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Critical Reviews in Toxicology Volume 49, 2019 - Issue 3
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Review Articles

Systematic review and meta-analysis of adverse cardiovascular events associated with proton pump inhibitors used alone or in combination with antiplatelet agents

Nawal FarhatSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; Correspondence[email protected]
,
Yannick FortinSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada;
,
Nisrine HaddadSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada;
,
Nicholas BirkettSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada;
,
Donald R. MattisonSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; ;Risk Sciences International, Ottawa, Canada;
,
Franco MomoliSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada;
,
Shi Wu WenSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; ;Ottawa Hospital Research Institute, Ottawa, Canada
&
Daniel KrewskiSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; ;Risk Sciences International, Ottawa, Canada;
show all
Pages 215-261 | Received 07 Jul 2018, Accepted 11 Feb 2019, Published online: 13 Jun 2019

Citations (12)

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Eleftherios Teperikidis, Aristi Boulmpou, Victoria Potoupni, Satyabrata Kundu, Balpreet Singh & Christodoulos Papadopoulos. (2023) Does the long-term administration of proton pump inhibitors increase the risk of adverse cardiovascular outcomes? A ChatGPT powered umbrella review. Acta Cardiologica 78:9, pages 980-988.
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Inès Ben Ghezala, Maxime Luu & Marc Bardou. (2022) An update on drug–drug interactions associated with proton pump inhibitors. Expert Opinion on Drug Metabolism & Toxicology 18:5, pages 337-346.
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Articles from other publishers (10)

Tingting Geng, Jun-Xiang Chen, Yan-Feng Zhou, Qi Lu, Zhenzhen Wan, Liegang Liu, An Pan & Gang Liu. (2023) Proton Pump Inhibitor Use and Risks of Cardiovascular Disease and Mortality in Patients With Type 2 Diabetes. The Journal of Clinical Endocrinology & Metabolism 108:6, pages e216-e222.
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Naina Mohamed Pakkir Maideen. (2023) Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors. Chonnam Medical Journal 59:2, pages 115.
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Michael Nolde, Nayeon Ahn, Tobias Dreischulte, Evamaria Krause, Florian Güntner, Alexander Günter, Roman Gerlach, Martin Tauscher, Ute Amann, Jakob Linseisen, Christa Meisinger, Sebastian-Edgar Baumeister & Ina-Maria Rückert-Eheberg. (2022) Proton pump inhibitors and the risk of cardiovascular events and cardiovascular mortality: A systematic review and meta-analysis of observational studies. European Journal of Internal Medicine 106, pages 80-89.
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Ju-Young Park, Joonsang Yoo, Jimin Jeon, Jinkwon Kim & Sangwook Kang. (2022) Proton Pump Inhibitors and Risk of Cardiovascular Disease: A Self-Controlled Case Series Study. American Journal of Gastroenterology 117:7, pages 1063-1071.
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Philip O. Katz, Kerry B. Dunbar, Felice H. Schnoll-Sussman, Katarina B. Greer, Rena Yadlapati & Stuart Jon Spechler. (2022) ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease. American Journal of Gastroenterology 117:1, pages 27-56.
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Michael Nolde, Nayeon Ahn, Tobias Dreischulte, Ina‐Maria Rückert‐Eheberg, Florian Güntner, Alexander Günter, Roman Gerlach, Martin Tauscher, Ute Amann, Jakob Linseisen, Christa Meisinger & Sebastian‐Edgar Baumeister. (2021) The long‐term risk for myocardial infarction or stroke after proton pump inhibitor therapy (2008‐2018). Alimentary Pharmacology & Therapeutics 54:8, pages 1033-1040.
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Elizabeth M. Salvo, Nicole C. Ferko, Sarah B. Cash, Ailish Gonzalez & Peter J. Kahrilas. (2021) Umbrella review of 42 systematic reviews with meta‐analyses: the safety of proton pump inhibitors. Alimentary Pharmacology & Therapeutics 54:2, pages 129-143.
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Ying Lian Xiao, Li Ya Zhou, Xiao Hua Hou, Yan Qing Li, Duo Wu Zou & Min Hu Chen. (2021) Chinese expert consensus on gastroesophageal reflux disease in 2020. Journal of Digestive Diseases 22:7, pages 376-389.
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Michael Nolde, Martin Bahls, Nele Friedrich, Marcus Dörr, Tobias Dreischulte, Stephan B. Felix, Ina‐Maria Rückert‐Eheberg, Nayeon Ahn, Ute Amann, Edzard Schwedhelm, Henry Völzke, Markus M. Lerch, Jakob Linseisen, Christa Meisinger & Sebastian E. Baumeister. (2021) Association of proton pump inhibitor use with endothelial function and metabolites of the nitric oxide pathway: A cross‐sectional study. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 41:2, pages 198-204.
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Nawal Farhat, Nicholas Birkett, Nisrine Haddad, Yannick Fortin, Franco Momoli, Shi Wu Wen, Andreas Wielgosz, Doug S. McNair, Donald R. Mattison & Daniel Krewski. (2020) Risk of Adverse Cardiovascular Events Following a Myocardial Infarction in Patients Receiving Combined Clopidogrel and Proton Pump Inhibitor Treatment: A Nested Case–Control Study. Drugs - Real World Outcomes 7:3, pages 191-203.
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