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Research Article

A Pilot Trial of Rituximab and Alemtuzumab Combination Therapy in Patients with Relapsed and/or Refractory Chronic Lymphocytic Leukemia (CLL)

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Pages 2269-2273 | Published online: 01 Jul 2009

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Clive S. Zent, Timothy G. Call, Deborah A. Bowen, Michael J. Conte, Betsy R. LaPlant, Thomas E. Witzig, Stephen M. Ansell & George J. Weiner. (2015) Early treatment of high risk chronic lymphocytic leukemia with alemtuzumab, rituximab and poly-(1-6)-beta-glucotriosyl-(1-3)- beta-glucopyranose beta-glucan is well tolerated and achieves high complete remission rates. Leukemia & Lymphoma 56:8, pages 2373-2378.
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Clive S. Zent, Wenting Wu, Deborah A. Bowen, Curtis A. Hanson, Adam M. Pettinger, Tait D. Shanafelt, Neil E. Kay, Jose F. Leis & Timothy G. Call. (2013) Addition of granulocyte macrophage colony stimulating factor does not improve response to early treatment of high-risk chronic lymphocytic leukemia with alemtuzumab and rituximab. Leukemia & Lymphoma 54:3, pages 476-482.
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Nisar A. Baig, Ronald P. Taylor, Margaret A. Lindorfer, Amy K. Church, Betsy R. Laplant, Emily S. Pavey, Grzegorz S. Nowakowski & Clive S. Zent. (2012) Complement dependent cytotoxicity in chronic lymphocytic leukemia: ofatumumab enhances alemtuzumab complement dependent cytotoxicity and reveals cells resistant to activated complement. Leukemia & Lymphoma 53:11, pages 2218-2227.
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Stéphane Lepretre, Uli Jäger, Ann Janssens, Veronique Leblond, Eugene Nikitin, Tadeusz Robak & Clemens-Martin Wendtner. (2012) The value of rituximab for the treatment of fludarabine-refractory chronic lymphocytic leukemia: a systematic review and qualitative analysis of the literature. Leukemia & Lymphoma 53:5, pages 820-829.
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Tadeusz Robak. (2012) Rituximab for chronic lymphocytic leukemia. Expert Opinion on Biological Therapy 12:4, pages 503-515.
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Aisha Masood, Taimur Sher, Aneel Paulus, Kena C Miller, Kasyapa S Chitta & Asher Chanan-Khan. (2011) Targeted treatment for chronic lymphocytic leukemia. OncoTargets and Therapy 4, pages 169-183.
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Chadi Nabhan, Neil Dalal, Jayesh Mehta & Neil E. Kay. (2011) Biologic agent activity in chronic lymphocytic leukemia: a framework for future therapies. Leukemia & Lymphoma 52:3, pages 374-386.
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Alessandra Tedeschi, Eleonora Vismara, Francesca Ricci, Enrica Morra & Marco Montillo. (2010) The spectrum of use of rituximab in chronic lymphocytic leukemia. OncoTargets and Therapy 3, pages 227-246.
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Aref Al-Kali, William Wierda, Michael Keating & Susan O’Brien. (2010) Critical appraisal of the role of rituximab in the treatment of patients with previously untreated or treated chronic lymphocytic leukemia (CLL). Journal of Blood Medicine 1, pages 115-122.
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Tadeusz Robak, Ewa Lech-Maranda & Pawel Robak. (2010) Rituximab plus fludarabine and cyclophosphamide or other agents in chronic lymphocytic leukemia. Expert Review of Anticancer Therapy 10:10, pages 1529-1543.
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Myron S. Czuczman & Stephanie A. Gregory. (2010) The future of CD20 monoclonal antibody therapy in B-cell malignancies. Leukemia & Lymphoma 51:6, pages 983-994.
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Marco Montillo, Francesca Ricci, Sara Miqueleiz, Alessandra Tedeschi & Enrica Morra. (2008) Alemtuzumab in the treatment of fludarabine refractory B-cell chronic lymphocytic leukemia (CLL). Biologics: Targets and Therapy 2:1, pages 41-52.
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Tadeusz Robak. (2008) Alemtuzumab for B-cell chronic lymphocytic leukemia. Expert Review of Anticancer Therapy 8:7, pages 1033-1051.
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Mohamed A Kharfan-Dabaja, Rabih Fahed, Mohamad Hussein & Edgardo S Santos. (2007) Evolving role of monoclonal antibodies in the treatment of chronic lymphocytic leukemia. Expert Opinion on Investigational Drugs 16:11, pages 1799-1815.
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Alessandra Ferrajoli, Stefan Faderl & Michael J Keating. (2006) Monoclonal antibodies in chronic lymphocytic leukemia. Expert Review of Anticancer Therapy 6:9, pages 1231-1238.
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