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Leukemia & Lymphoma Volume 47, 2006 - Issue 10
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Original

Association between the MTHFR A1298C polymorphism and increased risk of acute myeloid leukemia in Brazilian children

Flavio Jose da Costa Ramos Departamento de Genética, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil; Departmento de Biologia e Departamento de Ciências Fisiológicas, Instituto de Ciências Biologicas, Universidade de Pernambuco, Recife, Pernambuco, Brazil
,
Maria Tereza Cartaxo Muniz Departmento de Biologia e Departamento de Ciências Fisiológicas, Instituto de Ciências Biologicas, Universidade de Pernambuco, Recife, Pernambuco, Brazil
,
Vanessa Cavalcante Silva Departamento de Genética, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil
,
Marcela Araújo Centro Infantil Boldrini, Campinas, São Paulo, Brazil
,
Ednalva Pereira Leite Centro de Oncologia, Hospital Universitário Oswaldo Cruz, Recife, Pernambuco, Brazil
,
Elizabete Malaquias Freitas Departmento de Biologia e Departamento de Ciências Fisiológicas, Instituto de Ciências Biologicas, Universidade de Pernambuco, Recife, Pernambuco, Brazil
,
Crisiane Wais Zanrosso CPq-Instituto Nacional de Câncer, Divisão de Medicina Experimental, Rio de Janeiro, Brazil
,
Ana Hatagima Departamento de Genética, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil
,
Maricilda Palandi de Mello Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, São Paulo, Brazil
,
Jose Andrés Yunes Centro Infantil Boldrini, Campinas, São Paulo, Brazil
,
Terezinha de Jesus Marques-Salles Centro de Oncologia, Hospital Universitário Oswaldo Cruz, Recife, Pernambuco, Brazil
,
Neide Santos Departamento de Genética, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil
,
Silvia R. Brandalise Centro Infantil Boldrini, Campinas, São Paulo, Brazil
&
Maria S. Pombo-De-Oliveira CPq-Instituto Nacional de Câncer, Divisão de Medicina Experimental, Rio de Janeiro, BrazilCorrespondence[email protected]
 show all
Pages 2070-2075 | Received 25 Mar 2006, Accepted 11 May 2006, Published online: 01 Jul 2009

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Claudia Bănescu & Adrian P. Trifa. (2015) Methylenetetrahydrofolate reductase 677 C> T polymorphism is associated with acute myeloid leukemia. Leukemia & Lymphoma 56:4, pages 1172-1174.
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Márcia R. Amorim, Crisiane Wais Zanrosso, Isis Q. Magalhães, Simone C. Pereira, Alexandre Figueiredo, Mariana Emerenciano, Vitória Regia Pinheiro, Maria Lydia d'Andréa, Iêda M. Orioli, Sergio Koifman & Maria. S. Pombo-de-Oliveira. (2008) MTHFR 677C→T And 1298A→C POLYMORPHISMS IN CHILDREN WITH DOWN SYNDROME AND ACUTE MYELOID LEUKEMIA IN BRAZIL. Pediatric Hematology and Oncology 25:8, pages 744-750.
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Adi Gidron & Leonidas C. Platanias. (2006) MTHFR polymorphisms and the development of acute leukemia: Does it really matter?. Leukemia & Lymphoma 47:10, pages 2002-2003.
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Articles from other publishers (15)

Sabrina Torres-Loureiro, Mariana M Scudeler, Poliana XC Andrade, Julia Sampaio-Coelho, Igor H Nobre, Carolina Céspedes-Garro, Eduardo Tarazona-Santos, Adrián Llerena & Fernanda Rodrigues-Soares. (2022) Pharmacogenetics research in Brazil: a systematic review. Pharmacogenomics 23:4, pages 263-275.
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Samanta Celeste Garcia-Hernandez, Perla Meneses-Sanchez, Leonardo Martin Porchia, Enrique Torres-Rasgado, Ricardo Pérez-Fuentes & Martha Elba Gonzalez-Mejia. (2019) Differential effects of the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) on hematological malignancies among Latinos: a meta-analysis. Genetics and Molecular Biology 42:3, pages 549-559.
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Claudia Bănescu, Mihaela Iancu, Adrian P. Trifa, Ioan Macarie, Delia Dima & Minodora Dobreanu. (2014) The methylenetetrahydrofolate reductase (MTHFR) 677 C>T polymorphism increases the risk of developing chronic myeloid leukemia—a case-control study. Tumor Biology 36:4, pages 3101-3107.
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Rafaela Montalvão-de-AzevedoGisele M. VasconcelosFernando R. VargasLuiz Claudio ThulerMaria S. Pombo-de-OliveiraBeatriz de Camargo. (2015) RFC-1 80G>A Polymorphism in Case-Mother/Control-Mother Dyads Is Associated with Risk of Nephroblastoma and Neuroblastoma . Genetic Testing and Molecular Biomarkers 19:2, pages 75-81.
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Hairong He, Gonghao He, Taotao Wang, Jiangxia Cai, Yan Wang, Xiaowei Zheng, Yalin Dong & Jun Lu. (2014) Methylenetetrahydrofolate reductase gene polymorphisms contribute to acute myeloid leukemia and chronic myeloid leukemia susceptibilities: Evidence from meta-analyses. Cancer Epidemiology 38:5, pages 471-478.
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Song Dong, Yueling Liu & Jieping Chen. (2014) MTHFR gene polymorphism and risk of myeloid leukemia: a meta-analysis. Tumor Biology 35:9, pages 8913-8919.
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Min Tang, Shang-Qian Wang, Bian-Jiang Liu, Qiang Cao, Bing-Jie Li, Peng-Chao Li, Yong-Fei Li, Chao Qin & Wei Zhang. (2014) The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and tumor risk: evidence from 134 case–control studies. Molecular Biology Reports 41:7, pages 4659-4673.
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Yu-Tao Qin, Yong Zhang, Fang Wu, Yan Su, Ge-Ning Lu & Ren-Sheng Wang. (2014) Association between MTHFR Polymorphisms and Acute Myeloid Leukemia Risk: A Meta-Analysis. PLoS ONE 9:2, pages e88823.
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Alexander Semmler, Susanna Moskau, Holger Lutz, Peter Meyer & Michael Linnebank. (2011) Haplotype analysis of the 5,10-methylenetetrahydrofolate reductase (MTHFR) c.1298A>C (E429A) polymorphism. BMC Research Notes 4:1.
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Azza AG Tantawy, Eman A El-Bostany, Amira AM Adly, Mohammed Abou El Asrar, Eman A El-Ghouroury & Esmat E Abdulghaffar. (2010) Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia. Blood Coagulation & Fibrinolysis 21:1, pages 28-34.
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Said I. Ismail, Nida A. Ababneh, Yousef Khader, Ahmad A. Abu-Khader & Abdullah Awidi. (2009) Methylenetetrahydrofolate reductase genotype association with the risk of follicular lymphoma. Cancer Genetics and Cytogenetics 195:2, pages 120-124.
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Maria S. Pombo de Oliveira, Sergio Koifman, Gisele M. Vasconcelos, Mariana Emerenciano & Cristiane de Oliveira Novaes. (2009) Development and perspective of current Brazilian studies on the epidemiology of childhood leukemia. Blood Cells, Molecules, and Diseases 42:2, pages 121-125.
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C.-y. Liu, Y.-H. Hsu, P.-C. Pan, M.-T. Wu, C.-K. Ho, L. Su, X. Xu, Y. Li & D. C. Christiani. (2008) Maternal and offspring genetic variants of AKR1C3 and the risk of childhood leukemia. Carcinogenesis 29:5, pages 984-990.
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Cynara Gomes Barbosa, Claudio Lima Souza, José Pereira de Moura Neto, Maria da Glória Bomfim Arruda, José Henrique Barreto, Mitermayer Galvão Reis & Marilda Souza Goncalves. (2008) Methylenetetrahydrofolate reductase polymorphisms in myeloid leukemia patients from Northeastern Brazil. Genetics and Molecular Biology 31:1, pages 29-32.
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Fakhraddin Naghibalhossaini, Pooneh Mokarram & Islam Khalili. (2008) Easy detection of 5,10-methylenetetrahydrofolate reductase 1298A/C genotype by mutagenically separated PCR assay. Clinical Chemistry and Laboratory Medicine 46:7.
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