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Leukemia & Lymphoma Volume 47, 2006 - Issue 10
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A humanized HLA-DR antibody (hu1D10, apolizumab) in combination with granulocyte colony-stimulating factor (filgrastim) for the treatment of non-Hodgkin's lymphoma: A pilot study

Juergen Rech Department of Medicine III, University of Erlangen-Nueremberg, GermanyCorrespondence[email protected]
,
Roland Repp Division for Stem Cell and Immunotherapy, Second Medical Department, University of Kiel, Germany
,
Dorit Rech Department of Medicine III, University of Erlangen-Nueremberg, Germany
,
Bernhard Stockmeyer Department of Medicine III, University of Erlangen-Nueremberg, Germany
,
Michael Dechant Division of Nephrology, University of Schleswig-Holstein, Campus Kiel, Germany
,
Gerald Niedobitek Institute for Pathology, University of Erlangen-Nueremberg, Germany
,
Martin Gramatzki Division for Stem Cell and Immunotherapy, Second Medical Department, University of Kiel, Germany
&
Thomas Valerius Division of Nephrology, University of Schleswig-Holstein, Campus Kiel, Germany
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Pages 2147-2154 | Received 17 Feb 2006, Accepted 12 Apr 2006, Published online: 01 Jul 2009

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Rhona Stein, Cheryl Balkman, Susan Chen, Kenneth Rassnick, Margaret Mcentee, Rodney Page & David M. Goldenberg. (2011) Evaluation of anti-human leukocyte antigen-DR monoclonal antibody therapy in spontaneous canine lymphoma. Leukemia & Lymphoma 52:2, pages 273-284.
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Articles from other publishers (22)

Paula M. Fracasso, Sherry A. Goodner, Jonathan D. Wildi, Michael J. Naughton, Gerald P. Linette, Ramaswamy Govindan, Benjamin R. Tan, Kristie A. Blum, Gary J. Jones, Tillman E. Pearce, Daniel J. Levitt & Gerald H. Clamon. (2022) A Phase I Study of Apolizumab, an Anti-HLA-DR ß-chain Monoclonal Antibody, in Patients With Solid Tumor Malignancies. American Journal of Clinical Oncology 45:7, pages 294-297.
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Kin Man Au, Rod Balhorn, Monique C. Balhorn, Steven I. Park & Andrew Z. Wang. (2018) High-Performance Concurrent Chemo-Immuno-Radiotherapy for the Treatment of Hematologic Cancer through Selective High-Affinity Ligand Antibody Mimic-Functionalized Doxorubicin-Encapsulated Nanoparticles. ACS Central Science 5:1, pages 122-144.
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Thomas M. Cardillo, Serengulam V. Govindan, Maria B. Zalath, Diane L. Rossi, Yang Wang, Chien-Hsing Chang & David M. Goldenberg. (2018) IMMU-140, a Novel SN-38 Antibody–Drug Conjugate Targeting HLA-DR, Mediates Dual Cytotoxic Effects in Hematologic Cancers and Malignant Melanoma. Molecular Cancer Therapeutics 17:1, pages 150-160.
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Monika Podhorecka, Justyna Markowicz, Agnieszka Szymczyk & Johannes Pawlowski. (2014) Target Therapy in Hematological Malignances: New Monoclonal Antibodies. International Scholarly Research Notices 2014, pages 1-16.
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Christian Schmidt & Martin H. Dreyling. 2013. Lymphoma. Lymphoma 157 175 .
Tadeusz Robak. 2013. Non-Hodgkin Lymphoma. Non-Hodgkin Lymphoma 191 212 .
D. Focosi, F. Maggi, M. Pistello, U. Boggi & F. Scatena. (2011) Immunosuppressive monoclonal antibodies: current and next generation. Clinical Microbiology and Infection 17:12, pages 1759-1768.
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Edmund A. RossiDiane L. Rossi, Thomas M. Cardillo, Rhona Stein, David M. Goldenberg & Chien-Hsing Chang. (2011) Preclinical studies on targeted delivery of multiple IFNα2b to HLA-DR in diverse hematologic cancers. Blood 118:7, pages 1877-1884.
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Edmund A. Rossi, Diane L. Rossi, Rhona Stein, David M. Goldenberg & Chien-Hsing Chang. (2010) A Bispecific Antibody-IFNα2b Immunocytokine Targeting CD20 and HLA-DR Is Highly Toxic to Human Lymphoma and Multiple Myeloma Cells. Cancer Research 70:19, pages 7600-7609.
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Sophie Dupire & Bertrand Coiffier. (2010) Targeted treatment and new agents in diffuse large B cell lymphoma. International Journal of Hematology 92:1, pages 12-24.
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Rhona SteinPankaj Gupta, Xiaochuan ChenThomas M. Cardillo, Richard R. Furman, Susan ChenChien-Hsing Chang & David M. Goldenberg. (2010) Therapy of B-cell malignancies by anti–HLA-DR humanized monoclonal antibody, IMMU-114, is mediated through hyperactivation of ERK and JNK MAP kinase signaling pathways. Blood 115:25, pages 5180-5190.
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Yvonne Guettinger, Karin Barbin, Matthias Peipp, Joerg Bruenke, Michael Dechant, Heike Horner, Doreen Thierschmidt, Thomas Valerius, Roland Repp, Georg H. Fey & Bernhard Stockmeyer. (2010) A Recombinant Bispecific Single-Chain Fragment Variable Specific for HLA Class II and FcαRI (CD89) Recruits Polymorphonuclear Neutrophils for Efficient Lysis of Malignant B Lymphoid Cells. The Journal of Immunology 184:3, pages 1210-1217.
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Robert O. Dillman. 2009. Principles of Cancer Biotherapy. Principles of Cancer Biotherapy 303 406 .
Christian Schmidt & Martin Dreyling. (2008) Therapy of Mantle Cell Lymphoma: Current Standards and Future Strategies. Hematology/Oncology Clinics of North America 22:5, pages 953-963.
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Jorge Castillo, Eric Winer & Peter Quesenberry. (2008) Newer monoclonal antibodies for hematological malignancies. Experimental Hematology 36:7, pages 755-768.
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Mitchell R. Smith. (2008) Antibodies and Hematologic Malignancies. The Cancer Journal 14:3, pages 184-190.
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. (2007) Current Awareness in Hematological Oncology. Hematological Oncology 25:3, pages 148-155.
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John M. Pagel, Anastasia Pantelias, Nathan Hedin, Shani Wilbur, Laura Saganic, Yukang Lin, Donald Axworthy, Donald K. Hamlin, D. Scott Wilbur, Ajay K. Gopal & Oliver W. Press. (2007) Evaluation of CD20, CD22, and HLA-DR Targeting for Radioimmunotherapy of B-Cell Lymphomas. Cancer Research 67:12, pages 5921-5928.
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Celeste Bello & Eduardo M. Sotomayor. (2007) Monoclonal Antibodies for B-Cell Lymphomas: Rituximab and Beyond. Hematology 2007:1, pages 233-242.
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