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Research Article

The CC Genotype of the C825T Polymorphism of the G Protein β3 Gene (GNB3) is Associated with a High Relapse Rate in Patients with Chronic Lymphocytic Leukaemia

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Pages 1739-1743 | Published online: 16 Nov 2010

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Fiona Murray & Paul A Insel. (2013) Targeting cAMP in chronic lymphocytic leukemia: a pathway-dependent approach for the treatment of leukemia and lymphoma. Expert Opinion on Therapeutic Targets 17:8, pages 937-949.
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Christian Dominik Fingas, Antonios Katsounas, Alisan Kahraman, Winfried Siffert, Christoph Jochum, Guido Gerken, Holger Nückel & Ali Canbay. (2010) Prognostic Assessment of Three Single-Nucleotide Polymorphisms (GNB3 825C>T, BCL2-938C>A, MCL1-386C>G) in Extrahepatic Cholangiocarcinoma. Cancer Investigation 28:5, pages 472-478.
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Articles from other publishers (12)

Yajun Shen, Lingyu Li, Yunping Lu, Min Zhang, Xin Huang & Xiaofei Tang. (2021) Establishment and Validation of a Comprehensive Prognostic Model for Patients With HNSCC Metastasis. Frontiers in Genetics 12.
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Ali Amin Asnafi, Niloofar Farshchi, Abbas Khosravi, Neda Ketabchi, Masumeh Maleki Behzad & Saeid Shahrabi. (2018) Significance of genetic polymorphisms in hematological malignancies: implications of risk factors for prognosis and relapse. memo - Magazine of European Medical Oncology 11:4, pages 330-344.
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Shahriar M. Khan, Rory Sleno, Sarah Gora, Peter Zylbergold, Jean-Philippe Laverdure, Jean-Claude Labbé, Gregory J. Miller & Terence E. Hébert. (2013) The Expanding Roles of G βγ Subunits in G Protein–Coupled Receptor Signaling and Drug Action . Pharmacological Reviews 65:2, pages 545-577.
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Fenna C. M. Sillé, Reuben Thomas, Martyn T. Smith, Lucia Conde & Christine F. Skibola. (2012) Post-GWAS Functional Characterization of Susceptibility Variants for Chronic Lymphocytic Leukemia. PLoS ONE 7:1, pages e29632.
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A. Eisenhardt, A. Scherag, M. Kempin, K.H. Jöckel & H. Rübben. (2011) Genotyp des GNB3-C825T-PolymorphismusGenotype of the GNB3 C825T polymorphism. Der Urologe 50:9, pages 1137-1142.
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Stefanie Klenke & Winfried Siffert. (2011) SNPs in genes encoding G proteins in pharmacogenetics. Pharmacogenomics 12:5, pages 633-654.
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Zuzana Saidak, Romuald Mentaverri & Edward M. Brown. (2009) The Role of the Calcium-Sensing Receptor in the Development and Progression of Cancer. Endocrine Reviews 30:2, pages 178-195.
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Goetz F. Lehnerdt, Peter Franz, Agnes Bankfalvi, Sara Grehl, Klaus Jahnke, Stephan Lang, Kurt W. Schmid, Winfried Siffert & Ulrich H. Frey. (2008) Association Study of the G-Protein β3 Subunit C825T Polymorphism with Disease Progression an Overall Survival in Patients with Head and Neck Squamous Cell Carcinoma. Cancer Epidemiology, Biomarkers & Prevention 17:11, pages 3203-3207.
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Kathrin Riemann, Henrike Struwe, Andreas Eisenhardt, Brigitte Obermaier, Kurt W. Schmid & Winfried Siffert. (2008) Characterization of intron-1 haplotypes of the G protein β4 subunit gene – association with survival and progression in patients with urothelial bladder carcinoma. Pharmacogenetics and Genomics 18:11, pages 999-1008.
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H. Clar, U. Langsenlehner, P. Krippl, W. Renner, A. Leithner, G. Gruber, G. Hofmann, B. Yazdani-Biuki, T. Langsenlehner & R. Windhager. (2007) A polymorphism in the G protein β3-subunit gene is associated with bone metastasis risk in breast cancer patients. Breast Cancer Research and Treatment 111:3, pages 449-452.
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Holger NückelUlrich H. FreyMaja BauLudger Sellmann, Jens Stanelle, Jan Dürig, Karl-Heinz Jöckel, Ulrich Dührsen & Winfried Siffert. (2006) Association of a novel regulatory polymorphism (−938C>A) in the BCL2 gene promoter with disease progression and survival in chronic lymphocytic leukemia. Blood 109:1, pages 290-297.
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H Nückel, U H Frey, J Dürig, U Dührsen & W Siffert. (2004) Methylenetetrahydrofolate reductase (MTHFR) gene 677C>T and 1298A>C polymorphisms are associated with differential apoptosis of leukemic B cells in vitro and disease progression in chronic lymphocytic leukemia. Leukemia 18:11, pages 1816-1823.
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