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Original Articles

Recent Research in Antihypertensive Activity of Food Protein-derived Hydrolyzates and Peptides

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Dinesh Kumar Chellappan, Jestin Chellian, Nur Suraiza Nabila Rahmah, Wee Jin Gan, Priyanka Banerjee, Saptarshi Sanyal, Pradipta Banerjee, Nandini Ghosh, Tanner Guith, Amitava Das, Gaurav Gupta, Sachin Kumar Singh, Kamal Dua, Anil Philip Kunnath, Nur Azeyanti Norhashim, Kuan Hung Ong & Kishneth Palaniveloo. (2023) Hypoglycaemic Molecules for the Management of Diabetes Mellitus from Marine Sources. Diabetes, Metabolic Syndrome and Obesity 16, pages 2187-2223.
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Na Wang, Xiaotong Cui, Yumin Duan, Shu Yang, Peng Wang, Ahmed S. M. Saleh & Zhigang Xiao. (2023) Potential health benefits and food applications of rice bran protein: research advances and challenges. Food Reviews International 39:6, pages 3578-3601.
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Qin Wu, Zhijian Guo, Zerong Zhou, Mengyuan Jin, Qizhang Li & Xuanwei Zhou. (2022) Recent advances in bioactive peptides from cereal-derived Foodstuffs. International Journal of Food Sciences and Nutrition 73:7, pages 875-888.
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Xuxiao Gong, Qi An, Liqing Le, Fang Geng, Liangzhen Jiang, Jun Yan, Dabing Xiang, Lianxin Peng, Liang Zou, Gang Zhao & Yan Wan. (2022) Prospects of cereal protein-derived bioactive peptides: Sources, bioactivities diversity, and production. Critical Reviews in Food Science and Nutrition 62:11, pages 2855-2871.
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Betul Kisioglu & Reyhan Nergiz-Unal. (2018) The powerful story against cardiovascular diseases: Dietary factors. Food Reviews International 34:8, pages 713-745.
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Ya-Fei Liu, Indrawati Oey, Phil Bremer, Alan Carne & Pat Silcock. (2018) Bioactive peptides derived from egg proteins: A review. Critical Reviews in Food Science and Nutrition 58:15, pages 2508-2530.
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Articles from other publishers (40)

Tapas Roy, Anupama Singh, T.P. Sari & Snigdha Homroy. (2023) Rice protein: Emerging insights of extraction, structural characteristics, functionality, and application in the food industry. Journal of Food Composition and Analysis 123, pages 105581.
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Qi Liu, Shan Shao, Jingyu Bao, Syed Jalil Shah, Shumin Yue, Xinqi Luan, Qing Liu, Linguang Xing, Zhongfeng Shi, Zhenxia Zhao & Zhongxing Zhao. (2023) High accuracy prediction of dipeptide angiotensin-converting enzyme (ACE) inhibitory activity by improving the credibility of the 3D-quantitative structure-activity relationship (3D-QSAR) model database and investigating inhibition mechanism. Process Biochemistry 131, pages 114-124.
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Andreza Pereira de Amorim, Yanara Alessandra Santana Moura, Karoline Mirella Soares de Souza, Ana Lúcia Figueiredo Porto & Raquel Pedrosa Bezerra. (2023) Encapsulation of peptides inhibitors of the angiotensin-converting enzyme: A systematic review. Materials Today Communications 36, pages 106850.
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Kevin M. R. Nijssen, Peter J. Joris, Ronald P. Mensink & Jogchum Plat. (2023) Longer-term effects of the egg-protein hydrolysate NWT-03 on arterial stiffness and cardiometabolic risk markers in adults with metabolic syndrome: a randomized, double-blind, placebo-controlled, crossover trial. European Journal of Clinical Nutrition.
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Sonal Prasad & Tabish Qidwai. (2023) Angiotensin-Converting Enzyme Inhibition Properties and Antioxidant Effects of Plants and their Bioactive Compounds as Cardioprotective Agent. Letters in Drug Design & Discovery 20:4, pages 457-468.
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Qiaonan Zhu, Jiawen Xue, Peng Wang, Xianbo Wang, Jiaojiao Zhang, Xuezhi Fang, Zhiping He & Fenghua Wu. (2023) Identification of a Novel ACE Inhibitory Hexapeptide from Camellia Seed Cake and Evaluation of Its Stability. Foods 12:3, pages 501.
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Seto Windarto, Meng-Chou Lee, Happy Nursyam & Jue-Liang Hsu. (2022) First Report of Screening of Novel Angiotensin-I Converting Enzyme Inhibitory Peptides Derived from the Red Alga Acrochaetium sp.. Marine Biotechnology 24:5, pages 882-894.
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Songmin Cao, Zixu Wang, Lujuan Xing, Lei Zhou & Wangang Zhang. (2022) Bovine Bone Gelatin-Derived Peptides: Food Processing Characteristics and Evaluation of Antihypertensive and Antihyperlipidemic Activities. Journal of Agricultural and Food Chemistry 70:32, pages 9877-9887.
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Hao Yue, Yingying Tian, Xiaoxuan Feng, Yuying Bo, Zhibing Leng, Ping Dong, Changhu Xue & Jingfeng Wang. (2022) Novel peptides from sea cucumber intestinal hydrolysates promote longitudinal bone growth in adolescent mice through accelerating cell cycle progress by regulating glutamine metabolism. Food & Function 13:14, pages 7730-7739.
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Sugiyati Ningrum, Aji Sutrisno & Jue-Liang Hsu. (2022) An exploration of angiotensin-converting enzyme (ACE) inhibitory peptides derived from gastrointestinal protease hydrolysate of milk using a modified bioassay-guided fractionation approach coupled with in silico analysis. Journal of Dairy Science 105:3, pages 1913-1928.
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Congcong Li, Kaifeng Liu, Siao Chen, Lu Han & Weiwei Han. (2022) Gaussian Accelerated Molecular Dynamics Simulations Investigation on the Mechanism of Angiotensin-Converting Enzyme (ACE) C-Domain Inhibition by Dipeptides. Foods 11:3, pages 327.
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Chandana Sosalagere, Bababode Adesegun Kehinde & Poorva Sharma. (2022) Isolation and functionalities of bioactive peptides from fruits and vegetables: A reviews. Food Chemistry 366, pages 130494.
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Jing Wang, Guoliang Wang, Yufeng Zhang, Runguang Zhang & Youlin Zhang. (2021) Novel Angiotensin-Converting Enzyme Inhibitory Peptides Identified from Walnut Glutelin-1 Hydrolysates: Molecular Interaction, Stability, and Antihypertensive Effects. Nutrients 14:1, pages 151.
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Glenise B. Voss, Maria João P. Monteiro, Paula Jauregi, Luísa M.P. Valente & Manuela E. Pintado. (2021) Functional characterisation and sensory evaluation of a novel synbiotic okara beverage. Food Chemistry 340, pages 127793.
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Bhuvnesh Sareen & Amita Bhattacharya. 2021. Biotechnology of Anti-diabetic Medicinal Plants. Biotechnology of Anti-diabetic Medicinal Plants 65 88 .
Agustina E. Nardo, Santiago Suárez, Alejandra V. Quiroga & María Cristina Añón. (2020) Amaranth as a Source of Antihypertensive Peptides. Frontiers in Plant Science 11.
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Marta Miguel, Dalton V. Vassallo & Giulia A. Wiggers. (2020) Bioactive Peptides and Hydrolysates from Egg Proteins as a New Tool for Protection Against Cardiovascular Problems. Current Pharmaceutical Design 26:30, pages 3676-3683.
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Santiago Suárez, Paula Aphalo, Gustavo Rinaldi, Maria Cristina Añón & Alejandra Quiroga. (2020) Effect of amaranth proteins on the RAS system. In vitro, in vivo and ex vivo assays. Food Chemistry 308, pages 125601.
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Gongnian Xiao, Yuanzhe Chen, Ruosi Fang, Chaogeng Xiao, Haina Yuan, Bingquan Chu, Xuangan Liu & Jinyan Gong. (2019) Salt‐tolerant Staphylococcus bacteria induce structural and nutritional alterations of salted duck egg white . Food Science & Nutrition 7:12, pages 3941-3949.
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Seung Yun Lee & Sun Jin Hur. (2019) Purification of novel angiotensin converting enzyme inhibitory peptides from beef myofibrillar proteins and analysis of their effect in spontaneously hypertensive rat model. Biomedicine & Pharmacotherapy 116, pages 109046.
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Ya-Hui Shih, Fu-An Chen, Li-Fei Wang & Jue-Liang Hsu. (2019) Discovery and Study of Novel Antihypertensive Peptides Derived from Cassia obtusifolia Seeds . Journal of Agricultural and Food Chemistry 67:28, pages 7810-7820.
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Charlotte Grootaert, Stefan Voorspoels, Griet Jacobs, Bea Matthijs, Sam Possemiers, Hans Van der Saag, John Van Camp & Alice Lucey. (2019) Clinical aspects of egg bioactive peptide research: a review. International Journal of Food Science & Technology 54:6, pages 1967-1975.
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Guowei Shu, Xiaoyu Shi, He Chen, Zhe Ji & Jiangpeng Meng. (2018) Optimization of Nutrient Composition for Producing ACE Inhibitory Peptides from Goat Milk Fermented by Lactobacillus bulgaricus LB6. Probiotics and Antimicrobial Proteins 11:2, pages 723-729.
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Dianzhi Hou, Laraib Yousaf, Yong Xue, Jinrong Hu, Jihong Wu, Xiaosong Hu, Naihong Feng & Qun Shen. (2019) Mung Bean (Vigna radiata L.): Bioactive Polyphenols, Polysaccharides, Peptides, and Health Benefits. Nutrients 11:6, pages 1238.
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Xiongdiao Lan, Lixia Sun, Yaseen Muhammad, Zefen Wang, Haibo Liu, Jianhua Sun, Liqin Zhou, Xuezhen Feng, Dankui Liao & Shuangfei Wang. (2018) Studies on the Interaction between Angiotensin-Converting Enzyme (ACE) and ACE Inhibitory Peptide from Saurida elongata . Journal of Agricultural and Food Chemistry 66:51, pages 13414-13422.
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Shahira Ezzat, Mahitab Bishbishy, Solomon Habtemariam, Bahare Salehi, Mehdi Sharifi-Rad, Natália Martins & Javad Sharifi-Rad. (2018) Looking at Marine-Derived Bioactive Molecules as Upcoming Anti-Diabetic Agents: A Special Emphasis on PTP1B Inhibitors. Molecules 23:12, pages 3334.
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Cesarea Joel, Christoper Sutopo, Arief Prajitno, Jui-Hsin Su & Jue-Liang Hsu. (2018) Screening of Angiotensin-I Converting Enzyme Inhibitory Peptides Derived from Caulerpa lentillifera. Molecules 23:11, pages 3005.
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Chathuni Jayathilake, Rizliya Visvanathan, Afka Deen, Ruksheela Bangamuwage, Barana C Jayawardana, Srinivas Nammi & Ruvini Liyanage. (2018) Cowpea: an overview on its nutritional facts and health benefits. Journal of the Science of Food and Agriculture 98:13, pages 4793-4806.
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Yuki Taga, Osamu Hayashida, Ahmed Ashour, Yhiya Amen, Masashi Kusubata, Kiyoko Ogawa-Goto, Kuniyoshi Shimizu & Shunji Hattori. (2018) Characterization of Angiotensin-Converting Enzyme Inhibitory Activity of X-Hyp-Gly-Type Tripeptides: Importance of Collagen-Specific Prolyl Hydroxylation. Journal of Agricultural and Food Chemistry 66:33, pages 8737-8743.
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Qian Sun, Fusheng Chen, Fang Geng, Yongkang Luo, Siyi Gong & Zhengqiang Jiang. (2018) A novel aspartic protease from Rhizomucor miehei expressed in Pichia pastoris and its application on meat tenderization and preparation of turtle peptides. Food Chemistry 245, pages 570-577.
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Chao Zhao, Chengfeng Yang, Bin Liu, Luan Lin, Satyajit D. Sarker, Lutfun Nahar, Hua Yu, Hui Cao & Jianbo Xiao. (2018) Bioactive compounds from marine macroalgae and their hypoglycemic benefits. Trends in Food Science & Technology 72, pages 1-12.
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Marta Gallego, Leticia Mora & Fidel Toldrá. (2018) Health relevance of antihypertensive peptides in foods. Current Opinion in Food Science 19, pages 8-14.
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María J. Beriain, Inmaculada Gómez, Francisco C. Ibáñez, M. Victoria Sarriés & Ana I. Ordóñez. 2018. Food Quality: Balancing Health and Disease. Food Quality: Balancing Health and Disease 1 74 .
E.C.Y. Li-Chan & I.M.E. Lacroix. 2018. Proteins in Food Processing. Proteins in Food Processing 1 25 .
Mingrong Guo, Xujun Chen, Yanling Wu, Lujia Zhang, Weixue Huang, Ying Yuan, Ming Fang, Jingli Xie & Dongzhi Wei. (2017) Angiotensin I-converting enzyme inhibitory peptides from Sipuncula (Phascolosoma esculenta): Purification, identification, molecular docking and antihypertensive effects on spontaneously hypertensive rats. Process Biochemistry 63, pages 84-95.
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Shiqi Lin, Huanglei Pan, Hongli Wu, Difeng Ren & Jun Lu. (2017) Role of the ACE2-Ang-(1-7)-Mas axis in blood pressure regulation and its potential as an antihypertensive in functional foods. Molecular Medicine Reports 16:4, pages 4403-4412.
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Dwi Yuli Pujiastuti, Ya-Hui Shih, Wei-Lin Chen, Sukoso & Jue-Liang Hsu. (2017) Screening of angiotensin-I converting enzyme inhibitory peptides derived from soft-shelled turtle yolk using two orthogonal bioassay-guided fractionations. Journal of Functional Foods 28, pages 36-47.
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Ida-Johanne Jensen & Hanne Mæhre. (2016) Preclinical and Clinical Studies on Antioxidative, Antihypertensive and Cardioprotective Effect of Marine Proteins and Peptides—A Review. Marine Drugs 14:11, pages 211.
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Huanglei Pan, Xingxing She, Hongli Wu, Jun Ma, Difeng Ren & Jun Lu. (2015) Long-Term Regulation of the Local Renin–Angiotensin System in the Myocardium of Spontaneously Hypertensive Rats by Feeding Bioactive Peptides Derived from Spirulina platensis . Journal of Agricultural and Food Chemistry 63:35, pages 7765-7774.
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Orachorn Boonla, Upa Kukongviriyapan, Poungrat Pakdeechote, Veerapol Kukongviriyapan, Patchareewan Pannangpetch & Supawan Thawornchinsombut. (2015) Peptides-Derived from Thai Rice Bran Improves Endothelial Function in 2K-1C Renovascular Hypertensive Rats. Nutrients 7:7, pages 5783-5799.
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