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Article

L-theanine, unique amino acid of tea, and its metabolism, health effects, and safety

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Pages 1681-1687 | Received 28 Jan 2015, Accepted 03 Feb 2015, Published online: 01 Mar 2017

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Crossref
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Crossref
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Hidese, Ogawa, Ota, Ishida, Yasukawa, Ozeki & Kunugi. (2019) Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients 11:10, pages 2362.
Crossref
Anca Zanfirescu, Anca Ungurianu, Aristides M. Tsatsakis, George M. Nițulescu, Demetrios Kouretas, Aris Veskoukis, Dimitrios Tsoukalas, Ayse B. Engin, Michael Aschner & Denisa Margină. (2019) A Review of the Alleged Health Hazards of Monosodium Glutamate. Comprehensive Reviews in Food Science and Food Safety 18:4, pages 1111-1134.
Crossref
Jianan Zhang, Dongxiao Sun-Waterhouse, Guowan Su & Mouming Zhao. (2019) New insight into umami receptor, umami/umami-enhancing peptides and their derivatives: A review. Trends in Food Science & Technology 88, pages 429-438.
Crossref
Yafang Wang, Yanqiu Zuo, Siyu Deng, Feng Zhu, Qin Liu, Ruru Wang, Tao Li, Huimei Cai, Xiaochun Wan, Zijian Xie, Zhongwen Xie & Daxiang Li. (2019) Using Caffeine and Free Amino Acids To Enhance the Transepithelial Transport of Catechins in Caco-2 Cells. Journal of Agricultural and Food Chemistry 67:19, pages 5477-5485.
Crossref
Keiko Unno & Yoriyuki Nakamura. 2019. Caffeinated and Cocoa Based Beverages. Caffeinated and Cocoa Based Beverages 209 234 .
Yahya Altınkaynak, Birgül Kural, Buket A. Akcan, Akın Bodur, Serap Özer, Esin Yuluğ, Sevdegül Munğan, Cansu Kaya & Asım Örem. (2018) Protective effects of L-theanine against doxorubicin-induced nephrotoxicity in rats. Biomedicine & Pharmacotherapy 108, pages 1524-1534.
Crossref
Jessica Fiori, Benedetta Pasquini, Claudia Caprini, Serena Orlandini, Sandra Furlanetto & Roberto Gotti. (2018) Chiral analysis of theanine and catechin in characterization of green tea by cyclodextrin-modified micellar electrokinetic chromatography and high performance liquid chromatography. Journal of Chromatography A 1562, pages 115-122.
Crossref
Dongxu Wang, Min Cai, Taotao Wang, Guangshan Zhao, Jinbao Huang, Haisong Wang, Frank Qian, Chi-Tang Ho & Yijun Wang. (2018) Theanine supplementation prevents liver injury and heat shock response by normalizing hypothalamic-pituitaryadrenal axis hyperactivity in mice subjected to whole body heat stress. Journal of Functional Foods 45, pages 181-189.
Crossref
Arrigo F.G. Cicero, Federica Fogacci & Maciej Banach. (2018) Botanicals and phytochemicals active on cognitive decline: The clinical evidence. Pharmacological Research 130, pages 204-212.
Crossref
Wei-Jie Zeng, Zhi Tan, Xing-Fei Lai, Ya-Nan Xu, Chun-Lin Mai, Jun Zhang, Zhen-Jia Lin, Xian-Guo Liu, Shi-Li Sun & Li-Jun Zhou. (2018) Topical delivery of l -theanine ameliorates TPA-induced acute skin inflammation via downregulating endothelial PECAM-1 and neutrophil infiltration and activation. Chemico-Biological Interactions 284, pages 69-79.
Crossref
Shu-Qing Chen, Ze-Shi Wang, Yi-Xiao Ma, Wei Zhang, Jian-Liang Lu, Yue-Rong Liang & Xin-Qiang Zheng. (2018) Neuroprotective Effects and Mechanisms of Tea Bioactive Components in Neurodegenerative Diseases. Molecules 23:3, pages 512.
Crossref
A. B. Katasonov. (2018) Neurobiological effects of theanine and its possible use in neurology and psychiatry. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 118:11, pages 118.
Crossref
Xinyuan Hao, Lu Wang, Jianming Zeng, Yajun Yang & Xinchao Wang. 2018. Stress Physiology of Tea in the Face of Climate Change. Stress Physiology of Tea in the Face of Climate Change 39 61 .
Rajsekhar Adhikary & Vivekananda Mandal. (2017) l -theanine: A potential multifaceted natural bioactive amide as health supplement. Asian Pacific Journal of Tropical Biomedicine 7:9, pages 842-848.
Crossref
Xinyuan Hao, Litian Li, Yurong Hu, Chao Zhou, Xinchao Wang, Lu Wang, Jianming Zeng & Yajun Yang. (2016) Transcriptomic analysis of the effects of three different light treatments on the biosynthesis of characteristic compounds in the tea plant by RNA-Seq. Tree Genetics & Genomes 12:6.
Crossref

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