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Original Articles

SYNTHETIC POTENTIALITIES OF THIOPHENE SYSTEMS IN HETEROCYCLIC SYNTHESIS: A NOVEL SYNTHESIS OF THIENO[2,3-b]PYRIDINE DERIVATIVES

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Pages 215-233 | Received 10 Mar 1999, Accepted 04 May 1999, Published online: 04 Oct 2006

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Ghazala Khanum, Aysha Fatima, Rafiq Ahmad Rather, Nazia Siddiqui, Sambanthan Muthu, Sanjay Kumar Srivastava & Saleem Javed. (2023) Synthesis, Spectroscopic, Quantum Chemical, and Molecular Docking Studies of 2-Cyano-N-Cyclopropylacetamide and 2-Cyano-N-(1-Phenylethyl)Acetamide. Polycyclic Aromatic Compounds 43:10, pages 9047-9073.
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Wagnat W. Wardakhan, Hoda Z. Shams & Hosam E. Moustafa. (2005) Synthesis of Polyfunctionally Substituted Thiophene, Thieno[2,3-b]pyridine and Thieno[2,3-d]pyrimidine Derivatives. Phosphorus, Sulfur, and Silicon and the Related Elements 180:8, pages 1815-1827.
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Siham Lahsasni, Dunya A. M. Al-Hemyari, Hazem A. Ghabbour, Yahia Nasser Mabkhoot, Fadilah S. Aleanizy, Asma A. Alothman & Zainab M. Almarhoon. (2018) Synthesis, Characterization, and Antibacterial and Anti-Inflammatory Activities of New Pyrimidine and Thiophene Derivatives. Journal of Chemistry 2018, pages 1-11.
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Rafat M. Mohareb, Fatima Al-Omran & Rehab A. Ibrahim. (2017) The uses of cyclohexan-1,4-dione for the synthesis of thiophene derivatives as new anti-proliferative, prostate anticancer, c-Met and tyrosine kinase inhibitors. Medicinal Chemistry Research 27:2, pages 618-633.
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Mohamed A. Raslan, Samia M. Sayed & Mohamed A. Khalil. (2016) Synthesis of Some Pyrazole, Thiazole, Pyridine, and 1,3,4-Thiadiazole Derivatives Incorporating 2-Thiazolyl Moiety. Journal of Heterocyclic Chemistry 53:3, pages 727-733.
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Ahmed A. Fadda & Ramy Rabie. (2015) Cyanoacetylation of amines: recent advances in preparation methods and their synthetic uses in the formation of biologically active compounds. Research on Chemical Intermediates 42:2, pages 771-811.
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Abdul Rauf, Khalil Ahmed Nazish, Faiz-ul Hassan Nasim, Asma Yaqoob & Ashfaq Mahmood Qureshi. (2015) Synthesis of novel cyanoacetamides derivatives and their urease inhibition studies. European Journal of Chemistry 6:2, pages 163-168.
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Hoda Z. Shams, Rafat M. Mohareb, Maher H. Helal & Amira E. Mahmoud. (2010) Novel Synthesis and Antitumor Evaluation of Polyfunctionally Substituted Heterocyclic Compounds Derived from 2-Cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-acetamide. Molecules 16:1, pages 52-73.
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V. D. Dyachenko, R. P. Tkachiov & O. S. Bityukova. (2008) Chemical properties of cyanoacetanilides and synthesis of biologically active compounds around them. Russian Journal of Organic Chemistry 44:11, pages 1565-1579.
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Agnieszka Miszke, Henryk Foks, Anna Kedzia, Ewa Kwapisz & Zofia Zwolska. (2008) The Synthesis and Microbiological Activity of 2-Mercapto-4-(pyrrolidin-1-yl)pyridine-3-carbonitrile Derivatives. HETEROCYCLES 75:9, pages 2251.
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V. D. Dyachenko. (2005) Cyclohexene-4-carbaldehyde in the Synthesis of 4-(Cyclohex-3-enyl)-Substituted 4H-Chromenes, 4H-Thiopyrans, 1,4,5,6,7,8-Hexahydroquinolines, 1,4-Dihydropyridines, Pyridines, and 6,7-Dihydro-5H-[1]pyrindines. Russian Journal of General Chemistry 75:10, pages 1537-1544.
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