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Original Articles

Synthesis of Polyfunctionally Substituted Thiophene, Thieno[2,3-b]pyridine and Thieno[2,3-d]pyrimidine Derivatives

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Pages 1815-1827 | Received 06 Jun 2004, Accepted 07 Sep 2004, Published online: 18 Aug 2006

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Natalia A. Larionova, Anatoliy M. Shestopalov, Lyudmila A. Rodinovskaya & Andrey A. Zubarev. (2021) Synthesis of Biologically Active Heterocycles via a Domino Sequence Involving an SN2/Thorpe–Ziegler Reaction Step. Synthesis 54:02, pages 217-245.
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Ram W. Sabnis. (2016) The Gewald reaction in dye chemistry. Coloration Technology 132:1, pages 49-82.
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Reza Tayebee, S. Javad Ahmadi, Esmaeil Rezaei Seresht, Farzad Javadi, Mohammad A. Yasemi, Morteza Hosseinpour & Behrouz Maleki. (2012) Commercial Zinc Oxide: A Facile, Efficient, and Eco-friendly Catalyst for the One-Pot Three-Component Synthesis of Multisubstituted 2-Aminothiophenes via the Gewald Reaction. Industrial & Engineering Chemistry Research 51:44, pages 14577-14582.
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Wagnat W. Wardakhan, Sherif M. Sherif, Rafat M. Mohareb & Amr S. Abouzied. (2012) The Reaction of Cyanoacetylhdrazine with Furan-2-Aldehyde: Novel Synthesis of Thiophene, Azole, Azine and Coumarin Derivatives and Their Antitumor Evaluation. International Journal of Organic Chemistry 02:04, pages 321-331.
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Xian-Gui Huang, Jia Liu, Jiangmeng Ren, Tao Wang, Weidong Chen & Bu-Bing Zeng. (2011) A facile and practical one-pot synthesis of multisubstituted 2-aminothiophenes via imidazole-catalyzed Gewald reaction. Tetrahedron 67:34, pages 6202-6205.
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Hoda Z. Shams, Rafat M. Mohareb, Maher H. Helal & Amira E. Mahmoud. (2010) Novel Synthesis and Antitumor Evaluation of Polyfunctionally Substituted Heterocyclic Compounds Derived from 2-Cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-acetamide. Molecules 16:1, pages 52-73.
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Wagnat Wardakhan, Omar Abdel-Salam & Gamal Elmegeed. (2008) Screening for antidepressant, sedative and analgesic activities of novel fused thiophene derivatives. Acta Pharmaceutica 58:1, pages 1-14.
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J. Schatz, T. Brendgen & D. Schühle. 2008. Comprehensive Heterocyclic Chemistry III. Comprehensive Heterocyclic Chemistry III 931 974 .
Wagnat W. Wardakhan. (2006) Novel Synthesis of 1,3,4‐Thiadiazine Derivatives and Their Cycloaddition Reactions. Archiv der Pharmazie 339:11, pages 608-615.
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Wagnat W. Wardakhan, Hoda Z. Shams & Hosam E. Moustafa. (2005) Synthesis of Polyfunctionally Substituted Thiophene, Thieno[2,3‐b]pyridine and Thieno[2,3‐d]pyrimidine Derivatives.. ChemInform 36:45.
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