:2, pages 901-908.
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Yong J Lee & Andrew A Amoscato. 2004. TRAIL (TNF-Related Apoptosis-Inducing Ligand). TRAIL (TNF-Related Apoptosis-Inducing Ligand) 229 255 .
David P Relling, Kadon K Hintz & Jun Ren. (2003) Acute exposure of ceramide enhances cardiac contractile function in isolated ventricular myocytes. British Journal of Pharmacology 140:7, pages 1163-1168.
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Diana Escalante-Alcalde, Lidia Hernandez, Hervé Le Stunff, Ryu Maeda, Hyun-Shik Lee, Gang ChengJrJr, Vicki A. Sciorra, Ira Daar, Sarah Spiegel, Andrew J. Morris & Colin L. Stewart. (2003) The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning. Development 130:19, pages 4623-4637.
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Willem F Nieuwenhuizen, Sander van Leeuwen, Ralph W Jack, Maarten R Egmond & Friedrich Götz. (2003) Molecular cloning and characterization of the alkaline ceramidase from Pseudomonas aeruginosa PA01. Protein Expression and Purification 30:1, pages 94-104.
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Mitra Mahmoudi, Desley Willgoss, Leila Cuttle, Tao Yang, Betty Pat, Clay Winterford, Zoltan Endre, David W Johnson & Glenda C Gobé. (2003) In vivo and in vitro models demonstrate a role for caveolin‐1 in the pathogenesis of ischaemic acute renal failure . The Journal of Pathology 200:3, pages 396-405.
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H-H Chen, S Zhao & J-G Song. (2003) TGF-β1 suppresses apoptosis via differential regulation of MAP kinases and ceramide production. Cell Death & Differentiation 10:5, pages 516-527.
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Norman S. Radin. (2003) Designing anticancer drugs via the achilles heel: ceramide, allylic ketones, and mitochondria. Bioorganic & Medicinal Chemistry 11:10, pages 2123-2142.
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Stella Ibata-Ombetta, Thierry Idziorek, Pierre-André Trinel, Daniel Poulain & Thierry Jouault. (2003) Candida albicans Phospholipomannan Promotes Survival of Phagocytosed Yeasts through Modulation of Bad Phosphorylation and Macrophage Apoptosis. Journal of Biological Chemistry 278:15, pages 13086-13093.
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Amy L. CavalliNicole W. O'BrienSteven B. BarlowRomeo Betto, Christopher C. GlembotskiPhilip T. Palade & Roger A. Sabbadini. (2003) Expression and functional characterization of SCaMPER: a sphingolipid-modulated calcium channel of cardiomyocytes. American Journal of Physiology-Cell Physiology 284:3, pages C780-C790.
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Gele Liu, Mohammad H. Ghahremani, Behzad Banihashemi & Paul R. Albert. (2003) Diacylglycerol and ceramide formation induced by dopamine D2S receptors via Gβγ-subunits in Balb/c-3T3 cells. American Journal of Physiology-Cell Physiology 284:3, pages C640-C648.
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Madoka Sato, Margaret Markiewicz, Masoyoshi Yamanaka, Alicja Bielawska, Cungui Mao, Lina M. Obeid, Yusuf A. Hannun & Maria Trojanowska. (2003) Modulation of Transforming Growth Factor-β (TGF-β) Signaling by Endogenous Sphingolipid Mediators. Journal of Biological Chemistry 278:11, pages 9276-9282.
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C Fasano, J.P Miolan & J.P Niel. (2003) Modulation by C2 ceramide of the nicotinic transmission within the coeliac ganglion in the rabbit. Neuroscience 116:3, pages 753-759.
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Eduardo Latorre, M. Pilar Collado, Inmaculada Fernández, M. Dolores Aragonés & R. Edgardo Catalán. (2002) Signaling events mediating activation of brain ethanolamine plasmalogen hydrolysis by ceramide. European Journal of Biochemistry 270:1, pages 36-46.
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Gele Liu, Liliane Robillard, Behzad Banihashemi & Paul R. Albert. (2002) Growth Hormone-induced Diacylglycerol and Ceramide Formation via Gαi3 and Gβγ in GH4 Pituitary Cells. Journal of Biological Chemistry 277:50, pages 48427-48433.
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Huige LiPeter JunkAndrea HuwilerChristian BurkhardtThomas WallerathJosef PfeilschifterUlrich Förstermann. (2002) Dual Effect of Ceramide on Human Endothelial Cells. Circulation 106:17, pages 2250-2256.
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Sheng Zhao, Xiao-Yan Du, Jun-Song Chen, Yuan-Cong Zhou & Jian-Guo Song. (2002) Secretory Phospholipase A2 Inhibits Epidermal Growth Factor-Induced Receptor Activation. Experimental Cell Research 279:2, pages 354-364.
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Rebeca López-Marure, Gisela Gutiérrez, Criselda Mendoza, José Luis Ventura, Luis Sánchez, Elba Reyes Maldonado, Alejandro Zentella & Luis Felipe Montaño. (2002) Ceramide promotes the death of human cervical tumor cells in the absence of biochemical and morphological markers of apoptosis. Biochemical and Biophysical Research Communications 293:3, pages 1028-1036.
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Sheng Zhao, Xiao-Yan Du, Min-Qiang Chai, Jun-Song Chen, Yuan-Chong Zhou & Jian-Guo Song. (2002) Secretory phospholipase A2 induces apoptosis via a mechanism involving ceramide generation. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1581:3, pages 75-88.
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Kenneth A. Voss, Paul C. Howard, Ronald T. Riley, Raghubir P. Sharma, Thomas J. Bucci & Ronald J. Lorentzen. (2002) Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (=F. verticillioides). Cancer Detection and Prevention 26:1, pages 1-9.
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Willem F Nieuwenhuizen, Sander van Leeuwen, Friedrich Götz & Maarten R Egmond. (2002) Synthesis of a novel fluorescent ceramide analogue and its use in the characterization of recombinant ceramidase from Pseudomonas aeruginosa PA01. Chemistry and Physics of Lipids 114:2, pages 181-191.
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Toshiaki Suzuki, Hiroshi Sugiya & Shunsuke Furuyama. (2002) Sphingosine Inhibits GTP?S-stimulated Inositol Trisphosphate Formation in Rat Parotid Acinar Cells. International Journal of Oral-Medical Sciences 1:1, pages 23-28.
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Leonard Kleine, Gele Liu, Normand Leblanc & Richard L. Hébert. (2002) Bradykinin stimulates ceramide production by activating specific BK-B 1 receptor in rat small artery . American Journal of Physiology-Heart and Circulatory Physiology 282:1, pages H175-H183.
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Eric Solary, Nathalie Droin, Olivier Sordet, Cédric Rebe, Rodolphe Filomenko, Anne Wotawa, Stephanie Plenchette & Patrick Ducoroy. 2002. Anticancer Drug Development. Anticancer Drug Development 55 76 .
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Tatsuya Kanto, Pawel Kalinski, Oriana C. Hunter, Michael T. Lotze & Andrew A. Amoscato. (2001) Ceramide Mediates Tumor-Induced Dendritic Cell Apoptosis. The Journal of Immunology 167:7, pages 3773-3784.
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Lars I. Hellgren. (2001) Occurrence of bioactive sphingolipids in meat and fish products. European Journal of Lipid Science and Technology 103:10, pages 661-667.
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Justyna Sarna, Silvia R. P. Miranda, Edward H. Schuchman & Richard Hawkes. (2001) Patterned cerebellar Purkinje cell death in a transgenic mouse model of Niemann Pick type A/B disease. European Journal of Neuroscience 13:10, pages 1873-1880.
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Yoko Watanabe, Masaharu Nakajima, Tsutomu Hoshino, Koda Jayasimhulu, Elwood E. Brooks & Edna S. Kaneshiro. (2001) A novel sphingophosphonolipid head group 1-hydroxy-2-aminoethyl phosphonate in Bdellovibrio stolpii. Lipids 36:5, pages 513-519.
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Ingar Olsen & Erik Jantzen. (2001) Sphingolipids in Bacteria and Fungi. Anaerobe 7:2, pages 103-112.
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Madalina Condrescu & John P. Reeves. (2001) Inhibition of Sodium-Calcium Exchange by Ceramide and Sphingosine. Journal of Biological Chemistry 276:6, pages 4046-4054.
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Norman S. Radin. (2001) Killing cancer cells by poly-drug elevation of ceramide levels. European Journal of Biochemistry 268:2, pages 193-204.
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A. Muralikrishna Rao, J. F. Hatcher & R. J. Dempsey. (2008) Lipid Alterations in Transient Forebrain Ischemia. Journal of Neurochemistry 75:6, pages 2528-2535.
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Robert Bittman & Christopher A. Verbicky. (2000) Methanolysis of sphingomyelin: toward an epimerization-free methodology for the preparation of d-erythro-sphingosylphosphocholine. Journal of Lipid Research 41:12, pages 2089-2093.
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