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Research Article

ATM Mutations in Sporadic Lymphoid Tumours

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Pages 1563-1571 | Published online: 01 Jul 2009

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Ceri E. Oldreive, Philip J. Byrd, Grant S. Stewart, Alexander J. Taylor, Sana Farhat, Anna Skowronska, Edward Smith, Manoj Raghavan, Dragana Janic, Lidija Dokmanovic, Sam Clokie, Nicholas Davies, Marwan Kwok, Guy Pratt, Shankara Paneesha, Paul Moss, Tatjana Stankovic & Malcolm Taylor. (2019) PALB2 variant status in hematological malignancies – a potential therapeutic target?. Leukemia & Lymphoma 60:7, pages 1823-1826.
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Eiji Kubota, Christopher T Williamson, Ruiqiong Ye, Anifat Elegbede, Lars Peterson, Susan P Lees-Miller & D Gwyn Bebb. (2014) Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines. Cell Cycle 13:13, pages 2129-2137.
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Gerard Lozanski, Amy S. Ruppert, Nyla A. Heerema, Arletta Lozanski, David M. Lucas, Amber Gordon, John G. Gribben, Vicki A. Morrison, Kanti M. Rai, Guido Marcucci, Richard A. Larson & John C. Byrd. (2012) Variations of the ataxia telangiectasia mutated gene in patients with chronic lymphocytic leukemia lack substantial impact on progression-free survival and overall survival: a Cancer and Leukemia Group B study. Leukemia & Lymphoma 53:9, pages 1743-1748.
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Xiaojun Liu, Hagop Kantarjian & William Plunkett. (2012) Sapacitabine for cancer. Expert Opinion on Investigational Drugs 21:4, pages 541-555.
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John D. Dickinson, Jamie Gilmore, Javeed Iqbal, Warren Sanger, James C. Lynch, John Chan, Philip J. Bierman & Shantaram S. Joshi. (2006) 11q22.3 deletion in B-chronic lymphocytic leukemia is specifically associated with bulky lymphadenopathy and ZAP-70 expression but not reduced expression of adhesion/cell surface receptor molecules. Leukemia & Lymphoma 47:2, pages 231-244.
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Articles from other publishers (64)

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Xiao Jiang, Amanda O'Neill, Katherine R. Smith, Zhongwu Lai, Keren Carss, Quanli Wang & Slavé Petrovski. (2022) Uncovering variable neoplasms between ATM protein‐truncating and common missense variants using 394 694 UK Biobank exomes . Genes, Chromosomes and Cancer 61:9, pages 523-529.
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Panruo Jiang, Aakash Desai & Haige Ye. (2021) Progress in molecular feature of smoldering mantle cell lymphoma. Experimental Hematology & Oncology 10:1.
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Veronica Ortega, Christina Mendiola, Juana Rodriguez, William EhmanJr.Jr., You-Wen Qian & Gopalrao Velagaleti. (2021) Bi-allelic amplification of ATM gene in blastoid variant of mantle cell lymphoma: a novel mechanism of inactivation due to chromoanagenesis?. Molecular Cytogenetics 14:1.
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Sabrina Putti, Alessandro Giovinazzo, Matilde Merolle, Maria Laura Falchetti & Manuela Pellegrini. (2021) ATM Kinase Dead: From Ataxia Telangiectasia Syndrome to Cancer. Cancers 13:21, pages 5498.
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Sang-Yong Shin, Hyeonah Lee, Seung-Tae Lee, Jong Rak Choi, Chul Won Jung, Hong Hoe Koo & Sun-Hee Kim. (2021) Recurrent somatic mutations and low germline predisposition mutations in Korean ALL patients. Scientific Reports 11:1.
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Kavita Bhalla, Sausan Jaber, Kayla Reagan, Arielle Hamburg, Karen F. Underwood, Aditya Jhajharia, Maninder Singh, Binny Bhandary, Shambhu Bhat, Nahid M. Nanaji, Ruching Hisa, Carrie McCracken, Heather Huot Creasy, Rena G. Lapidus, Tami Kingsbury, Dirk Mayer, Brian Polster & Ronald B. Gartenhaus. (2020) SIRT3, a metabolic target linked to ataxia-telangiectasia mutated (ATM) gene deficiency in diffuse large B-cell lymphoma. Scientific Reports 10:1.
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Alejandro Álvarez-Quilón, José Terrón-Bautista, Irene Delgado-Sainz, Almudena Serrano-Benítez, Rocío Romero-Granados, Pedro Manuel Martínez-García, Silvia Jimeno-González, Cristina Bernal-Lozano, Cristina Quintero, Lourdes García-Quintanilla & Felipe Cortés-Ledesma. (2020) Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency. Nature Communications 11:1.
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M. Cross & C. Dearden. (2019) B and T cell prolymphocytic leukaemia. Best Practice & Research Clinical Haematology 32:3, pages 217-228.
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Isabella Faraoni, Manuela Giansanti, Maria Teresa Voso, Francesco Lo-Coco & Grazia Graziani. (2019) Targeting ADP-ribosylation by PARP inhibitors in acute myeloid leukaemia and related disorders. Biochemical Pharmacology 167, pages 133-148.
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Rajib Ghosh, Debamitra Das & Sonia Franco. 2018. Chromosome Translocation. Chromosome Translocation 65 87 .
Masatoshi Takagi, Misa Yoshida, Yoshino Nemoto, Hiroyuki Tamaichi, Rika Tsuchida, Masafumi Seki, Kumiko Uryu, Noriko Hoshino, Rina Nishii, Satoshi Miyamoto, Masahiro Saito, Toshiaki Shimizu, Ryoji Hanada, Hideo Kaneko, Toshiyuki Fukao, Takatoshi Koyama, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Yusuke Sato, Yoichi Fujii, Keisuke Kataoka, Yusuke Okuno, Kenichi Yoshida, Tomohiro Morio, Akira Oka, Miki Ohira, Yasuhide Hayashi, Akira Nakagawara, Seishi Ogawa, Shuki Mizutani & Junko Takita. (2017) Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor. JNCI: Journal of the National Cancer Institute 109:11.
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Chen Wang, Nicholas Jette, Daniel Moussienko, D. Gwyn Bebb & Susan P. Lees-Miller. (2017) ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib. Translational Oncology 10:2, pages 190-196.
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Ling Li, Tao Zhu, Yuan-Feng Gao, Wei Zheng, Chen-Jing Wang, Ling Xiao, Ma-Sha Huang, Ji-Ye Yin, Hong-Hao Zhou & Zhao-Qian Liu. (2016) Targeting DNA Damage Response in the Radio(Chemo)therapy of Non-Small Cell Lung Cancer. International Journal of Molecular Sciences 17:6, pages 839.
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Marila Cordeiro‐Stone, John J. McNulty, Christopher D. Sproul, Paul D. Chastain, Eugene Gibbs‐Flournoy, Yingchun Zhou, Craig Carson, Shangbang Rao, David L. Mitchell, Dennis A. Simpson, Nancy E. Thomas, Joseph G. Ibrahim & William K. Kaufmann. (2015) Effective intra‐S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines. Pigment Cell & Melanoma Research 29:1, pages 68-80.
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Wynand P. Roos, Adam D. Thomas & Bernd Kaina. (2015) DNA damage and the balance between survival and death in cancer biology. Nature Reviews Cancer 16:1, pages 20-33.
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Frank P. Vendetti, Alan Lau, Sandra Schamus, Thomas P. Conrads, Mark J. O’Connor & Christopher J. Bakkenist. (2015) The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo . Oncotarget 6:42, pages 44289-44305.
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Karen S. HathcockHesed M. Padilla-NashJordi CampsDong-Mi ShinDaniel TrinerArthur L. ShafferIIIIII, Robert W. MaulSeth M. Steinberg, Patricia J. Gearhart, Louis M. StaudtHerbert C. MorseIIIIII, Thomas RiedRichard J. Hodes. (2015) ATM deficiency promotes development of murine B-cell lymphomas that resemble diffuse large B-cell lymphoma in humans. Blood 126:20, pages 2291-2301.
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Jana Prochazkova, Shinya Sakaguchi, Michel Owusu, Abdelghani Mazouzi, Marc Wiedner, Georgia Velimezi, Martin Moder, Gleb Turchinovich, Anastasiya Hladik, Elisabeth Gurnhofer, Adrian Hayday, Axel Behrens, Sylvia Knapp, Lukas Kenner, Wilfried Ellmeier & Joanna I. Loizou. (2015) DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation. PLOS Genetics 11:11, pages e1005645.
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Haley M. Simpson, Rashid Z. Khan, Chang Song, Deva Sharma, Kavitha Sadashivaiah, Aki Furusawa, Xinyue Liu, Sushma Nagaraj, Naomi Sengamalay, Lisa Sadzewicz, Luke J. Tallon, Qing C. Chen, Ferenc Livak, Aaron P. Rapoport, Amy Kimball & Arnob Banerjee. (2015) Concurrent Mutations in ATM and Genes Associated with Common γ Chain Signaling in Peripheral T Cell Lymphoma. PLOS ONE 10:11, pages e0141906.
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Wenxia JiangBrian J. LeeChen LiRichard L. DuboisMonica Gostissa, Frederick W. Alt & Shan Zha. (2015) Aberrant TCRδ rearrangement underlies the T-cell lymphocytopenia and t(12;14) translocation associated with ATM deficiency. Blood 125:17, pages 2665-2668.
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Jennifer A. Bennett & Michael G. Bayerl. (2015) Epstein-Barr Virus–associated Extranodal Marginal Zone Lymphoma of Mucosa-associated Lymphoid Tissue (MALT Lymphoma) Arising in the Parotid Gland of a Child With Ataxia Telangiectasia. Journal of Pediatric Hematology/Oncology 37:2, pages e114-e117.
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Andy C. Hsi, Diane H. Robirds, Jingqin Luo, Friederike H. Kreisel, John L. Frater & TuDung T. Nguyen. (2014) T-cell Prolymphocytic Leukemia Frequently Shows Cutaneous Involvement and Is Associated With Gains of MYC, Loss of ATM, and TCL1A Rearrangement. American Journal of Surgical Pathology 38:11, pages 1468-1483.
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Xuesong Li, Nigel J O’Neil, Noushin Moshgabadi & Philip Hieter. (2014) Synthetic Cytotoxicity: Digenic Interactions with TEL1/ATM Mutations Reveal Sensitivity to Low Doses of Camptothecin. Genetics 197:2, pages 611-623.
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Ian Maze, Kyung-Min Noh, Alexey A. Soshnev & C. David Allis. (2014) Every amino acid matters: essential contributions of histone variants to mammalian development and disease. Nature Reviews Genetics 15:4, pages 259-271.
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Enea Gino Di Domenico, Elena Romano, Paola Del Porto & Fiorentina Ascenzioni. (2014) Multifunctional Role of ATM/Tel1 Kinase in Genome Stability: From the DNA Damage Response to Telomere Maintenance. BioMed Research International 2014, pages 1-17.
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Peter J. McKinnon. (2012) ATM and the Molecular Pathogenesis of Ataxia Telangiectasia. Annual Review of Pathology: Mechanisms of Disease 7:1, pages 303-321.
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Heather L. Armata, Punita Shroff, David E. Garlick, Krista Penta, Andrew R. Tapper & Hayla K. Sluss. (2011) Loss of p53 Ser18 and Atm Results in Embryonic Lethality without Cooperation in Tumorigenesis. PLoS ONE 6:9, pages e24813.
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