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Original Articles

Synthesis of Some New 1,2,3,4-Tetrahydropyrimidine-2- thiones and Their Thiazolo[3,2-a]pyrimidine Derivatives as Potential Biological Agents

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Pages 1911-1922 | Received 03 Aug 2007, Accepted 01 Sep 2007, Published online: 28 Jul 2008

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Nitin Rode, Aafaq Tantray, Amruta Shelar, Rajendra Patil & Santosh Terdale. (2022) Amino acid ionic liquid-catalyzed synthesis, anti-Leishmania activity, molecular docking, molecular dynamic simulation, and ADME study of 3,4-dihydropyrimidin-2(1H)-(thio)ones. Synthetic Communications 52:2, pages 190-204.
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Articles from other publishers (16)

Marwa Mostafa Moharam, Ebraheem Abdu Musad Saleh, Ismail Hassan & Kakul Husain. (2023) Synthesis, Antifungal, and Antioxidant Evaluation of New Class of Thiazolo[3,2-a]pyrimidine and Pyrimido[5,4-d]thiazolo[3,2-a]pyrimidine Derived from α,α-Ketene Dithioacetals as Five and Six-membered Heterocycles Analogues. Russian Journal of Bioorganic Chemistry 49:5, pages 1119-1136.
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Jaysinh Jadeja & Mahesh Savant. (2023) Synthesis of thiazolo[3,2-a]pyrimidine molecules, in vitro cytotoxic evaluation and molecular docking studies. Journal of the Iranian Chemical Society 20:7, pages 1491-1502.
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Sasadhar Majhi & Ipsita Saha. (2022) Visible Light-promoted Synthesis of Bioactive N, N-heterocycles. Current Green Chemistry 9:3, pages 127-144.
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Ramakanth Pagadala, Venkatesan Kasi, Nhlanhla Gracious Shabalala & Sreekantha B. Jonnalagadda. (2022) Ultrasound-assisted multicomponent synthesis of heterocycles in water – A review. Arabian Journal of Chemistry 15:1, pages 103544.
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Ranjana Aggarwal, Naman Jain, Shilpa Sharma, Prince Kumar, Gyan Prakash Dubey, Heerak Chugh & Ramesh Chandra. (2021) Visible-light driven regioselective synthesis, characterization and binding studies of 2-aroyl-3-methyl-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidines with DNA and BSA using biophysical and computational techniques. Scientific Reports 11:1.
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Mayur S. BhosaleK. SarvananN. S. Dighe. (2021) Recent Progress on Synthesis and Bio-activities of Tetrahydropyrimidine-2-one derivatives. Research Journal of Science and Technology, pages 221-228.
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Hayat E. Alzahrani, Ahmed M. Fouda & Ayman M. S. Youssef. (2019) Selective cyclization of S‐substituted pyrimidinethione: Synthesis and antimicrobial evaluation of novel polysubstituted thiazolopyrimidine and thiazolodipyrimidine derivatives. Journal of the Chinese Chemical Society 67:5, pages 838-855.
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Priyanka Dhiman, Neelam Malik, Prabhakar K. Verma & Anurag Khatkar. (2015) Synthesis and biological evaluation of thiazolo and imidazo N-(4-nitrophenyl)-7-methyl-5-aryl-pyrimidine-6 carboxamide derivatives. Research on Chemical Intermediates 41:11, pages 8699-8711.
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Neelam Malik, Priyanka Dhiman, Prabhakar K. Verma & Anurag Khatkar. (2014) Design, synthesis, and biological evaluation of thiourea and guanidine derivatives of pyrimidine-6-carboxylate. Research on Chemical Intermediates 41:10, pages 7981-7993.
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María A. Schiel, Alicia B. Chopa, Gustavo F. Silbestri, Mónica B. Alvarez, Adriana G. Lista & Claudia E. Domini. 2015. Green Synthetic Approaches for Biologically Relevant Heterocycles. Green Synthetic Approaches for Biologically Relevant Heterocycles 571 601 .
K. Venkatesan, V. S. V. Satyanarayana & A. Sivakumar. (2014) Ultrasound‐Assisted Synthesis of 6‐Methyl‐1,2,3,4‐tetrahydro‐ N ‐aryl‐2‐oxo/thio‐4‐arylpyrimidine‐5‐carboxamides Catalyzed by Uranyl Nitrate Hexahydrate . Journal of the Chinese Chemical Society 61:6, pages 624-630.
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Vinita Sharma, Nitin Chitranshi & Ajay Kumar Agarwal. (2014) Significance and Biological Importance of Pyrimidine in the Microbial World. International Journal of Medicinal Chemistry 2014, pages 1-31.
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Ramakanth Pagadala, Suresh Maddila & Sreekantha B. Jonnalagadda. (2014) Eco-efficient ultrasonic responsive synthesis of pyrimidines/pyridines. Ultrasonics Sonochemistry 21:2, pages 472-477.
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Kawaljit Singh & Kamaljit Singh. 2012. 223 308 .
Nimesh R. Kamdar, Dhaval D. Haveliwala, Prashant T. Mistry & Saurabh K. Patel. (2010) Design, synthesis and in vitro evaluation of antitubercular and antimicrobial activity of some novel pyranopyrimidines. European Journal of Medicinal Chemistry 45:11, pages 5056-5063.
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Maksim A. Kolosov, Valeriy D. Orlov, Dmitriy A. Beloborodov & Victor V. Dotsenko. (2008) A chemical placebo: NaCl as an effective, cheapest, non-acidic and greener catalyst for Biginelli-type 3,4-dihydropyrimidin-2(1H)-ones (-thiones) synthesis. Molecular Diversity 13:1, pages 5-25.
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