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Original Articles

Do marine algal polyphenols have antidiabetic, antihyperlipidemic or anti-inflammatory effects in humans? A systematic review

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Kristin Krueger, Elke Boehme, Alexa Karina Klettner & Marietta Zille. (2022) The potential of marine resources for retinal diseases: a systematic review of the molecular mechanisms. Critical Reviews in Food Science and Nutrition 62:27, pages 7518-7560.
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Tosin A. Olasehinde, Leonard V. Mabinya, Ademola O. Olaniran & Anthony I. Okoh. (2019) Chemical characterization of sulfated polysaccharides from Gracilaria gracilis and Ulva lactuca and their radical scavenging, metal chelating, and cholinesterase inhibitory activities. International Journal of Food Properties 22:1, pages 100-110.
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Shahla Rezaei, Saeid Doaei, Reza Tabrizi, Saeed Ghobadi, Morteza Zare, Maryam Gholamalizadeh & Zohreh Mazloom. (2023) The effects of macro‐algae supplementation on serum lipid, glycaemic control and anthropometric indices: A systematic review and meta‐analysis of clinical trials. Endocrinology, Diabetes & Metabolism.
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Pradipkumar Vaghela, Khanjan Trivedi, K.G. Vijay Anand, Jibananand Nayak, Divya Vyas & Arup Ghosh. (2023) Aqueous homogenate of fresh Ulva lactuca for ameliorating nutrient deficiency—A nutraceutical alternative to using whole seaweeds. Algal Research 74, pages 103211.
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Aleksandra Konic Ristic, Sinead Ryan, Maha Attjioui, Shane O’Connell & Eileen R. Gibney. (2023) Effects of an Extract of the Brown Seaweed Ascophylum nodosum on Postprandial Glycaemic Control in Healthy Subjects: A Randomized Controlled Study. Marine Drugs 21:6, pages 337.
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Lara Diego-González & Rosana Simón-Vázquez. 2023. Functional Ingredients from Algae for Foods and Nutraceuticals. Functional Ingredients from Algae for Foods and Nutraceuticals 593 615 .
Shaohui Wang, Qinyun Du, Xianli Meng & Yi Zhang. (2022) Natural polyphenols: a potential prevention and treatment strategy for metabolic syndrome. Food & Function 13:19, pages 9734-9753.
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Ziqi Su, Kunlong Li, Xiaowei Luo, Yongyan Zhu, Shao-Yu Mai, Quanhong Zhu, Bin Yang, Xuefeng Zhou & Huaming Tao. (2022) Aromatic Acids and Leucine Derivatives Produced from the Deep-Sea Actinomycetes Streptomyces chumphonensis SCSIO15079 with Antihyperlipidemic Activities. Marine Drugs 20:4, pages 259.
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Natalya N. Besednova, Boris G. Andryukov, Tatyana S. Zaporozhets, Tatyana A. Kuznetsova, Sergey P. Kryzhanovsky, Svetlana P. Ermakova, Irina V. Galkina & Mikhail Yu. Shchelkanov. (2022) Molecular Targets of Brown Algae Phlorotannins for the Therapy of Inflammatory Processes of Various Origins. Marine Drugs 20:4, pages 243.
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Julianna Karla Santana Andrade, Romy Gleyse Chagas Barros, Ubatã Corrêa Pereira, Juliete Pedreira Nogueira, Nayjara Carvalho Gualberto, Christean Santos de Oliveira, Saravanan Shanmugam & Narendra Narain. (2022) Bioaccessibility of bioactive compounds after in vitro gastrointestinal digestion and probiotics fermentation of Brazilian fruits residues with antioxidant and antidiabetic potential. LWT 153, pages 112469.
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Julianna Karla Santana Andrade, Romy Gleyse Chagas Barros, Nayjara Carvalho Gualberto, Christean Santos de Oliveira, Saravanan Shanmugam & Narendra Narain. (2022) Influence of in vitro gastrointestinal digestion and probiotic fermentation on the bioaccessibility of gallic acid and on the antioxidant potential of Brazilian fruit residues. LWT 153, pages 112436.
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Ashvinder Kaur, Gaganjot Kaur, Reetu & Monika Prakash Rai. 2022. Algal Biotechnology. Algal Biotechnology 283 303 .
Margaret Murray, Aimee L Dordevic, Kate Cox, Andrew Scholey, Lisa Ryan & Maxine P Bonham. (2021) Twelve weeks’ treatment with a polyphenol-rich seaweed extract increased HDL cholesterol with no change in other biomarkers of chronic disease risk in overweight adults: A placebo-controlled randomized trial. The Journal of Nutritional Biochemistry 96, pages 108777.
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Durairaj Karthick Rajan, Kannan Mohan, Shubing Zhang & Abirami Ramu Ganesan. (2021) Dieckol: a brown algal phlorotannin with biological potential. Biomedicine & Pharmacotherapy 142, pages 111988.
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Aswathy Udayan, Ashutosh Kumar Pandey, Pooja Sharma, Nidhin Sreekumar & Sunil Kumar. (2021) Emerging industrial applications of microalgae: challenges and future perspectives. Systems Microbiology and Biomanufacturing 1:4, pages 411-431.
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Xiangxi Meng, Qinyu Li, Ruyu Shi, Jiayin Chang, Hong Chang & Minhui Li. (2021) Food supplements could be an effective improvement of diabetes mellitus: a review. Journal of Future Foods 1:1, pages 67-81.
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Zhejie Chen, Mohamed A. Farag, Zhangfeng Zhong, Chen Zhang, Yu Yang, Shengpeng Wang & Yitao Wang. (2021) Multifaceted role of phyto-derived polyphenols in nanodrug delivery systems. Advanced Drug Delivery Reviews 176, pages 113870.
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Qing Zhang, Xiao-Yun Fan, Ying-Jia Cao, Ting-Ting Zheng, Wen-Jian Cheng, Li-Jiao Chen, Xu-Cong Lv, Li Ni, Ping-Fan Rao & Peng Liang. (2021) The beneficial effects of Lactobacillus brevis FZU0713-fermented Laminaria japonica on lipid metabolism and intestinal microbiota in hyperlipidemic rats fed with a high-fat diet . Food & Function 12:16, pages 7145-7160.
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Leslie Gager, Fanny Lalegerie, Solène Connan & Valérie Stiger‐Pouvreau. 2021. Recent Advances in Micro and Macroalgal Processing. Recent Advances in Micro and Macroalgal Processing 278 334 .
Aránzazu Bocanegra, Adrián Macho-González, Alba Garcimartín, Juana Benedí & Francisco José Sánchez-Muniz. (2021) Whole Alga, Algal Extracts, and Compounds as Ingredients of Functional Foods: Composition and Action Mechanism Relationships in the Prevention and Treatment of Type-2 Diabetes Mellitus. International Journal of Molecular Sciences 22:8, pages 3816.
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Lei Chen, Run Liu, Xin He, Shengjie Pei & Duo Li. (2021) Effects of brown seaweed polyphenols, a class of phlorotannins, on metabolic disorders via regulation of fat function . Food & Function 12:6, pages 2378-2388.
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Daniela Gabbia & Sara De Martin. (2020) Brown Seaweeds for the Management of Metabolic Syndrome and Associated Diseases. Molecules 25:18, pages 4182.
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Olesya S. Malyarenko, Tatiana I. Imbs & Svetlana P. Ermakova. (2020) In Vitro Anticancer and Radiosensitizing Activities of Phlorethols from the Brown Alga Costaria costata. Molecules 25:14, pages 3208.
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Giovanna Bermano, Teodora Stoyanova, Franck Hennequart & Cherry L. Wainwright. 2020. Pharmacological Advances in Natural Product Drug Discovery. Pharmacological Advances in Natural Product Drug Discovery 205 256 .
Hoichi Amano, Yoshiharu Fukuda, Megu Y. Baden & Ichiro Kawachi. (2020) Is work engagement associated with healthier dietary patterns? A cross‐sectional study. Journal of Occupational Health 62:1.
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Lijun Sun, Fredrick J. Warren & Michael J. Gidley. (2019) Natural products for glycaemic control: Polyphenols as inhibitors of alpha-amylase. Trends in Food Science & Technology 91, pages 262-273.
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Di Zhang, Ying Wang, Xiaoxia Sun, Yixiang Liu, Yaojie Zhou, Hyeon‐Cheol Shin, Yong Wang, Lingqin Shen, Chengtao Wang, Shaoyun Wang & Xiaobo Zou. (2019) Voltammetric, spectroscopic, and cellular characterization of redox functionality of eckol and phlorofucofuroeckol‐A: A comparative study. Journal of Food Biochemistry 43:7.
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Paul Cherry, Cathal O’Hara, Pamela J Magee, Emeir M McSorley & Philip J Allsopp. (2019) Risks and benefits of consuming edible seaweeds. Nutrition Reviews 77:5, pages 307-329.
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Margaret Murray, Aimee Dordevic, Lisa Ryan & Maxine Bonham. (2019) A Single-Dose of a Polyphenol-Rich Fucus Vesiculosus Extract is Insufficient to Blunt the Elevated Postprandial Blood Glucose Responses Exhibited by Healthy Adults in the Evening: A Randomised Crossover Trial. Antioxidants 8:2, pages 49.
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Guopeng Lin, Xiaoyan Liu, Xin Yan, Dan Liu, Chengfeng Yang, Bin Liu, Yifan Huang & Chao Zhao. (2018) Role of Green Macroalgae Enteromorpha Prolifera Polyphenols in the Modulation of Gene Expression and Intestinal Microflora Profiles in Type 2 Diabetic Mice. International Journal of Molecular Sciences 20:1, pages 25.
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Margaret Murray, Aimee L Dordevic, Katherine H M Cox, Andrew Scholey, Lisa Ryan & Maxine P Bonham. (2018) Study protocol for a double-blind randomised controlled trial investigating the impact of 12 weeks supplementation with a Fucus vesiculosus extract on cholesterol levels in adults with elevated fasting LDL cholesterol who are overweight or have obesity . BMJ Open 8:12, pages e022195.
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Manuel Gómez-Guzmán, Alba Rodríguez-Nogales, Francesca Algieri & Julio Gálvez. (2018) Potential Role of Seaweed Polyphenols in Cardiovascular-Associated Disorders. Marine Drugs 16:8, pages 250.
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Daniel Rico, Ana Belén Martín Diana, Iñaki Milton-Laskibar, Alfredo Fernández-Quintela, Jose Manuel Silván, Dilip K. Rai, Alka Choudhary, Elena Peñas, Daniel Antonio de Luis & Cristina Martínez-Villaluenga. (2018) Characterization and in vitro evaluation of seaweed species as potential functional ingredients to ameliorate metabolic syndrome. Journal of Functional Foods 46, pages 185-194.
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Margaret Murray, Aimee Dordevic, Lisa Ryan & Maxine Bonham. (2018) The Impact of a Single Dose of a Polyphenol-Rich Seaweed Extract on Postprandial Glycaemic Control in Healthy Adults: A Randomised Cross-Over Trial. Nutrients 10:3, pages 270.
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Sihui Ma, Koichi Yada, Hyunjin Lee, Youichi Fukuda, Akira Iida & Katsuhiko Suzuki. (2017) Taheebo Polyphenols Attenuate Free Fatty Acid-Induced Inflammation in Murine and Human Macrophage Cell Lines As Inhibitor of Cyclooxygenase-2. Frontiers in Nutrition 4.
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