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DNA Sequence Volume 15, 2004 - Issue 4
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Research Article

Cloning and Analysis of Human Apg16L

Huarui Zheng State Key Laboratory of Genetic Engineering Institute of Genetics, School of Life Sciences, Fudan University Shanghai 200433 People's Republic of China
,
Chaoneng Ji State Key Laboratory of Genetic Engineering Institute of Genetics, School of Life Sciences, Fudan University Shanghai 200433 People's Republic of China
,
Jixi Li State Key Laboratory of Genetic Engineering Institute of Genetics, School of Life Sciences, Fudan University Shanghai 200433 People's Republic of China
,
Hua Jiang State Key Laboratory of Genetic Engineering Institute of Genetics, School of Life Sciences, Fudan University Shanghai 200433 People's Republic of China
,
Mengru Ren State Key Laboratory of Genetic Engineering Institute of Genetics, School of Life Sciences, Fudan University Shanghai 200433 People's Republic of China
,
Qi Lu State Key Laboratory of Genetic Engineering Institute of Genetics, School of Life Sciences, Fudan University Shanghai 200433 People's Republic of China
,
Shaohua Gu State Key Laboratory of Genetic Engineering Institute of Genetics, School of Life Sciences, Fudan University Shanghai 200433 People's Republic of China
,
Yumin Mao State Key Laboratory of Genetic Engineering Institute of Genetics, School of Life Sciences, Fudan University Shanghai 200433 People's Republic of China
&
Yi Xie State Key Laboratory of Genetic Engineering Institute of Genetics, School of Life Sciences, Fudan University Shanghai 200433 People's Republic of China
 show all
Pages 303-305 | Published online: 11 Jul 2009

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Sonia Michail, Gilberto Bultron & R William DePaolo. (2013) Genetic variants associated with Crohn’s disease. The Application of Clinical Genetics 6, pages 25-32.
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Struan FA Grant, Robert N Baldassano & Hakon Hakonarson. (2008) Classification of genetic profiles of Crohn’s disease: a focus on the ATG16L1 gene. Expert Review of Molecular Diagnostics 8:2, pages 199-207.
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Articles from other publishers (20)

Wei Wang, Wenwen Yang, Jiejie Sun, Hongsheng Yao, Lingling Wang & Linsheng Song. (2023) A autophagy related-like protein 16-1 promotes the formation of autophagosomes and autolysosomes in antibacterial immune response of Pacific oyster Crassostrea gigas. Developmental & Comparative Immunology 147, pages 104748.
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Anne‐Sophie Hatat, Clara Benoit‐Pilven, Amélie Pucciarelli, Florence de Fraipont, Lucie Lamothe, Pascal Perron, Amandine Rey, Matteo Giaj Levra, Anne‐Claire Toffart, Didier Auboeuf, Beatrice Eymin & Sylvie Gazzeri. (2022) Altered splicing of ATG16‐L1 mediates acquired resistance to tyrosine kinase inhibitors of EGFR by blocking autophagy in non‐small cell lung cancer . Molecular Oncology 16:19, pages 3490-3508.
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Falan Han, Shuchao Pang, Zhaoqing Sun, Yinghua Cui & Bo Yan. (2021) Genetic Variants and Functional Analyses of the ATG16L1 Gene Promoter in Acute Myocardial Infarction. Frontiers in Genetics 12.
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Boon Pin Kee, Jin Guan Ng, Ching Ching Ng, Ida Hilmi, Khean Lee Goh & Kek Heng Chua. (2019) Genetic polymorphisms of ATG16L1 and IRGM genes in Malaysian patients with Crohn's disease . Journal of Digestive Diseases 21:1, pages 29-37.
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Abdolkarim Moazeni-Roodi, Farhad Tabasi, Saeid Ghavami & Mohammad Hashemi. (2019) Investigation of ATG16L1 rs2241880 Polymorphism with Cancer Risk: A Meta-Analysis. Medicina 55:8, pages 425.
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Qiuhong Xiong, Wenjing Li, Ping Li, Min Yang, Changxin Wu & Ludwig Eichinger. (2018) The Role of ATG16 in Autophagy and The Ubiquitin Proteasome System. Cells 8:1, pages 2.
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Juyi Wen, Hongliang Liu, Lili Wang, Xiaomeng Wang, Ning Gu, Zhensheng Liu, Ting Xu, Daniel R. Gomez, Ritsuko Komaki, Zhongxing Liao & Qingyi Wei. (2018) Potentially Functional Variants of ATG16L2 Predict Radiation Pneumonitis and Outcomes in Patients with Non–Small Cell Lung Cancer after Definitive Radiotherapy. Journal of Thoracic Oncology 13:5, pages 660-675.
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Lixia Wang, Jian Huang, Shuchao Pang, Xianyun Qin, Ziyou Qi, Robert G. Hawley & Bo Yan. (2017) Genetic analysis of the ATG16L1 gene promoter in sporadic Parkinson's disease. Neuroscience Letters 646, pages 30-35.
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Florin Burada, Marius Eugen Ciurea, Raluca Nicoli, Ioana Streata, Ionica Dan Vilcea, Ion Rogoveanu & Mihai Ioana. (2015) ATG16L1 T300A Polymorphism is Correlated with Gastric Cancer Susceptibility. Pathology & Oncology Research 22:2, pages 317-322.
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Kara G. LassenPetric KuballaKara L. ConwayKhushbu K. PatelChristine E. BeckerJoanna M. PeloquinEduardo J. VillablancaJason M. NormanTa-Chiang LiuRobert J. HeathMorgan L. BeckerLola FagbamiHeiko HornJohnathan MercerOmer H. YilmazJacob D. JaffeAlykhan F. ShamjiAtul K. BhanSteven A. CarrMark J. DalyHerbert W. Virgin, Stuart L. Schreiber, Thaddeus S. StappenbeckRamnik J. Xavier. (2014) Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense. Proceedings of the National Academy of Sciences 111:21, pages 7741-7746.
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Tao Jiang, Beibei Qin, Jianqin He, Shuangyan Lin & Shiping Ding. (2013) Three isoforms of the Atg16L1 protein contribute different autophagic properties. Molecular and Cellular Biochemistry 378:1-2, pages 257-266.
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Petric Kuballa, Whitney M. Nolte, Adam B. Castoreno & Ramnik J. Xavier. (2012) Autophagy and the Immune System. Annual Review of Immunology 30:1, pages 611-646.
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William G. Newman, Qing Zhang, Xiangdong Liu, Christopher I. Amos & Katherine A. Siminovitch. (2009) Genetic Variants in IL-23R and ATG16L1 Independently Predispose to Increased Susceptibility to Crohn's Disease in a Canadian Population. Journal of Clinical Gastroenterology 43:5, pages 444-447.
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Hitomi Nomura, Katsuhiro Uzawa, Yukio Yamano, Kazuaki Fushimi, Takashi Ishigami, Yukinao Kouzu, Hirofumi Koike, Masashi Siiba, Hiroki Bukawa, Hidetaka Yokoe, Hitoshi Kubosawa & Hideki Tanzawa. (2009) Overexpression and altered subcellular localization of autophagy-related 16-like 1 in human oral squamous-cell carcinoma: correlation with lymphovascular invasion and lymph-node metastasis. Human Pathology 40:1, pages 83-91.
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Petric Kuballa, Alan Huett, John D. Rioux, Mark J. Daly & Ramnik J. Xavier. (2008) Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant. PLoS ONE 3:10, pages e3391.
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Elizabeth V. Fowler, James Doecke, Lisa A. Simms, Zhen Zhen Zhao, Penelope M. Webb, Nicholas K. Hayward, David C. Whiteman, Timothy H. Florin, Grant W. Montgomery, Juleen A. Cavanaugh & Graham L. Radford-Smith. (2008) ATG16L1 T300A Shows Strong Associations With Disease Subgroups in a Large Australian IBD Population: Further Support for Significant Disease Heterogeneity. The American Journal of Gastroenterology 103:10, pages 2519-2526.
Crossref
Hernán O. Ghiglione, Fernanda G. Gonzalez, Román Serrago, Sara B. Maldonado, Charles Chilcott, José A. Curá, Daniel J. Miralles, Tong Zhu & Jorge J. Casal. (2008) Autophagy regulated by day length determines the number of fertile florets in wheat. The Plant Journal 55:6, pages 1010-1024.
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Rinse K. Weersma, Alexandra Zhernakova, Ilja M. Nolte, Céline Lefebvre, John D. Rioux, Flip Mulder, Hendrik M. van Dullemen, Jan H. Kleibeuker, Cisca Wijmenga & Gerard Dijkstra. (2008) ATG16L1 and IL23R Are Associated With Inflammatory Bowel Diseases but Not With Celiac Disease in The Netherlands . The American Journal of Gastroenterology 103:3, pages 621-627.
Crossref
Rebecca L. Roberts, Richard B. Gearry, Jade E. Hollis-Moffatt, Allison L. Miller, Julia Reid, Victor Abkevich, Kirsten M. Timms, Alexander Gutin, Jerry S. Lanchbury, Tony R. Merriman, Murray L. Barclay & Martin A. Kennedy. (2007) IL23R R381Q and ATG16L1 T300A Are Strongly Associated With Crohn's Disease in a Study of New Zealand Caucasians With Inflammatory Bowel Disease. The American Journal of Gastroenterology 102:12, pages 2754-2761.
Crossref
Jochen Hampe, Andre Franke, Philip Rosenstiel, Andreas Till, Markus Teuber, Klaus Huse, Mario Albrecht, Gabriele Mayr, Francisco M De La Vega, Jason Briggs, Simone Günther, Natalie J Prescott, Clive M Onnie, Robert Häsler, Bence Sipos, Ulrich R Fölsch, Thomas Lengauer, Matthias Platzer, Christopher G Mathew, Michael Krawczak & Stefan Schreiber. (2006) A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nature Genetics 39:2, pages 207-211.
Crossref

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