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Leukemia & Lymphoma Volume 58, 2017 - Issue 4
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Original Articles: Clinical

Biallelic ATM alterations detected at diagnosis identify a subset of treatment-naïve chronic lymphocytic leukemia patients with reduced overall survival similar to patients with p53 deletion

Carol Lozano-SantosHematology Department, Molecular Cytogenetics Unit, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; ;Institute of Research Puerta de Hierro-Majadahonda (IDIPHIM), Spain;
,
José A. García-VelaHematology Department, Hospital Universitario de Getafe, Madrid, Spain;
,
Nuria Pérez-SanzHematology Department, Molecular Cytogenetics Unit, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain;
,
Sara Nova-GurumetaHematology Department, Molecular Cytogenetics Unit, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain;
,
Belen Fernandez-CuevasHematology Department, Molecular Cytogenetics Unit, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain;
,
Natalia Gomez-LozanoInstitute of Research Puerta de Hierro-Majadahonda (IDIPHIM), Spain;
,
Margarita Sánchez-BeatoInstitute of Research Puerta de Hierro-Majadahonda (IDIPHIM), Spain;
,
Pedro Sanchez-GodoyHematology Departament, Hospital Severo Ochoa de Leganés, Madrid, Spain;
,
José Luis BuenoBlood Bank Unit, Hematology Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain
&
José A. Garcia-MarcoHematology Department, Molecular Cytogenetics Unit, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; Correspondence[email protected]
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Pages 859-865 | Received 21 Apr 2016, Accepted 09 Jul 2016, Published online: 08 Aug 2016

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Andrea Mareckova, Jitka Malcikova, Nikola Tom, Karol Pal, Lenka Radova, David Salek, Andrea Janikova, Mojmir Moulis, Jana Smardova, Leos Kren, Jiri Mayer & Martin Trbusek. (2019) ATM and TP53 mutations show mutual exclusivity but distinct clinical impact in mantle cell lymphoma patients. Leukemia & Lymphoma 60:6, pages 1420-1428.
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Articles from other publishers (7)

Veronika Navrkalova, Karla Plevova, Lenka Radova, Jakub Porc, Karol Pal, Jitka Malcikova, Sarka Pavlova, Michael Doubek, Anna Panovska, Jana Kotaskova & Sarka Pospisilova. (2023) Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment‐naïve CLL patients. British Journal of Haematology.
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Claudia Pérez‐Carretero, María Hernández‐Sánchez, Teresa González, Miguel Quijada‐Álamo, Marta Martín‐Izquierdo, Sandra Santos‐Mínguez, Cristina Miguel‐García, María‐Jesús Vidal, Alfonso García‐De‐Coca, Josefina Galende, Emilia Pardal, Carlos Aguilar, Manuel Vargas‐Pabón, Julio Dávila, Isabel Gascón‐Y‐Marín, José‐Ángel Hernández‐Rivas, Rocío Benito, Jesús‐María Hernández‐Rivas & Ana‐Eugenia Rodríguez‐Vicente. (2022) TRAF3 alterations are frequent in del‐3′ IGH chronic lymphocytic leukemia patients and define a specific subgroup with adverse clinical features . American Journal of Hematology 97:7, pages 903-914.
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Farnaz Baghaei Vaji, Arash Boroumand Nasr, Ali Rezvani, Hossein Ayatollahi, Sajad Goudarzi, Soroush Lavasani & Ramin Bagheri. (2021) Prognostic significance of ATM mutations in chronic lymphocytic leukemia: A meta-analysis. Leukemia Research 111, pages 106729.
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Miguel Quijada‐Álamo, Claudia Pérez‐Carretero, María Hernández‐Sánchez, Ana‐Eugenia Rodríguez‐Vicente, Ana‐Belén Herrero, Jesús‐María Hernández‐Sánchez, Marta Martín‐Izquierdo, Sandra Santos‐Mínguez, Mónica del Rey, Teresa González, Araceli Rubio‐Martínez, Alfonso García de Coca, Julio Dávila‐Valls, José‐Ángel Hernández‐Rivas, Helen Parker, Jonathan C. Strefford, Rocío Benito, José‐Luis Ordóñez & Jesús‐María Hernández‐Rivas. (2021) Dissecting the role of TP53 alterations in del(11q) chronic lymphocytic leukemia . Clinical and Translational Medicine 11:2.
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Kartik Viswanathan, Gail Roboz, Amy Chadburn & Susan Mathew. (2019) Chronic Myelogenous Leukemia Diagnosed in the Setting of Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. International Journal of Surgical Pathology 28:2, pages 216-224.
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Alain Mina, Jose Sandoval Sus, Elsa Sleiman, Javier Pinilla-Ibarz, Farrukh T. Awan & Mohamed A. Kharfan-Dabaja. (2018) Using prognostic models in CLL to personalize approach to clinical care: Are we there yet?. Blood Reviews 32:2, pages 159-166.
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Meaghan Wall & Lynda J. Campbell. 2018. Neoplastic Diseases of the Blood. Neoplastic Diseases of the Blood 853 902 .

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