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Christopher Mellor, Consuelo Perez & Julian E. Sale. (2022) Creation and resolution of non-B-DNA structural impediments during replication. Critical Reviews in Biochemistry and Molecular Biology 57:4, pages 412-442.
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Alexandra M Pike, Caitlin M Friend & Stephen P Bell. (2023) Distinct RPA functions promote eukaryotic DNA replication initiation and elongation. Nucleic Acids Research 51:19, pages 10506-10518.
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Crossref
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold & Christopher E. Pearson. (2023) Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability. Cell 186:22, pages 4898-4919.e25.
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Yeyao Wu, Wangmi Fu, Ning Zang & Chun Zhou. (2023) Structural characterization of human RPA70N association with DNA damage response proteins. eLife 12.
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Cory L. Holland, Monica F. Weis, Corbin J. England, Armand M. Berry, Paige D. Hall & L. Kevin Lewis. (2023) Deficiency in homologous recombination is associated with changes in cell cycling and morphology in Saccharomyces cerevisiae. Experimental Cell Research 430:1, pages 113701.
Crossref
Crossref
Luke A. Yates & Xiaodong Zhang. (2023) Phosphoregulation of the checkpoint kinase Mec1ATR. DNA Repair 129, pages 103543.
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Xiaoxiao Wang, Sufang Zhang, Zhongtao Zhang, Nayef A. Mazloum, Ernest Y.C. Lee & Marietta Y.W. Lee. (2023) The DHX9 helicase interacts with human DNA polymerase δ4 and stimulates its activity in D-loop extension synthesis. DNA Repair 128, pages 103513.
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Juan-Manuel Hernandez-Martinez, Rafael Rosell & Oscar Arrieta. (2023) Somatic and germline ATM variants in non-small-cell lung cancer: Therapeutic implications. Critical Reviews in Oncology/Hematology 188, pages 104058.
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Aditi Mukherjee, Zakir Hossain, Esteban Erben, Shuai Ma, Jun Yong Choi & Hee-Sook Kim. (2023) Identification of a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1. Nature Communications 14:1.
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Jiawei Ding, Xiangting Li, Jiangchuan Shen, Yiling Zhao, Shuchen Zhong, Luhua Lai, Hengyao Niu & Zhi Qi. (2023) ssDNA accessibility of Rad51 is regulated by orchestrating multiple RPA dynamics. Nature Communications 14:1.
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Poonam Roshan, Sahiti Kuppa, Jenna R. Mattice, Vikas Kaushik, Rahul Chadda, Nilisha Pokhrel, Brunda R. Tumala, Aparna Biswas, Brian Bothner, Edwin Antony & Sofia Origanti. (2023) An Aurora B-RPA signaling axis secures chromosome segregation fidelity. Nature Communications 14:1.
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Sharon N. Greenwood, Rashmi S. Kulkarni, Michel Mikhail & Brian P. Weiser. (2023) Replication Protein A Enhances Kinetics of Uracil DNA Glycosylase on ssDNA and Across DNA Junctions: Explored with a DNA Repair Complex Produced with SpyCatcher/SpyTag Ligation. ChemBioChem 24:10.
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Vincent Spegg, Andreas Panagopoulos, Merula Stout, Aswini Krishnan, Giordano Reginato, Ralph Imhof, Bernd Roschitzki, Petr Cejka & Matthias Altmeyer. (2023) Phase separation properties of RPA combine high-affinity ssDNA binding with dynamic condensate functions at telomeres. Nature Structural & Molecular Biology 30:4, pages 451-462.
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Divya S Bhat, Eva Malacaria, Ludovica Di Biagi, Mortezaali Razzaghi, Masayoshi Honda, Kathryn F Hobbs, Sarah R Hengel, Pietro Pichierri, M Ashley Spies & Maria Spies. (2023) Therapeutic disruption of RAD52–ssDNA complexation via novel drug-like inhibitors. NAR Cancer 5:2.
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Justin A. Ling, Melissa S. Gildenberg, Masayoshi Honda, Christine M. Kondratick, Maria Spies & M.Todd Washington. (2023) Fork-Remodeling Helicase Rad5 Preferentially Reverses Replication Forks with Gaps in the Leading Strand. Journal of Molecular Biology 435:4, pages 167946.
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Rebeca Bocanegra, María Ortíz-Rodríguez, Lyra Zumeta, Ismael Plaza-G.A.Elías Faro & Borja Ibarra. 2023. History of The Enzymes, Current Topics and Future Perspectives. History of The Enzymes, Current Topics and Future Perspectives
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Divya S. Bhat, M. Ashley Spies & Maria Spies. (2022) A moving target for drug discovery: Structure activity relationship and many genome (de)stabilizing functions of the RAD52 protein. DNA Repair 120, pages 103421.
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Crossref
Shalini Trivedi, Jitka Blazícková & Nicola Silva. (2022) PARG and BRCA1–BARD1 cooperative function regulates DNA repair pathway choice during gametogenesis. Nucleic Acids Research 50:21, pages 12291-12308.
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Thomas A. Wieser & Deborah S. Wuttke. (2022) Replication Protein A Utilizes Differential Engagement of Its DNA-Binding Domains to Bind Biologically Relevant ssDNAs in Diverse Binding Modes. Biochemistry 61:22, pages 2592-2606.
Crossref
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Yuxing Zhang, Lingling Yang, Kailun Fang, Qidan Li, Hongkai Xu, Yan Ren, Jin Zi, Charlie Degui Chen & Siqi Liu. (2022) Dynamic Responses of Chromosome-Binding Protein Complexes to Meiotic Prophase I of Mouse Spermatocyte. Journal of Proteome Research 21:11, pages 2715-2726.
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Simin Zhang, Xuejie Wang, Han Zhao, Jingyao Shi & Xuefeng Chen. (2022) New insights into the mechanism of RPA in preserving genome stability. Genome Instability & Disease 3:5, pages 255-266.
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Sahiti Kuppa, Jaigeeth Deveryshetty, Rahul Chadda, Jenna R. Mattice, Nilisha Pokhrel, Vikas Kaushik, Angela Patterson, Nalini Dhingra, Sushil Pangeni, Marisa K. Sadauskas, Sajad Shiekh, Hamza Balci, Taekjip Ha, Xiaolan Zhao, Brian Bothner & Edwin Antony. (2022) Rtt105 regulates RPA function by configurationally stapling the flexible domains. Nature Communications 13:1.
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Carlos E. Sanz-Rodríguez, Benjamin Hoffman, Paul J. Guyett, Andrei Purmal, Baljinder Singh, Michael P. Pollastri & Kojo Mensa-Wilmot. (2022) Physiologic Targets and Modes of Action for CBL0137, a Lead for Human African Trypanosomiasis Drug Development. Molecular Pharmacology 102:1, pages 1-16.
Crossref
Crossref
Kang Ning, Zekun Wang, Fang Cheng, Ziying Yan & Jianming Qiu. (2022) The small nonstructural protein NP1 of human bocavirus 1 directly interacts with Ku70 and RPA70 and facilitates viral DNA replication. PLOS Pathogens 18:6, pages e1010578.
Crossref
Crossref
Ping Zheng. (2022) Current understanding of genomic stability maintenancein pluripotent stem cells. Acta Biochimica et Biophysica Sinica 54:6, pages 858-863.
Crossref
Crossref
Silvia Hormeno, Oliver J. Wilkinson, Clara Aicart-Ramos, Sahiti Kuppa, Edwin Antony, Mark S. Dillingham & Fernando Moreno-Herrero. (2022) Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA. Proceedings of the National Academy of Sciences 119:15.
Crossref
Crossref
Richa SharmaSushree S. SahooMasayoshi Honda, Sophie L. GrangerCharnise Goodings, Louis SanchezAxel Künstner, Hauke Busch, Fabian BeierShondra M. Pruett-Miller, Marcus B. Valentine, Alfonso G. FernandezTi-Cheng ChangVincent Géli, Dmitri Churikov, Sandrine HirschiVictor B. PastorMelanie Boerries, Melchior Lauten, Charikleia KelaidiMegan A. Cooper, Sarah Nicholas, Jill A. Rosenfeld, Sophia Polychronopoulou, Caroline KannengiesserCarole Saintomé, Charlotte M. Niemeyer, Patrick Revy, Marc S. WoldMaria Spies, Miriam Erlacher, Stéphane Coulon & Marcin W. Wlodarski. (2022) Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue. Blood 139:7, pages 1039-1051.
Crossref
Crossref
Susan E. Tsutakawa, Albino Bacolla, Panagiotis Katsonis, Amer Bralić, Samir M. Hamdan, Olivier Lichtarge, John A. Tainer & Chi-Lin Tsai. (2021) Decoding Cancer Variants of Unknown Significance for Helicase–Nuclease–RPA Complexes Orchestrating DNA Repair During Transcription and Replication. Frontiers in Molecular Biosciences 8.
Crossref
Crossref
Logan R. Myler, Charles G. Kinzig, Nanda K. Sasi, George Zakusilo, Sarah W. Cai & Titia de Lange. (2021) The evolution of metazoan shelterin. Genes & Development 35:23-24, pages 1625-1641.
Crossref
Crossref
Riley M. Bednar, Subhashis Jana, Sahiti Kuppa, Rachel Franklin, Joseph Beckman, Edwin Antony, Richard B. Cooley & Ryan A. Mehl. (2021) Genetic Incorporation of Two Mutually Orthogonal Bioorthogonal Amino Acids That Enable Efficient Protein Dual-Labeling in Cells. ACS Chemical Biology 16:11, pages 2612-2622.
Crossref
Crossref
Ananya Acharya, Kristina Kasaciunaite, Martin Göse, Vera Kissling, Raphaël Guérois, Ralf Seidel & Petr Cejka. (2021) Distinct RPA domains promote recruitment and the helicase-nuclease activities of Dna2. Nature Communications 12:1.
Crossref
Crossref
Lin Wang, Jingzheng Li, Hu Zhou, Weidao Zhang, Jing Gao & Ping Zheng. (2021) A novel lncRNA Discn fine-tunes replication protein A (RPA) availability to promote genomic stability. Nature Communications 12:1.
Crossref
Crossref
Bidyut K Mohanty, Joseph AQ Karam, Breege V Howley, Annamarie C Dalton, Simon Grelet, Toros Dincman, William S Streitfeld, Je-Hyun Yoon, Lata Balakrishnan, Walter J Chazin, David T Long & Philip H Howe. (2021) Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrity. Life Science Alliance 4:9, pages e202000995.
Crossref
Crossref
Marilina Raices, Richard Bowman, Sarit Smolikove & Judith L. Yanowitz. (2021) Aging Negatively Impacts DNA Repair and Bivalent Formation in the C. elegans Germ Line. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Bilge Argunhan, Hiroshi Iwasaki & Hideo Tsubouchi. (2021) Post-translational modification of factors involved in homologous recombination. DNA Repair 104, pages 103114.
Crossref
Crossref
Joseph Tibbs, Mohamed Ghoneim, Colleen C Caldwell, Troy Buzynski, Wayne Bowie, Elizabeth M Boehm, M Todd Washington, S M Ali Tabei & Maria Spies. (2021) KERA: analysis tool for multi-process, multi-state single-molecule data. Nucleic Acids Research 49:9, pages e53-e53.
Crossref
Crossref
Bodil Kavli, Tobias S Iveland, Edith Buchinger, Lars Hagen, Nina B Liabakk, Per A Aas, Tobias S Obermann, Finn L Aachmann & Geir Slupphaug. (2021) RPA2 winged-helix domain facilitates UNG-mediated removal of uracil from ssDNA; implications for repair of mutagenic uracil at the replication fork. Nucleic Acids Research 49:7, pages 3948-3966.
Crossref
Crossref
Yinbo Zhang, Luther Davis & Nancy Maizels. (2021) Pathways and signatures of mutagenesis at targeted DNA nicks. PLOS Genetics 17:4, pages e1009329.
Crossref
Crossref
Barbara Stekas, Steve Yeo, Alice Troitskaia, Masayoshi Honda, Sei Sho, Maria Spies & Yann R Chemla. (2021) Switch-like control of helicase processivity by single-stranded DNA binding protein. eLife 10.
Crossref
Crossref
Adam Hefel, Masayoshi Honda, Nicholas Cronin, Kailey Harrell, Pooja Patel, Maria Spies & Sarit Smolikove. (2021)
RPA complexes in
Caenorhabditis elegans
meiosis; unique roles in replication, meiotic recombination and apoptosis
. Nucleic Acids Research 49:4, pages 2005-2026.
Crossref
Crossref
Faiz Ahmad, Angela Patterson, Jaigeeth Deveryshetty, Jenna R Mattice, Nilisha Pokhrel, Brian Bothner & Edwin Antony. (2021) Hydrogen–deuterium exchange reveals a dynamic DNA-binding map of replication protein A. Nucleic Acids Research 49:3, pages 1455-1469.
Crossref
Crossref
Tabitha Jenkins, Sarah J Northall, Denis Ptchelkine, Rebecca Lever, Andrew Cubbon, Hannah Betts, Vincenzo Taresco, Christopher D O Cooper, Peter J McHugh, Panos Soultanas & Edward L Bolt. (2021) The HelQ human DNA repair helicase utilizes a PWI-like domain for DNA loading through interaction with RPA, triggering DNA unwinding by the HelQ helicase core. NAR Cancer 3:1.
Crossref
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