Advanced search
Publication Cover
Critical Reviews in Food Science and Nutrition Volume 62, 2022 - Issue 1
Submit an article Journal homepage
894
Views
19
CrossRef citations to date
0
Altmetric
Reviews

Treatment with the flavonoid 7,8-Dihydroxyflavone: a promising strategy for a constellation of body and brain disorders

Marco Emilia Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, ItalyView further author information
,
Sandra Guidia Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, ItalyView further author information
,
Beatrice Uguagliatia Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, ItalyView further author information
,
Andrea Giacominia Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, ItalyView further author information
,
Renata Bartesaghia Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, ItalyCorrespondence[email protected] [email protected]
View further author information
&
Fiorenza Stagnib Department for Life Quality Studies, University of Bologna, Rimini, ItalyCorrespondence[email protected] [email protected]
View further author information
Pages 13-50 | Published online: 11 Sep 2020

Citations (19)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Mansi Varshney, Bhavna Kumar, Vijay Singh Rana & Neeraj K. Sethiya. (2023) An overview on therapeutic and medicinal potential of poly-hydroxy flavone viz. Heptamethoxyflavone, Kaempferitrin, Vitexin and Amentoflavone for management of Alzheimer’s and Parkinson’s diseases: a critical analysis on mechanistic insight. Critical Reviews in Food Science and Nutrition 63:16, pages 2749-2772.
Read now
Zhi-Jing Ni, Yi-Ge Zhang, Sheng-Xiong Chen, Kiran Thakur, Shaoyun Wang, Jian-Guo Zhang, Ya-Fang Shang & Zhao-Jun Wei. (2022) Exploration of walnut components and their association with health effects. Critical Reviews in Food Science and Nutrition 62:19, pages 5113-5129.
Read now

Articles from other publishers (17)

Yu-shan Chen, Si-ming Zhang, Wei Tan, Qiong Zhu, Chao-xiong Yue, Peng Xiang, Jin-quan Li, Zhen Wei & Yan Zeng. (2023) Early 7,8-Dihydroxyflavone Administration Ameliorates Synaptic and Behavioral Deficits in the Young FXS Animal Model by Acting on BDNF-TrkB Pathway. Molecular Neurobiology 60:5, pages 2539-2552.
Crossref
Soojung Yoon, Hamid Iqbal, Sun Mi Kim & Mirim Jin. (2023) Phytochemicals That Act on Synaptic Plasticity as Potential Prophylaxis against Stress-Induced Depressive Disorder. Biomolecules & Therapeutics 31:2, pages 148-160.
Crossref
Peng-Zhou Hang, Jie Liu, Jia-Pan Wang, Feng-Feng Li, Pei-Feng Li, Qing-Nan Kong, Jing Shi, Hong-Yu Ji, Zhi-Min Du & Jing Zhao. (2023) 7,8-Dihydroxyflavone alleviates cardiac fibrosis by restoring circadian signals via downregulating Bmal1/Akt pathway. European Journal of Pharmacology 938, pages 175420.
Crossref
Arzu Öztürk Kesebir. (2022) Purification and Characterization of Lipoxygenase from Walnuts (Juglans Regia) and Investigation of the Effects of Some Phenolic Compounds on the Activity. ChemistrySelect 7:46.
Crossref
Nan Bian, Xiangqian Chen, Xinran Ren, Zishu Yu, Mengli Jin, Xiaoyu Chen, Chang Liu, Yanhe Luan, Lin Wei, Ying Chen, Wu Song, Yicheng Zhao, Bingmei Wang, Tao Jiang, Chi Zhang, Zunhua Shu, Xin Su & Li Wang. (2022) 7,8-Dihydroxyflavone attenuates the virulence of Staphylococcus aureus by inhibiting alpha-hemolysin. World Journal of Microbiology and Biotechnology 38:11.
Crossref
Annunziata Guarino, Barbara Bettegazzi, Nimra Aziz, Mario Barbieri, Daniela Bochicchio, Lucia Crippa, Pietro Marino, Maddalena Sguizzato, Marie Soukupova, Silvia Zucchini & Michele Simonato. (2022) Low-dose 7,8-Dihydroxyflavone Administration After Status Epilepticus Prevents Epilepsy Development. Neurotherapeutics 19:6, pages 1951-1965.
Crossref
Safira Dita ArvianaYuyun YueniwatiMasruroh RahayuMokhamad Fahmi Rizki Syaban. (2022) 7,8-dihydroxyflavone as a Neuroprotective agent in Ischemic Stroke through the Regulation of HIF-1α Protein. Research Journal of Pharmacy and Technology, pages 3980-3986.
Crossref
Shaojie Yang & Guoqi Zhu. (2022) 7,8-Dihydroxyflavone and Neuropsychiatric Disorders: A Translational Perspective from the Mechanism to Drug Development. Current Neuropharmacology 20:8, pages 1479-1497.
Crossref
Selma CIRRIK, Gulay HACIOĞLU, Emine Gülçeri GÜLEÇ PEKER, Hatıce KESER & Selcen ABIDIN. (2022) Yaşa bağlı oksidatif stres ve nitrik oksid azalışında 7,8-dihidroksiflavonun etkisi. Pamukkale Medical Journal.
Crossref
Danil Peregud, Alexey Kvichansky, Natalia Shirobokova, Mikhail Stepanichev & Natalia Gulyaeva. (2022) 7,8-DHF enhances SHH in the hippocampus and striatum during early abstinence but has minor effects on alcohol intake in IA2BC paradigm and abstinence-related anxiety-like behavior in rats. Neuroscience Letters 781, pages 136671.
Crossref
Yuan-yuan Fang, Miao Luo, Shuang Yue, Yin Han, Huo-jun Zhang, Yu-hao Zhou, Kui Liu & Hui-guo Liu. (2021) 7,8-Dihydroxyflavone protects retinal ganglion cells against chronic intermittent hypoxia-induced oxidative stress damage via activation of the BDNF/TrkB signaling pathway. Sleep and Breathing 26:1, pages 287-295.
Crossref
Daniela Valenti, Fiorenza Stagni, Marco Emili, Sandra Guidi, Renata Bartesaghi & Rosa Anna Vacca. (2021) Impaired Brain Mitochondrial Bioenergetics in the Ts65Dn Mouse Model of Down Syndrome Is Restored by Neonatal Treatment with the Polyphenol 7,8-Dihydroxyflavone. Antioxidants 11:1, pages 62.
Crossref
Bruce R. Southey, Marissa R. Keever-Keigher, Haley E. Rymut, Laurie A. Rund, Rodney W. Johnson & Sandra L. Rodriguez-Zas. (2021) Disruption of Alternative Splicing in the Amygdala of Pigs Exposed to Maternal Immune Activation. Immuno 1:4, pages 499-517.
Crossref
Alejandro Gallego-Ortega, Beatriz Vidal-Villegas, María Norte-Muñoz, Manuel Salinas-Navarro, Marcelino Avilés-Trigueros, María Villegas-Pérez & Manuel Vidal-Sanz. (2021) 7,8-Dihydroxiflavone Maintains Retinal Functionality and Protects Various Types of RGCs in Adult Rats with Optic Nerve Transection. International Journal of Molecular Sciences 22:21, pages 11815.
Crossref
Caridad Galindo-Romero, Beatriz Vidal-Villegas, Javier Asís-Martínez, Fernando Lucas-Ruiz, Alejandro Gallego-Ortega & Manuel Vidal-Sanz. (2021) 7,8-Dihydroxiflavone Protects Adult Rat Axotomized Retinal Ganglion Cells through MAPK/ERK and PI3K/AKT Activation. International Journal of Molecular Sciences 22:19, pages 10896.
Crossref
Li Zuo, Chunfang Dai, Lilin Yi & Zhifang Dong. (2021) 7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson’s disease. Cell Death Discovery 7:1.
Crossref
Piotr Pankiewicz, Marcin Szybiński, Katarzyna Kisielewska, Filip Gołębiowski, Patryk Krzemiński, Izabela Rutkowska-Włodarczyk, Rafał Moszczyński-Pętkowski, Lidia Gurba-Bryśkiewicz, Monika Delis, Krzysztof Mulewski, Damian Smuga, Jakub Dominowski, Artur Janusz, Michał Górka, Krzysztof Abramski, Agnieszka Napiórkowska, Marcin Nowotny, Krzysztof Dubiel, Katarzyna Kalita, Maciej Wieczorek, Jerzy Pieczykolan & Mikołaj Matłoka. (2021) Do Small Molecules Activate the TrkB Receptor in the Same Manner as BDNF? Limitations of Published TrkB Low Molecular Agonists and Screening for Novel TrkB Orthosteric Agonists. Pharmaceuticals 14:8, pages 704.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.