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Original Articles

The Discovery of the Bone-Active Agent Risedronate, and Bisphosphonate Structure-Activity Considerations Including the Aminophenylethane Phosphonate Series

Pages 9-12 | Published online: 17 Mar 2008

Keep up to date with the latest research on this topic with citation updates for this article.

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HarryR. Hudson, RosalindJ. Lee & RayW. Matthews. (2004) 1-AMINO-1-ARYL- AND 1-AMINO-1-HETEROARYL-METHANEPHOSPHONIC ACIDS AND THEIR N-BENZHYDRYL–PROTECTED DIETHYL ESTERS: PREPARATION AND CHARACTERIZATION. Phosphorus, Sulfur, and Silicon and the Related Elements 179:9, pages 1691-1709.
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Articles from other publishers (31)

Andrey A. Prishchenko, Roman S. Alekseyev, Olga P. Novikova, Mikhail V. Livantsov, Ludmila I. Livantsova & Valery S. Petrosyan. (2022) Catalytic N-diphosphonomethylation of amino alkanols and bisamino alkanes using tris(trimethylsilyl) phosphite as a convenient synthon. Journal of Organometallic Chemistry 957, pages 122143.
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Michael R. McClung & Frank H. Ebetino. (2020) History of risedronate. Bone 137, pages 115407.
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Andrey A. Prishchenko, Roman S. Alekseyev, Mikhail V. Livantsov, Olga P. Novikova, Ludmila I. Livantsova & Valery S. Petrosyan. (2020) Silicon-assisted synthesis of new aminomethylenebisphosphonic acids with quinolines moieties. Journal of Organometallic Chemistry 917, pages 121286.
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Andrey A. Prishchenko, Roman S. Alekseyev, Mikhail V. Livantsov, Olga P. Novikova, Ludmila I. Livantsova & Valery S. Petrosyan. (2020) Synthesis of new functionalized aryl and pyridyl aminomethylenebisphosphonic acids and their derivatives via silicon-assisted methodology. Journal of Organometallic Chemistry 912, pages 121177.
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Andrey A. Prishchenko, Roman S. Alekseyev, Mikhail V. Livantsov, Olga P. Novikova, Ludmila I. Livantsova & Valery S. Petrosyan. (2018) Organosilicon based synthesis of new functionalized aminomethylenediphosphonates with moieties of amino acids. Journal of Organometallic Chemistry 871, pages 36-39.
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Andrey A. Prishchenko, Roman S. Alekseyev, Mikhail V. Livantsov, Olga P. Novikova, Ludmila I. Livantsova & Valery S. Petrosyan. (2018) Tris(trimethylsilyl) phosphite as key synthon for convenient synthesis of new organosilicon(phosphorus)-containing N-heterocycles. Journal of Organometallic Chemistry 867, pages 149-154.
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Andrey A. Prishchenko, Mikhail V. Livantsov, Olga P. Novikova, Ludmila I. Livantsova & Valery S. Petrosyan. (2018) Synthesis of new functionalized hydroxy- and aminomethylphosphinates with indan moieties. Heteroatom Chemistry 29:2, pages e21419.
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Joanna Gałęzowska. (2018) Interactions between Clinically Used Bisphosphonates and Bone Mineral: from Coordination Chemistry to Biomedical Applications and Beyond. ChemMedChem 13:4, pages 289-302.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova, L. I. Livantsova & V. S. Petrosyan. (2016) Synthesis of (aminomethylene)bisphosphonic acid derivatives. Russian Chemical Bulletin 65:1, pages 228-232.
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Anna Kuźnik, Roman Mazurkiewicz, Mirosława Grymel, Katarzyna Zielińska, Jakub Adamek, Ewa Chmielewska, Marta Bochno & Sonia Kubica. (2015) A new method for the synthesis of α-aminoalkylidenebisphosphonates and their asymmetric phosphonyl-phosphinyl and phosphonyl-phosphinoyl analogues. Beilstein Journal of Organic Chemistry 11, pages 1418-1424.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova, L. I. Livantsova, I. S. Ershov & V. S. Petrosyan. (2015) Synthesis of new types of aminomethylenediphosphorus-containing acids and their derivatives. Russian Journal of General Chemistry 85:2, pages 370-379.
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Yuliya V. Rassukana, Ivanna P. Yelenich, Anatoly D. Synytsya & Petro P. Onys'ko. (2014) Fluorinated NH-iminophosphonates and iminocarboxylates: novel synthons for the preparation of biorelevant α-aminophosphonates and carboxylates. Tetrahedron 70:18, pages 2928-2937.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova, L. I. Livantsova, I. S. Ershov & V. S. Petrosyan. (2014) Reaction of Bis(trimethylsiloxy)phosphine with ethoxymethyleneimines hydrochlorides. Russian Journal of General Chemistry 84:3, pages 605-607.
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Andrey A. Prishchenko, Mikhail V. Livantsov, Olga P. Novikova, Ludmila I. Livantsova, Ivan S. Ershov & Valery S. Petrosyan. (2013) Synthesis and Reactivity of the New Trimethylsilyl Esters of Aminomethylenebisorganophosphorus Acids. Heteroatom Chemistry 24:5, pages 355-360.
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Andrey A. Prishchenko, Mikhail V. Livantsov, Olga P. Novikova, Ludmila I. Livantsova & Valery S. Petrosyan. (2013) Synthesis of New Heterocyclic Mono- and Bisorganophosphorus Acids and Their Derivatives with 1,2-Phenylene Fragments. Heteroatom Chemistry 24:4, pages 332-335.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova, L. I. Livantsova, I. S. Ershov & V. S. Petrosyan. (2013) Synthesis of N-substituted aminomethylenediphosphonites and their derivatives. Russian Journal of General Chemistry 83:6, pages 1175-1177.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova, L. I. Livantsova, I. S. Ershov & V. S. Petrosyan. (2012) Synthesis of N,N-disubstituted aminomethylenediphosphonates and their derivatives. Russian Journal of General Chemistry 82:9, pages 1593-1595.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova & L. I. Livantsova. (2011) Synthesis of unsaturated α-ketophosphonates and their derivatives. Russian Journal of General Chemistry 81:9, pages 1905-1908.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova & L. I. Livantsova. (2011) Synthesis of pyridine-substituted hydroxymethylene diphosphinates containing unsaturated fragments. Russian Journal of General Chemistry 81:9, pages 1902-1904.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova & L. I. Livantsova. (2011) Synthesis of substituted hydroxymethylene diphosphonic acids and their derivatives containing unsaturated fragments. Russian Journal of General Chemistry 81:8, pages 1730-1731.
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Frank H. Ebetino, Anne-Marie L. Hogan, Shuting Sun, Maria K. Tsoumpra, Xuchen Duan, James T. Triffitt, Aaron A. Kwaasi, James E. Dunford, Bobby L. Barnett, Udo Oppermann, Mark W. Lundy, Alan Boyde, Boris A. Kashemirov, Charles E. McKenna & R. Graham G. Russell. (2011) The relationship between the chemistry and biological activity of the bisphosphonates. Bone 49:1, pages 20-33.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova & L. I. Livantsova. (2010) Synthesis of trimethylsilyl-substituted derivatives of aminomethylenediphosphorus-containing acids. Russian Journal of General Chemistry 80:9, pages 1889-1890.
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Andrey A. Prishchenko, Mikhail V. Livantsov, Olga P. Novikova, Ludmila I. Livantsova & Valery S. Petrosyan. (2010) Synthesis and functionalization of organophosphorus‐substituted amines with PCH 2 NH fragments . Heteroatom Chemistry 21:4, pages 236-241.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova & L. I. Livantsova. (2009) Syntheses of N-phenylaminomethylenediphosphonic and -diphosphinic acids and their derivatives. Russian Journal of General Chemistry 79:9, pages 1936-1938.
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Dalila Meziane, Julie Hardouin, Abdelhamid Elias, Erwann Guénin & Marc Lecouvey. (2009) Microwave Michaelis–Becker synthesis of diethyl phosphonates, tetraethyl diphosphonates, and their total or partial dealkylation. Heteroatom Chemistry 20:6, pages 369-377.
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Andrey A. Prishchenko, Mikhail V. Livantsov, Olga P. Novikova, Ludmila I. Livantsova & Valery S. Petrosyan. (2009) Synthesis of the new types of N‐substituted aminomethylenebisorganophosphorus acids and their derivatives. Heteroatom Chemistry 20:6, pages 319-324.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova, L. I. Livantsova & E. R. Milyaeva. (2008) Synthesis of 2-pyridylethylphosphinates containing 2,6-di-tert-butyl-4-methylphenol fragments. Russian Journal of General Chemistry 78:11, pages 2150-2153.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova, L. I. Livantsova, A. V. Maryashkin & E. R. Milaeva. (2007) Addition of trimethylsilyl esters of trivalent phosphorus acids to diethyl 3,5-di-tert-butyl-4-hydroxybenzoylphosphonate. Russian Journal of General Chemistry 77:8, pages 1477-1479.
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A. A. Prishchenko, M. V. Livantsov, O. P. Novikova, L. I. Livantsova, A. V. Maryashkin & E. R. Milaeva. (2007) Reactions of trimethylsilyl esters of trivalent phosphorus acids with 3,5-di-tert-butyl-4-hydroxybenzoyl chloride. Russian Journal of General Chemistry 77:8, pages 1474-1476.
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Jennifer E.I. Wright, Sebastien A. Gittens, Geeti Bansal, Pavel I. Kitov, Dennis Sindrey, Cezary Kucharski & Hasan Uludağ. (2006) A comparison of mineral affinity of bisphosphonate–protein conjugates constructed with disulfide and thioether linkages. Biomaterials 27:5, pages 769-784.
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Yuliya V. Rassukana, Petro P. Onys'ko, Kateryna O. Davydova & Anatolii D. Sinitsa. (2004) A new reaction of phosphorylated N-sulfonylimines with hydrophosphoryl agents involving C→N transfer of phosphoryl groups. Tetrahedron Letters 45:20, pages 3899-3902.
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