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Original Articles

The Key Events Dose-Response Framework: A Foundation for Examining Variability in Elicitation Thresholds for Food Allergens

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Pages 729-739 | Published online: 11 Sep 2009

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Binaka Prabashini Dasanayaka, Zhenxing Li, Siddanakoppalu Narayana Pramod, Yan Chen, Mati Ullah Khan & Hong Lin. (2022) A review on food processing and preparation methods for altering fish allergenicity. Critical Reviews in Food Science and Nutrition 62:7, pages 1951-1970.
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Ted W. Simon, S. Stoney Simons$suffix/text()$suffix/text(), R. Julian Preston, Alan R. Boobis, Samuel M. Cohen, Nancy G. Doerrer, Penelope A. Fenner-Crisp, Tami S. McMullin, Charlene A. McQueen & J. Craig Rowlands. (2014) The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events. Critical Reviews in Toxicology 44:sup3, pages 17-43.
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Luke Johnson, MyronL. Smith, Melissa Begin, Bruce Fraser & J. David Miller. (2010) Remediating Office Environments of Spore-Forming Bacteria. Journal of Occupational and Environmental Hygiene 7:10, pages 585-592.
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Elizabeth Julien , AlanR. Boobis, StephenS. Olin & The ILSI Research Foundation Threshold Working Group. (2009) The Key Events Dose-Response Framework: A Cross-Disciplinary Mode-of-Action Based Approach to Examining Dose-Response and Thresholds. Critical Reviews in Food Science and Nutrition 49:8, pages 682-689.
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Articles from other publishers (17)

E. V. Kryuchenko, Yu. A. Kuzlyakina, I. M. Chernukha & V. S. Zamula. (2022) Food allergens: threshold levels and methodologies for risk management. Food systems 4:4, pages 246-254.
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Olaya Amor-Gutiérrez, Giulia Selvolini, M. Teresa Fernández-Abedul, Alfredo de la Escosura-Muñiz & Giovanna Marrazza. (2020) Folding-Based Electrochemical Aptasensor for the Determination of β-Lactoglobulin on Poly-L-Lysine Modified Graphite Electrodes. Sensors 20:8, pages 2349.
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Rod A. Herman & Gregory S. Ladics. (2018) Allergenic sensitization versus elicitation risk criteria for novel food proteins. Regulatory Toxicology and Pharmacology 94, pages 283-285.
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Jon Ashley, Yunus Shukor, Roberta D’Aurelio, Linda Trinh, Thomas L. Rodgers, Jeff Temblay, Mike Pleasants & Ibtisam E. Tothill. (2018) Synthesis of Molecularly Imprinted Polymer Nanoparticles for α-Casein Detection Using Surface Plasmon Resonance as a Milk Allergen Sensor. ACS Sensors 3:2, pages 418-424.
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R. Selb, J.M. Wal, F.J. Moreno, M. Lovik, C. Mills, K. Hoffmann-Sommergruber & A. Fernandez. (2017) Assessment of endogenous allergenicity of genetically modified plants exemplified by soybean – Where do we stand?. Food and Chemical Toxicology 101, pages 139-148.
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R.K. Ward. 2015. Handbook of Food Allergen Detection and Control. Handbook of Food Allergen Detection and Control 1 15 .
Kitti Török, Vanda Horváth, Ágnes Horváth, Lívia Hajas, Zsuzsanna Bugyi & Sándor Tömösközi. (2014) Investigation of incurred single- and multi-component model food matrices for determination of food proteins triggering allergy and coeliac disease. European Food Research and Technology 239:6, pages 923-932.
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. (2014) Scientific Opinion on the evaluation of allergenic foods and food ingredients for labelling purposes. EFSA Journal 12:11.
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Dean F. Bushey, Gary A. Bannon, Bryan F. Delaney, Gerson Graser, Mary Hefford, Xiaoxu Jiang, Thomas C. Lee, Krishna M. Madduri, Michael Pariza, Laura S. Privalle, Rakesh Ranjan, Gloria Saab-Rincon, Barry W. Schafer, Jay J. Thelen, John X.Q. Zhang & Marc S. Harper. (2014) Characteristics and safety assessment of intractable proteins in genetically modified crops. Regulatory Toxicology and Pharmacology 69:2, pages 154-170.
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Annette Kuehn, Ines Swoboda, Karthik Arumugam, Christiane Hilger & François Hentges. (2014) Fish Allergens at a Glance: Variable Allergenicity of Parvalbumins, the Major Fish Allergens. Frontiers in Immunology 5.
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Sue Hattersley & Rachel Ward. 2014. Risk Management for Food Allergy. Risk Management for Food Allergy 273 289 .
A. Fernandez, E.N.C. Mills, M. Lovik, A. Spoek, A. Germini, A. Mikalsen & J.M. Wal. (2013) Endogenous allergens and compositional analysis in the allergenicity assessment of genetically modified plants. Food and Chemical Toxicology 62, pages 1-6.
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Linda Monaci, Ilario Losito, Elisabetta De Angelis, Rosa Pilolli & Angelo Visconti. (2013) Multi-allergen quantification of fining-related egg and milk proteins in white wines by high-resolution mass spectrometry. Rapid Communications in Mass Spectrometry 27:17, pages 2009-2018.
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John Bukowski, Mark Nicolich & R. Jeffrey Lewis. (2012) Extreme Sensitivity and the Practical Implications of Risk Assessment Thresholds. Dose-Response 11:2, pages dose-response.1.
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S.H. Magnússon, H. Gunnlaugsdóttir, H. van Loveren, F. Holm, N. Kalogeras, O. Leino, J.M. Luteijn, G. Odekerken, M.V. Pohjola, M.J. Tijhuis, J.T. Tuomisto, Ø. Ueland, B.C. White & H. Verhagen. (2012) State of the art in benefit–risk analysis: Food microbiology. Food and Chemical Toxicology 50:1, pages 33-39.
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. (2011) Report on Stakeholders' activities in the area of emerging risks. EFSA Supporting Publications 8:6.
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Mareike Richter, Sigrid Haas-Lauterbach & Karl Schmitt. (2010) Rapid lateral flow tests in a Hazard Analysis of Critical Control Points-based approach for allergen monitoring. Quality Assurance and Safety of Crops & Foods 2:4, pages 165-172.
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