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Potential of rooibos, its major C-glucosyl flavonoids, and Z-2-(β-D-glucopyranosyloxy)-3-phenylpropenoic acid in prevention of metabolic syndrome

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Tolulope J. Ashaolu & Samuel A.O. Adeyeye. (2022) African Functional Foods and Beverages: A Review. Journal of Culinary Science & Technology 0:0, pages 1-36.
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Dalene de Beer, Chantelle Human, Marieta van der Rijst & Elizabeth Joubert. (2023) Reaction kinetics of aspalathin degradation and flavanone isomer formation in aqueous model solutions: Effect of temperature, pH and metal chelators. Food Research International 172, pages 113188.
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Naeem Sheik Abdul & Jeanine L. Marnewick. (2023) What has been the focus of Rooibos health research? A bibliometric overview. Journal of Herbal Medicine 37, pages 100615.
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Elizabeth Joubert, Gerda Fouche, Ilze Vermaak, Nduvho Mulaudzi & Weiyang Chen. 2023. The South African Herbal Pharmacopoeia. The South African Herbal Pharmacopoeia 107 152 .
S MAZIBUKO-MBEJE, S MTHEMBU, C MULLER, K ZIQUBU, N MUVHULAWA, R MODIBEDI, L TIANO & P DLUDLA. (2022) Aspalathin Alleviates Skeletal Muscle Insulin Resistance and Mitochondrial Dysfunction. Physiological Research, pages 643-656.
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Ting Xu, Shanshan Hu, Yan Liu, Kang Sun, Liyong Luo & Liang Zeng. (2022) Hawk Tea Flavonoids as Natural Hepatoprotective Agents Alleviate Acute Liver Damage by Reshaping the Intestinal Microbiota and Modulating the Nrf2 and NF-κB Signaling Pathways. Nutrients 14:17, pages 3662.
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Alexander V. Sirotkin. (2021) Rooibos ( Aspalathus linearis ) influence on health and ovarian functions . Journal of Animal Physiology and Animal Nutrition 106:5, pages 995-999.
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Nduvho Mulaudzi, Sandra Combrinck, Ilze Vermaak, Elizabeth Joubert & Alvaro Viljoen. (2022) High performance thin layer chromatography fingerprinting of rooibos (Aspalathus linearis) and honeybush (Cyclopia genistoides, Cyclopia intermedia and Cyclopia subternata) teas. Journal of Applied Research on Medicinal and Aromatic Plants 30, pages 100378.
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Omer I. Fantoukh, Yan-Hong Wang, Abidah Parveen, Mohammed F. Hawwal, Zulfiqar Ali, Gadah A. Al-Hamoud, Amar G. Chittiboyina, Elizabeth Joubert, Alvaro Viljoen & Ikhlas A. Khan. (2022) Chemical Fingerprinting Profile and Targeted Quantitative Analysis of Phenolic Compounds from Rooibos Tea (Aspalathus linearis) and Dietary Supplements Using UHPLC-PDA-MS. Separations 9:7, pages 159.
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Ndivhuwo Muvhulawa, Phiwayinkosi V. Dludla, Khanyisani Ziqubu, Sinenhlanhla X.H. Mthembu, Fikile Mthiyane, Bongani B. Nkambule & Sithandiwe E. Mazibuko-Mbeje. (2022) Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature. Pharmacological Research 178, pages 106163.
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Sybrand Engelbrecht Smit, Claudine Manirafasha, Erna Marais, Rabia Johnson & Barbara Huisamen. (2020) Cardioprotective Function of Green Rooibos (Aspalathus linearis) Extract Supplementation in Ex Vivo Ischemic Prediabetic Rat Hearts. Planta Medica 88:01, pages 62-78.
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O.M. Areo, J.O. Olowoyo, L.S. Sethoga, O.A. Adebo & P.B Njobeh. (2022) Determination of pesticide residues in rooibos (Aspalathus linearis) teas in South Africa. Toxicology Reports 9, pages 852-857.
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Alexander V. Sirotkin & Adriana Kolesarova. 2022. Environmental Contaminants and Medicinal Plants Action on Female Reproduction. Environmental Contaminants and Medicinal Plants Action on Female Reproduction 81 243 .
Christo J. F. Muller, Elizabeth Joubert, Nireshni Chellan, Yutaka Miura & Kazumi Yagasaki. (2021) New Insights into the Efficacy of Aspalathin and Other Related Phytochemicals in Type 2 Diabetes—A Review. International Journal of Molecular Sciences 23:1, pages 356.
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Sushil K. Chaudhary, Maxleene Sandasi, Felix Makolo, Fanie R. van Heerden & Alvaro M. Viljoen. (2021) Aspalathin: a rare dietary dihydrochalcone from Aspalathus linearis (rooibos tea). Phytochemistry Reviews 20:6, pages 1161-1192.
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Sinenhlanhla Mthembu, Christo Muller, Phiwayinkosi Dludla, Evelyn Madoroba, Abidemi Kappo & Sithandiwe Mazibuko-Mbeje. (2021) Rooibos Flavonoids, Aspalathin, Isoorientin, and Orientin Ameliorate Antimycin A-Induced Mitochondrial Dysfunction by Improving Mitochondrial Bioenergetics in Cultured Skeletal Muscle Cells. Molecules 26:20, pages 6289.
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Sithandiwe E. Mazibuko-Mbeje, Sinenhlanhla X.H. Mthembu, Andani Tshiitamune, Ndivhuwo Muvhulawa, Fikile T. Mthiyane, Khanyisani Ziqubu, Christo J.F. Muller & Phiwayinkosi V. Dludla. (2021) Orientin Improves Substrate Utilization and the Expression of Major Genes Involved in Insulin Signaling and Energy Regulation in Cultured Insulin-Resistant Liver Cells. Molecules 26:20, pages 6154.
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Shinji Kondo, Shin-ichi Adachi, Fumiaki Yoshizawa & Kazumi Yagasaki. (2021) Antidiabetic Effect of Taxifolin in Cultured L6 Myotubes and Type 2 Diabetic Model KK-Ay/Ta Mice with Hyperglycemia and Hyperuricemia. Current Issues in Molecular Biology 43:3, pages 1293-1306.
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Beata Zawisza, Marcin Musielak, Dalene de Beer, Elizabeth Joubert & Beata Walczak. (2021) Non-destructive elemental analysis of herbal teas from South Africa. Journal of Food Composition and Analysis 102, pages 104041.
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Chantelle Human, Dalene de Beer, Magdalena Muller, Marieta van der Rijst, Marique Aucamp, Andreas Tredoux, André de Villiers & Elizabeth Joubert. (2021) Shelf-Life Stability of Ready-to-Use Green Rooibos Iced Tea Powder—Assessment of Physical, Chemical, and Sensory Properties. Molecules 26:17, pages 5260.
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Azza Fahmy, Gehan Labib Abuelenain, Nesma Rasheed & Amr Abdou. (2021) ‘de Novo’ repurposing of Daflon as anti-intestinal parasitic drug in experimental giardiasis. Experimental Parasitology 226-227, pages 108124.
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Sinenhlanhla X. H. Mthembu, Phiwayinkosi V. Dludla, Khanyisani Ziqubu, Tawanda M. Nyambuya, Abidemi P. Kappo, Evelyn Madoroba, Thembeka A. Nyawo, Bongani B. Nkambule, Sonia Silvestri, Christo J. F. Muller & Sithandiwe E. Mazibuko-Mbeje. (2021) The Potential Role of Polyphenols in Modulating Mitochondrial Bioenergetics within the Skeletal Muscle: A Systematic Review of Preclinical Models. Molecules 26:9, pages 2791.
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Ishaku Leo Elisha & Alvaro Viljoen. (2021) Trends in Rooibos Tea (Aspalathus linearis) research (1994–2018): A scientometric assessment. South African Journal of Botany 137, pages 159-170.
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Nils Mertens, Thomas Heymann & Marcus A. Glomb. (2020) Oxidative Fragmentation of Aspalathin Leads to the Formation of Dihydrocaffeic Acid and the Related Lysine Amide Adduct. Journal of Agricultural and Food Chemistry 68:46, pages 13111-13120.
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Magdalena Muller, Dalene De Beer, Cristina Truzzi, Anna Annibaldi, Patricia Carloni, Federico Girolametti, Elisabetta Damiani & Elizabeth Joubert. (2020) Cold brewing of rooibos tea affects its sensory profile and physicochemical properties compared to regular hot, and boiled brewing. LWT 132, pages 109919.
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Emily Amor Stander, Wesley Williams, Yamkela Mgwatyu, Peter van Heusden, Fanie Rautenbach, Jeanine Marnewick, Marilize Le Roes-Hill & Uljana Hesse. (2020) Transcriptomics of the Rooibos (Aspalathus linearis) Species Complex. BioTech 9:4, pages 19.
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Morteza Sadeghi & Mohammad Ali Zarei. (2020) Molecular docking studies of some flavone analogues as α-Glucosidase inhibitors. Journal of Medicinal Plants 19:75, pages 55-64.
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Khanyisani Ziqubu, Phiwayinkosi V. Dludla, Elizabeth Joubert, Christo J.F. Muller, Johan Louw, Luca Tiano, Bongani B. Nkambule, Abidemi P. Kappo & Sithandiwe E. Mazibuko-Mbeje. (2020) Isoorientin: A dietary flavone with the potential to ameliorate diverse metabolic complications. Pharmacological Research 158, pages 104867.
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Phiwayinkosi V. Dludla, Rabia Johnson, Sithandiwe E. Mazibuko-Mbeje, Christo J.F. Muller, Johan Louw, Elizabeth Joubert, Patrick Orlando, Sonia Silvestri, Nireshni Chellan, Bongani B. Nkambule, M. Faadiel Essop & Luca Tiano. (2020) Fermented rooibos extract attenuates hyperglycemia-induced myocardial oxidative damage by improving mitochondrial energetics and intracellular antioxidant capacity. South African Journal of Botany 131, pages 143-150.
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Rukayat D Elegbede, Margaret O Ilomuanya, Abimbola A Sowemimo, Amarachi Nneji, Elizabeth Joubert, Dalene de Beer, Trevor Koekemoer & Maryna van van de Venter. (2020) Effect of fermented and green Aspalathus linearis extract loaded hydrogel on surgical wound healing in Sprague Dawley rats. Wound Medicine 29, pages 100186.
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Sithandiwe E. Mazibuko-Mbeje, Khanyisani Ziqubu, Phiwayinkosi V. Dludla, Luca Tiano, Sonia Silvestri, Patrick Orlando, Thembeka A. Nyawo, Johan Louw, Abidemi P. Kappo & Christo J.F. Muller. (2020) Isoorientin ameliorates lipid accumulation by regulating fat browning in palmitate-exposed 3T3-L1 adipocytes. Metabolism Open 6, pages 100037.
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Margaret O. Ilomuanya, Adannaya C. Adebona, Weiguang Wang, Abimbola Sowemimo, Chioma L. Eziegbo, Boladale O. Silva, Samson O. Adeosun, Elizabeth Joubert & Dalene De Beer. (2020) Development and characterization of collagen-based electrospun scaffolds containing silver sulphadiazine and Aspalathus linearis extract for potential wound healing applications. SN Applied Sciences 2:5.
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Amsha Viraragavan, Nokulunga Hlengwa, Dalene de Beer, Sylvia Riedel, Neil Miller, Sandra Bowles, Beata Walczak, Christo Muller & Elizabeth Joubert. (2020) Model development for predicting in vitro bio-capacity of green rooibos extract based on composition for application as screening tool in quality control . Food & Function 11:4, pages 3084-3094.
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Phiwayinkosi V. Dludla, Christo J. F. Muller, Johan Louw, Sithandiwe E. Mazibuko-Mbeje, Luca Tiano, Sonia Silvestri, Patrick Orlando, Fabio Marcheggiani, Ilenia Cirilli, Nireshni Chellan, Samira Ghoor, Bongani B. Nkambule, M. Faadiel Essop, Barbara Huisamen & Rabia Johnson. (2020) The Combination Effect of Aspalathin and Phenylpyruvic Acid-2-O-β-D-glucoside from Rooibos against Hyperglycemia-Induced Cardiac Damage: An In Vitro Study. Nutrients 12:4, pages 1151.
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Shih-Han Huang, Yung-Hsi Kao, Christo J.F. Muller, Elizabeth Joubert & Chih-Pin Chuu. (2020) Aspalathin-rich green Aspalathus linearis extract suppresses migration and invasion of human castration-resistant prostate cancer cells via inhibition of YAP signaling. Phytomedicine 69, pages 153210.
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Yamkela Mgwatyu, Allison Anne Stander, Stephan Ferreira, Wesley Williams & Uljana Hesse. (2020) Rooibos (Aspalathus linearis) Genome Size Estimation Using Flow Cytometry and K-Mer Analyses. Plants 9:2, pages 270.
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Oelfah Patel, Christo J.F. Muller, Elizabeth Joubert, Bernd Rosenkranz, Malcolm J.C. Taylor, Johan Louw & Charles Awortwe. (2019) Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats. Frontiers in Pharmacology 10.
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Elisabetta Damiani, Patricia Carloni, Gabriele Rocchetti, Biancamaria Senizza, Luca Tiano, Elizabeth Joubert, Dalene de Beer & Luigi Lucini. (2019) Impact of Cold versus Hot Brewing on the Phenolic Profile and Antioxidant Capacity of Rooibos (Aspalathus linearis) Herbal Tea. Antioxidants 8:10, pages 499.
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Rieko Arakaki, Aya Ushio, Satoru Kisoda, Mami Sato, Yoshitaka Nakamura, Kanako Yuyama, Riho Tateyama, Satoru Morishita, Noriyuki Monoi, Yasusei Kudo & Naozumi Ishimaru. (2019) Novel effects of rooibos extract on tear and saliva secretion mediated by the muscarinic acetylcholine receptor 3 in mice. Journal of Oral Biosciences 61:3, pages 179-182.
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J.I. Layman, D.L. Pereira, N. Chellan, B. Huisamen & S.H. Kotzé. (2019) A histomorphometric study on the hepatoprotective effects of a green rooibos extract in a diet-induced obese rat model. Acta Histochemica 121:5, pages 646-656.
Crossref
Justyna Pyrzanowska, Izabela Fecka, Dagmara Mirowska-Guzel, Ilona Joniec-Maciejak, Kamilla Blecharz-Klin, Agnieszka Piechal, Ewa Wojnar & Ewa Widy-Tyszkiewicz. (2019) Long-term administration of Aspalathus linearis infusion affects spatial memory of adult Sprague-Dawley male rats as well as increases their striatal dopamine content. Journal of Ethnopharmacology 238, pages 111881.
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Sithandiwe E. Mazibuko-Mbeje, Phiwayinkosi V. Dludla, Rabia Johnson, Elizabeth Joubert, Johan Louw, Khanyisani Ziqubu, Luca Tiano, Sonia Silvestri, Patrick Orlando, Andy R. Opoku & Christo J. F. Muller. (2019) Aspalathin, a natural product with the potential to reverse hepatic insulin resistance by improving energy metabolism and mitochondrial respiration. PLOS ONE 14:5, pages e0216172.
Crossref
Saori Nishimachi, Takao Iwai, Yoshitaka Nakamura, Kanako Yuyama-Masuda, Takuya Tsutsui, Noriyuki Monoi, Akira Uchiyama & Seiji Nakamura. (2019) Rooibos (Aspalathus linearis) extract, containing eriodictyol-6-C-β-d-glucoside as the active component, stimulates exocrine glands via the M3 muscarinic acetylcholine receptor. Journal of Functional Foods 55, pages 248-254.
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Maria A. Stander, Elizabeth Joubert & Dalene De Beer. (2019) Revisiting the caffeine-free status of rooibos and honeybush herbal teas using specific MRM and high resolution LC-MS methods. Journal of Food Composition and Analysis 76, pages 39-43.
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Chantelle Human, Dalene De Beer, Marieta Van Der Rijst, Marique Aucamp & Elizabeth Joubert. (2019) Electrospraying as a suitable method for nanoencapsulation of the hydrophilic bioactive dihydrochalcone, aspalathin. Food Chemistry 276, pages 467-474.
Crossref
Kazumi Yagasaki. 2019. Nutrition and Skeletal Muscle. Nutrition and Skeletal Muscle 421 438 .
Solomon Habtemariam. 2019. Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases. Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases 907 941 .
Nonhlakanipho F. Sangweni, Phiwayinkosi V. Dludla, Rebamang A. Mosa, Abidemi P. Kappo, Andy Opoku, Christo J. F. Muller & Rabia Johnson. (2018) Lanosteryl triterpenes from Protorhus longifolia as a cardioprotective agent: a mini review. Heart Failure Reviews 24:1, pages 155-166.
Crossref
Sithandiwe Eunice Mazibuko-Mbeje, Phiwayinkosi V. Dludla, Bongani B. Nkambule, Nnini Obonye & Johan Louw. 2018. Muscle Cell and Tissue - Current Status of Research Field. Muscle Cell and Tissue - Current Status of Research Field.
Neil Miller, Dalene De Beer, Marique Aucamp, Christiaan J. Malherbe & Elizabeth Joubert. (2018) Inulin as microencapsulating agent improves physicochemical properties of spray-dried aspalathin-rich green rooibos (Aspalathus linearis) extract with α-glucosidase inhibitory activity. Journal of Functional Foods 48, pages 400-409.
Crossref
Phiwayinkosi V. Dludla, Elizabeth Joubert, Christo J.F. Muller, Johan Louw & Rabia Johnson. (2017) Hyperglycemia-induced oxidative stress and heart disease-cardioprotective effects of rooibos flavonoids and phenylpyruvic acid-2-O-β-D-glucoside. Nutrition & Metabolism 14:1.
Crossref
B.-E. Van Wyk & B. Gorelik. (2017) The history and ethnobotany of Cape herbal teas. South African Journal of Botany 110, pages 18-38.
Crossref
M. Viljoen, M. Muller, D. De Beer & E. Joubert. (2017) Identification of broad-based sensory attributes driving consumer preference of ready-to-drink rooibos iced tea with increased aspalathin content. South African Journal of Botany 110, pages 177-183.
Crossref
Sandra Bowles, Elizabeth Joubert, Dalene de Beer, Johan Louw, Christel Brunschwig, Mathew Njoroge, Nina Lawrence, Lubbe Wiesner, Kelly Chibale & Christo Muller. (2017) Intestinal Transport Characteristics and Metabolism of C-Glucosyl Dihydrochalcone, Aspalathin. Molecules 22:4, pages 554.
Crossref
Federico Marini, Dalene de Beer, Nico A. Walters, André de Villiers, Elizabeth Joubert & Beata Walczak. (2017) Multivariate analysis of variance of designed chromatographic data. A case study involving fermentation of rooibos tea. Journal of Chromatography A 1489, pages 115-125.
Crossref
Nico A. Walters, André de Villiers, Elizabeth Joubert & Dalene de Beer. (2017) Improved HPLC method for rooibos phenolics targeting changes due to fermentation. Journal of Food Composition and Analysis 55, pages 20-29.
Crossref

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