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Original Articles

Synthesis, Reactions, and Antiviral Activity of 6′-Amino-2′-thioxo-1′,2′-dihydro-3,4′-bipyridine-3′,5′-dicarbonitrile

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Pages 695-709 | Received 04 Jan 2006, Accepted 14 Mar 2006, Published online: 24 Feb 2007

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Read on this site (9)

AzzaM. Abdel-Fattah & FawzyA. Attaby. (2012) Synthesis, Reactions, and Characterization of 6-Amino-4-(Benzo[b]Thiophen-2-YL)-2-Thioxo-1, 2-Dihydropyridine-3, 5-Dicarbonitrile. Phosphorus, Sulfur, and Silicon and the Related Elements 187:5, pages 555-563.
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Fawzy A. Attaby, Ahmed H. El-Ghandour, Abdelwahed R. Sayed, Ashraf A. El Bassuony & AhmedA.M. El-Reedy. (2012) Synthesis and characterization of 6-(aryl)-2-thioxo-1,2-dihydropyridine-3-carbonitriles. Journal of Sulfur Chemistry 33:2, pages 197-221.
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FawzyA. Attaby, AzzaM. Abdel-Fattah, LabeebM. Shaif & MohamedM. Elsayed. (2010) Anti-Alzheimer and Anti-COX-2 Activities of the Newly Synthesized 2,3′-Bipyridine Derivatives (II). Phosphorus, Sulfur, and Silicon and the Related Elements 185:3, pages 668-679.
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FawzyA. Attaby, AzzaM. Abdel-Fattah, LabeebM. Shaif & MohamedM. Elsayed. (2009) Anti-Alzheimer and Anti-Cox-2 Activities of the Newly Synthesized 2,3′-Bipyridine Derivatives (I). Phosphorus, Sulfur, and Silicon and the Related Elements 185:1, pages 129-139.
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Abdel Haleem M. Hussein, MohamedA. M. Gad-Elkareem, Abu-BakrA. A. M. El-Adasy & IsmailM. Othman. (2009) N-1-Naphthyl-3-oxobutanamide in Heterocyclic Synthesis: A Facile Synthesis of Nicotinamide, Thieno[2,3-b]pyridine, and Bi- or Tricyclic Annulated Pyridine Derivatives Containing Naphthyl Moiety. Phosphorus, Sulfur, and Silicon and the Related Elements 184:9, pages 2263-2280.
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AzzaM. Abdel-Fattah, LabeebM. Shaif & FawzyA. Attaby. (2008) Synthesis of Heterocycles via 2-Thioxo-1,2-dihydropyridine-3-carbonitrile Derivative. Phosphorus, Sulfur, and Silicon and the Related Elements 183:10, pages 2443-2456.
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A.M. Abdel-Fattah, M.A. A. Elneairy, M.N. Gouda & F.A. Attaby. (2008) Synthesis, Characterization, and Reactions of Pyridine-3-Carbonitrile Derivatives. Phosphorus, Sulfur, and Silicon and the Related Elements 183:7, pages 1592-1614.
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Articles from other publishers (13)

Daniela Catarzi, Flavia Varano, Erica Vigiani, Sara Calenda, Fabrizio Melani, Katia Varani, Fabrizio Vincenzi, Silvia Pasquini, Natascia Mennini, Giulia Nerli, Diego Dal Ben, Rosaria Volpini & Vittoria Colotta. (2022) 4-Heteroaryl Substituted Amino-3,5-Dicyanopyridines as New Adenosine Receptor Ligands: Novel Insights on Structure-Activity Relationships and Perspectives. Pharmaceuticals 15:4, pages 478.
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O. F. Ibrahim, E. A. Bakhite, S. A. M. Metwally, Y. A. El-Ossaily, H. H. M. Abdu-Allah, E. A. Al-Taifi & M. Kandel. (2021) Synthesis, Characterization, and Antifungal Activity of Some New Thieno[2,3-b]pyridines Incorporating Quinazoline or Benzimidazole Moiety. Russian Journal of Bioorganic Chemistry 47:4, pages 918-928.
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I. N. Bardasov, A. Yu. Alekseeva, D. L. Mikhailov, А. I. Ershova & O. V. Ershov. (2020) Synthesis of 4-Amino-6-aryl-2-sulfanylpyridine-3,5-dicarbonitriles. Russian Journal of Organic Chemistry 56:8, pages 1491-1494.
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Ya. S. Kayukov, S. V. Karpov, O. V. Kayukova & A. A. Grigor’ev. (2020) Synthesis of 4-Acyl-2-amino-6-(arylsulfanyl)pyridine-3,5-dicarbonitriles. Russian Journal of Organic Chemistry 56:7, pages 1313-1316.
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Safiyyah A. H. Al‐Waleedy, Etify A. Bakhite, Mohamed S. Abbady & Hajjaj H. M. Abdu‐Allah. (2020) Synthesis and characterization of some new pyridines, thieno[2,3‐ b ] pyridines and pyrido[3′,2′:4,5]thieno[3,2‐ d ]pyrimidine‐4(3 H )‐ones bearing styryl moiety . Journal of Heterocyclic Chemistry 57:6, pages 2379-2388.
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Marco Betti, Daniela Catarzi, Flavia Varano, Matteo Falsini, Katia Varani, Fabrizio Vincenzi, Silvia Pasquini, Lorenzo di Cesare Mannelli, Carla Ghelardini, Elena Lucarini, Diego Dal Ben, Andrea Spinaci, Gianluca Bartolucci, Marta Menicatti & Vittoria Colotta. (2019) Modifications on the Amino-3,5-dicyanopyridine Core To Obtain Multifaceted Adenosine Receptor Ligands with Antineuropathic Activity. Journal of Medicinal Chemistry 62:15, pages 6894-6912.
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Vladimir D. Dyachenko, Ivan V. Dyachenko & Valentine G. Nenajdenko. (2018) Cyanothioacetamide: a polyfunctional reagent with broad synthetic utility. Russian Chemical Reviews 87:1, pages 1-27.
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Etify A. Bakhite, Joel T. Mague, Mehmet Akkurt, Shaaban K. Mohamed & Elham A. Al-Taifi. (2017) Ethyl 3-amino-2-cyano-4-(4-methoxyphenyl)-6- methylthieno[2,3- b ]pyridine-5-carboxylate . IUCrData 2:11.
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H. Abdel-Ghany, A. M. El-Sayed, A. A. Amer & A. M. Ahmed. (2016) Synthesis of Novel Fused Heterocycles Based on 6-Amino-4-phenyl-2-thioxo-1,2-dihydropyridine-3,5-dicarbonitrile. Journal of Heterocyclic Chemistry 53:6, pages 2013-2019.
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Etify A. Bakhite, Manpreet Kaur, Shaaban K. Mohamed, Mehmet Akkurt, Jerry P. Jasinski & Mustafa R. Albayati. (2016) Ethyl 3-amino-2-carbamoyl-4-(4-methoxyphenyl)-6-methylthieno[2,3- b ]pyridine-5-carboxylate dimethyl sulfoxide monosolvate . IUCrData 1:9.
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Etify A. Bakhite, Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt & Elham A. Al-Taifi. (2016) Ethyl 3-amino-4-(4-chlorophenyl)-2-[(4-methoxyphenyl)carbamoyl]-6-phenylthieno[2,3- b ]pyridine-5-carboxylate . IUCrData 1:4.
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Ahmed A. M. Elreedy, Hameed M. Alkubaisi & Fawzy A. Attaby. (2016) Synthesis, Reactions and Characterization of 1,1’-(1,4-Phenylenebis(3-amino-6-methyl-1H-pyrazolo[3,4-b]pyridine-4,5-diyl))bis(ethan-1-one). International Journal of Organic Chemistry 06:01, pages 65-76.
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Fawzy A. Attaby, Azza M. Abdel-Fattah, Labeeb M. Shaif & Mohamed M. Elsayed. (2014) Synthesis, Reactions, Characterization and Biological Evaluation of 2,3′-Bipyridine Derivatives (III). Journal of Heterocyclic Chemistry 51:4, pages 927-936.
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