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Article

Gut microbiota-bone axis

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Pages 1664-1672 | Received 28 Nov 2014, Accepted 16 Jan 2015, Published online: 01 Mar 2017

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Xiao Chen, Zheng Zhang, Yan Hu, Jin Cui, Xin Zhi, Xiaoqun Li, Hao Jiang, Yao Wang, Zhengrong Gu, Zili Qiu, Xin Dong, Yuhong Li & Jiacan Su. (2020) Lactulose Suppresses Osteoclastogenesis and Ameliorates Estrogen Deficiency-Induced Bone Loss in Mice. Aging and disease 11:3, pages 629.
Crossref
Yara Loyanne de Almeida Silva Levi, Raquel Narciso Picchi, Evelyn Kellyn Trindade Silva, Hermann Bremer Neto, Rosana Leal do Prado, Adrieli de Paula Neves, Michel Reis Messora & Luciana Prado Maia. (2019) Probiotic Administration Increases Mandibular Bone Mineral Density on Rats Exposed to Cigarette Smoke Inhalation. Brazilian Dental Journal 30:6, pages 634-640.
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Na Wang, Rui Li, Haijiang Lin, Chaowei Fu, Xuecai Wang, Yiming Zhang, Meifang Su, Peixin Huang, Junhua Qian, Feng Jiang, Hexing Wang, Lufang Jiang, Xin Yu, Jianxiang Liu, Yue Chen & Qingwu Jiang. (2019) Enriched taxa were found among the gut microbiota of centenarians in East China. PLOS ONE 14:10, pages e0222763.
Crossref
Aaron Lerner & Torsten Matthias. 2019. Mosaic of Autoimmunity. Mosaic of Autoimmunity 315 321 .
Florian Kuehn, Fatemeh Adiliaghdam, Sulaiman R. Hamarneh, Robin Vasan, Enyu Liu, Yang Liu, Juan M. Ramirez, Raza S. Hoda, Alexander R. Munoz, Frank C. Ko, Michael Armanini, Daniel J. Brooks, Mary L. Bouxsein, Marie B. Demay & Richard A. Hodin. (2018) Loss of Intestinal Alkaline Phosphatase Leads to Distinct Chronic Changes in Bone Phenotype. Journal of Surgical Research 232, pages 325-331.
Crossref
C R Villa, A Taibi, J Chen, W E Ward & E M Comelli. (2017) Colonic Bacteroides are positively associated with trabecular bone structure and programmed by maternal vitamin D in male but not female offspring in an obesogenic environment. International Journal of Obesity 42:4, pages 696-703.
Crossref
Corrie M. Whisner & Luisa F. Castillo. (2017) Prebiotics, Bone and Mineral Metabolism. Calcified Tissue International 102:4, pages 443-479.
Crossref
Qingqing Feng, Wei-Dong Chen & Yan-Dong Wang. (2018) Gut Microbiota: An Integral Moderator in Health and Disease. Frontiers in Microbiology 9.
Crossref
Elena Biagi, Simone Rampelli, Silvia Turroni, Sara Quercia, Marco Candela & Patrizia Brigidi. (2017) The gut microbiota of centenarians: Signatures of longevity in the gut microbiota profile. Mechanisms of Ageing and Development 165, pages 180-184.
Crossref
Naiomy Deliz Rios-Arce, Fraser L. Collins, Jonathan D. Schepper, Michael D. Steury, Sandi Raehtz, Heather Mallin, Danny T. Schoenherr, Narayanan Parameswaran & Laura R. McCabe. 2017. Understanding the Gut-Bone Signaling Axis. Understanding the Gut-Bone Signaling Axis 151 183 .
Christopher Villa, Jianmin Chen, Bijun Wen, Sandra Sacco, Amel Taibi, Wendy Ward & Elena Comelli. (2016) Maternal Dietary Vitamin D Does Not Program Systemic Inflammation and Bone Health in Adult Female Mice Fed an Obesogenic Diet. Nutrients 8:11, pages 675.
Crossref

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