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Phosphorus, Sulfur, and Silicon and the Related Elements Volume 186, 2011 - Issue 4: 18th International Conference on Phosphorus Chemistry (ICPC2010)
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IV. Biologically Relevant Organophosphorus Compounds

Synthesis and Characterization of Novel Fluorescent Nitrogen-Containing Bisphosphonate Imaging Probes for Bone Active Drugs

Shuting Sun Department of Chemistry, University of Southern California, Los Angeles, California, USA
,
Katarzyna M. Błażewska Department of Chemistry, University of Southern California, Los Angeles, California, USA; Institute of Organic Chemistry, Technical University of Łódź, Łódź, Poland
,
Boris A. Kashemirov Department of Chemistry, University of Southern California, Los Angeles, California, USA
,
Anke J. Roelofs Bone & Musculoskeletal Research Programme, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK
,
Fraser P. Coxon Bone & Musculoskeletal Research Programme, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK
,
Michael J. Rogers Bone & Musculoskeletal Research Programme, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK
,
Frank H. Ebetino Warner Chilcott Pharmaceuticals, Cincinnati, Ohio, USA
,
Michael J. McKenna Harvard Medical School and Massachusetts Eye & Ear Infirmary, Boston, Massachusetts, USA
&
Charles E. McKenna Department of Chemistry, University of Southern California, Los Angeles, California, USA
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Pages 970-971 | Received 15 Sep 2010, Accepted 21 Sep 2010, Published online: 25 Apr 2011

Citations (15)

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Read on this site (1)

Shuting Sun & Charles E McKenna. (2011) Farnesyl pyrophosphate synthase modulators: a patent review (2006 – 2010). Expert Opinion on Therapeutic Patents 21:9, pages 1433-1451.
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Articles from other publishers (14)

Eric T. Richard, Kenzo Morinaga, Yiying Zheng, Oskar Sundberg, Akishige Hokugo, Kimberly Hui, Yipin Zhou, Hodaka Sasaki, Boris A. Kashemirov, Ichiro Nishimura & Charles E. McKenna. (2021) Design and Synthesis of Cathepsin-K-Activated Osteoadsorptive Fluorogenic Sentinel (OFS) Probes for Detecting Early Osteoclastic Bone Resorption in a Multiple Myeloma Mouse Model. Bioconjugate Chemistry 32:5, pages 916-927.
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Vadim D. Romanenko. (2019) α-Heteroatom-substituted gem-Bisphosphonates: Advances in the Synthesis and Prospects for Biomedical Application. Current Organic Chemistry 23:5, pages 530-615.
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Andrea Chiminazzo, Giuseppe Borsato, Alessia Favero, Chiara Fabbro, Charles E. McKenna, Luca Giuseppe Dalle Carbonare, Maria Teresa Valenti, Fabrizio Fabris & Alessandro Scarso. (2019) Diketopyrrolopyrrole Bis‐Phosphonate Conjugate: A New Fluorescent Probe for In Vitro Bone Imaging. Chemistry – A European Journal 25:14, pages 3617-3626.
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I. Qayoom, D. B. Raina, A. Širka, Š. Tarasevičius, M. Tägil, A. Kumar & L. Lidgren. (2018) Anabolic and antiresorptive actions of locally delivered bisphosphonates for bone repair. Bone & Joint Research 7:10, pages 548-560.
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Woo Seok Kang, Kim Nguyen, Charles E. McKenna, William F. Sewell, Michael J. McKenna & David H. Jung. (2016) Measurement of Ototoxicity Following Intracochlear Bisphosphonate Delivery. Otology & Neurotology 37:6, pages 621-626.
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Woo Seok Kang, Kim Nguyen, Charles E. McKenna, William F. Sewell, Michael J. McKenna & David H. Jung. (2016) Intracochlear Drug Delivery Through the Oval Window in Fresh Cadaveric Human Temporal Bones. Otology & Neurotology 37:3, pages 218-222.
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Woo Seok Kang, Shuting Sun, Kim Nguyen, Boris Kashemirov, Charles E. McKenna, S. Adam Hacking, Alicia M. Quesnel, William F. Sewell, Michael J. McKenna & David H. Jung. (2015) Non-Ototoxic Local Delivery of Bisphosphonate to the Mammalian Cochlea. Otology & Neurotology 36:6, pages 953-960.
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Ciara M Murphy, Aaron Schindeler, Laurence C Cantrill, Kathy Mikulec, Lauren Peacock & David G Little. (2015) PTH (1-34) Treatment Increases Bisphosphonate Turnover in Fracture Repair in Rats . Journal of Bone and Mineral Research 30:6, pages 1022-1029.
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Anja Verhulst, Shuting Sun, Charles E. McKenna & Patrick C. D’Haese. (2015) Endocytotic Uptake of Zoledronic Acid by Tubular Cells May Explain Its Renal Effects in Cancer Patients Receiving High Doses of the Compound. PLOS ONE 10:3, pages e0121861.
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Simon Cheong, Shuting Sun, Benjamin Kang, Olga Bezouglaia, David Elashoff, Charles E. McKenna, Tara L. Aghaloo & Sotirios Tetradis. (2014) Bisphosphonate Uptake in Areas of Tooth Extraction or Periapical Disease. Journal of Oral and Maxillofacial Surgery 72:12, pages 2461-2468.
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SUSAN BAE, SHUTING SUN, TARA AGHALOO, JU-EUN OH, CHARLES E. McKENNA, MO K. KANG, KI-HYUK SHIN, SOTIRIOS TETRADIS, NO-HEE PARK & REUBEN H. KIM. (2014) Development of oral osteomucosal tissue constructs in vitro and localization of fluorescently-labeled bisphosphonates to hard and soft tissue. International Journal of Molecular Medicine 34:2, pages 559-563.
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Akishige Hokugo, Shuting Sun, Sil Park, Charles E. McKenna & Ichiro Nishimura. (2013) Equilibrium-dependent bisphosphonate interaction with crystalline bone mineral explains anti-resorptive pharmacokinetics and prevalence of osteonecrosis of the jaw in rats. Bone 53:1, pages 59-68.
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John Turek, F. Hal Ebetino, Mark W. Lundy, Shuting Sun, Boris A. Kashemirov, Charles E. McKenna, Maxime A. Gallant, Lilian I. Plotkin, Teresita Bellido, Xuchen Duan, James T. Triffitt, R. Graham G. Russell, David B. Burr & Matthew R. Allen. (2012) Bisphosphonate Binding Affinity Affects Drug Distribution in Both Intracortical and Trabecular Bone of Rabbits. Calcified Tissue International 90:3, pages 202-210.
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Frank H. Ebetino, Anne-Marie L. Hogan, Shuting Sun, Maria K. Tsoumpra, Xuchen Duan, James T. Triffitt, Aaron A. Kwaasi, James E. Dunford, Bobby L. Barnett, Udo Oppermann, Mark W. Lundy, Alan Boyde, Boris A. Kashemirov, Charles E. McKenna & R. Graham G. Russell. (2011) The relationship between the chemistry and biological activity of the bisphosphonates. Bone 49:1, pages 20-33.
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