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Research Article

Role of Apo2L/TRAIL and Bcl-2-family Proteins in Apoptosis of Multiple Myeloma

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Pages 1209-1214 | Received 15 Nov 2002, Published online: 03 Aug 2009

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Jiajun Liu, Renwei Huang, Dongjun Lin, Xiangyuan Wu, Jun Peng, Qu Lin, Xianglin Pan, Maohong Zhang, Ming Hou & Feng Chen. (2005) Apoptotic effect of oridonin on NB4 cells and its mechanism. Leukemia & Lymphoma 46:4, pages 593-597.
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Shirui Dai, Chao Wang, Lemeng Feng, Cheng Zhang, Wulong Zhang, Ye He, Xuezhi Zhou, Xiaobo Xia, Baihua Chen & Weitao Song. (2022) Protective activity of tert-butylhydroquinone against oxidative stress and apoptosis induced by glutamate agonizts in R28 cells and mice retina. Biomedicine & Pharmacotherapy 152, pages 113117.
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Emine Öksüzoğlu & Gül Kozalak. (2021) Inhibition of apoptosis may lead to the development of bortezomib resistance in multiple myeloma cancer cells. Turkish Journal of Biochemistry 46:1, pages 65-71.
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Radhika Bansal, Sagar Rakshit, Weiguo Han & Shaji Kumar. (2021) Modulation of Apoptosis Pathways in the Biology and Treatment of Multiple Myeloma. Oncology & Haematology 17:1, pages 48.
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Yoo-Kyung Cho, Sang-Il Kim, Kee-Yong Ha, Young-Hoon Kim, Hyung-Youl Park & Chang-Ki Min. (2019) Increased Osteoblastic Activity Suppressed Proliferation of Multiple Myeloma Plasma Cells. Spine 44:7, pages E384-E392.
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Baoyue Ding, Wei Zhang, Xin Wu, Jeffrey Wang, Chen Xie, Xuan Huang, Shuyu Zhan, Yongxia Zheng, Yueyan Huang, Ningyin Xu, Xueying Ding & Shen Gao. (2016) DR5 mAb-conjugated, DTIC-loaded immuno-nanoparticles effectively and specifically kill malignant melanoma cells in vivo . Oncotarget 7:35, pages 57160-57170.
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Hao Yaning, Zhao Fei, Luo Yuanyuan, Zhang Mei & Li Shasha. (2016) Inhibitory effect of oridonin on proliferation of RPMI8226 cells and the possible underlying mechanism. Journal of Traditional Chinese Medicine 36:2, pages 225-230.
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Mohamed M. Hafez, Naif O. Al-Harbi, Ali Rashed Al-Hoshani, Khaled A. Al-hosaini, Shakir D. Al Shrari, Salim S. Al Rejaie, Mohamed M. Sayed-Ahmed & Othman A. Al-Shabanah. (2015) Hepato-protective effect of rutin via IL-6/STAT3 pathway in CCl4-induced hepatotoxicity in rats. Biological Research 48:1.
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WENWEN ZHOU, HUYING CHEN, XIULI HONG, XIAOQING NIU & QUANYI LU. (2014) Knockdown of DNA methyltransferase-1 inhibits proliferation and derepresses tumor suppressor genes in myeloma cells. Oncology Letters 8:5, pages 2130-2134.
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Khurum H. Khan, Montserrat Blanco-Codesido & L. Rhoda Molife. (2014) Cancer therapeutics: Targeting the apoptotic pathway. Critical Reviews in Oncology/Hematology 90:3, pages 200-219.
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Kalyan J. Gangavarapu, Alok Bhushan, James C. K. Lai & Christopher K. Daniels. (2013) Differential Regulation of Cytochrome C Release in Dexamethasone-Resistant 7TD1 Cells. Journal of Cancer Therapy 04:04, pages 835-842.
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Shuhong Zhang, Attaya Suvannasankha, Colin D. Crean, Valerie L. White, Ching‐Shih Chen & Sherif S. Farag. (2010) The novel histone deacetylase inhibitor, AR‐42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells. International Journal of Cancer 129:1, pages 204-213.
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WenJuan Chen, ZhiChao Zhang, Wei Han, ChangJi Yuan, PeiRan Xu & Le Han. (2010) Preclinical studies of S1 in K562 cell line and primary chronic myeloid leukemia cells shown synergistic effect with Cytosine Arabinoside Hydrochloride. Preclinical studies of S1 in K562 cell line and primary chronic myeloid leukemia cells shown synergistic effect with Cytosine Arabinoside Hydrochloride.
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Jiri Minarik, Vlastimil Scudla, Marta Ordeltova, Jaroslav Bacovsky, Tomas Pika & Katerina Langova. (2009) Prognostic significance of apoptotic index in multiple myeloma patients treated by conventional therapy and novel agents, thalidomide and bortezomib. European Journal of Haematology 83:6, pages 528-534.
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Lia Elena Perez, Nancy Parquet, Kenneth Shain, Ramadevi Nimmanapalli, Melissa Alsina, Claudio Anasetti & William Dalton. (2008) Bone Marrow Stroma Confers Resistance to Apo2 Ligand/TRAIL in Multiple Myeloma in Part by Regulating c-FLIP. The Journal of Immunology 180:3, pages 1545-1555.
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Faustino Mollinedo. 2009. Myeloma Therapy. Myeloma Therapy 393 419 .
Shuhong Zhang, Attaya Suvannasankha, Colin D. Crean, Valerie L. White, Amy Johnson, Ching-Shih Chen & Sherif S. Farag. (2007) OSU-03012, a Novel Celecoxib Derivative, Is Cytotoxic to Myeloma Cells and Acts through Multiple Mechanisms. Clinical Cancer Research 13:16, pages 4750-4758.
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Maria Gómez-Benito, Maria José Martinez-Lorenzo, Alberto Anel, Isabel Marzo & Javier Naval. (2007) Membrane expression of DR4, DR5 and caspase-8 levels, but not Mcl-1, determine sensitivity of human myeloma cells to Apo2L/TRAIL. Experimental Cell Research 313:11, pages 2378-2388.
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Luca Agnelli, Sonia Fabris, Silvio Bicciato, Dario Basso, Luca Baldini, Fortunato Morabito, Donata Verdelli, Katia Todoerti, Giorgio Lambertenghi-Deliliers, Luigia Lombardi & Antonino Neri. (2007) Upregulation of translational machinery and distinct genetic subgroups characterise hyperdiploidy in multiple myeloma. British Journal of Haematology 136:4, pages 565-573.
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Suzanne Trudel, A. Keith Stewart, Zhihua Li, Yanjun Shu, Sheng-Ben Liang, Young Trieu, Donna Reece, Josh Paterson, Dingyan Wang & Xiao-Yan Wen. (2007) The Bcl-2 Family Protein Inhibitor, ABT-737, Has Substantial Antimyeloma Activity and Shows Synergistic Effect with Dexamethasone and Melphalan. Clinical Cancer Research 13:2, pages 621-629.
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Sébastien Maillard, Juliette Gauduchon, Véronique Marsaud, Fabrice Gouilleux, Elisabeth Connault, Paule Opolon, Elias Fattal, Brigitte Sola & Jack-Michel Renoir. (2006) Improved antitumoral properties of pure antiestrogen RU 58668-loaded liposomes in multiple myeloma. The Journal of Steroid Biochemistry and Molecular Biology 100:1-3, pages 67-78.
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YanPing Hu, Gwyn Bebb, Sophia Tan, Rebecca Ng, Hong Yan, Jason R. Sartor, Lawrence D. Mayer & Marcel B. Bally. (2004) Antitumor Efficacy of Oblimersen Bcl-2 Antisense Oligonucleotide Alone and in Combination with Vinorelbine in Xenograft Models of Human Non–Small Cell Lung Cancer. Clinical Cancer Research 10:22, pages 7662-7670.
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Marcela Oancea, Aruna Mani, Mohamad A. Hussein & Alexandru Almasan. (2004) Apoptosis of Multiple Myeloma. International Journal of Hematology 80:3, pages 224-231.
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John J. Haddad. (2004) On the antioxidant mechanisms of Bcl-2: a retrospective of NF-κB signaling and oxidative stress. Biochemical and Biophysical Research Communications 322:2, pages 355-363.
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. (2003) Prolonged Gene Expression Following Erythrocyte-Mediated Delivery of TRAIL Plasmid DNA. Journal of Korean Pharmaceutical Sciences 33:4, pages 261-265.
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