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Leukemia & Lymphoma Volume 58, 2017 - Issue 5
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Original Articles: Research

Impact of ABC single nucleotide polymorphisms upon the efficacy and toxicity of induction chemotherapy in acute myeloid leukemia

Juan Eduardo Megías-VericatUnidad de Farmacogenética, Instituto Investigación Sanataria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain; ;Servicio de Farmacia, Área del Medicamento. Hospital Universitario y Politécnico La Fe Avda, Valencia, Spain; Correspondence[email protected] [email protected]
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Pau MontesinosServicio de Hematología y Hemoterapia. Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain;
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María José HerreroUnidad de Farmacogenética, Instituto Investigación Sanataria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain; ;Departamento Farmacología, Facultad de Medicina, Universidad de Valencia. Avda, Valencia, Spain; Correspondence[email protected] [email protected]
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Federico MoscardóServicio de Hematología y Hemoterapia. Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain;
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Virginia BosóUnidad de Farmacogenética, Instituto Investigación Sanataria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain; ;Servicio de Farmacia, Área del Medicamento. Hospital Universitario y Politécnico La Fe Avda, Valencia, Spain;
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Luis RojasUnidad de Farmacogenética, Instituto Investigación Sanataria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain; ;Department of Internal Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile. Avda, Santiago, Chile;
,
David Martínez-CuadrónServicio de Hematología y Hemoterapia. Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain;
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David HervásUnidad de Bioestadística, Instituto investigación Sanataria La Fe. Avda, Valencia, Spain;
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Blanca BoludaServicio de Hematología y Hemoterapia. Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain;
,
Ana García-RoblesServicio de Farmacia, Área del Medicamento. Hospital Universitario y Politécnico La Fe Avda, Valencia, Spain;
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Rebeca Rodríguez-VeigaServicio de Hematología y Hemoterapia. Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain;
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María Martín-CerezuelaServicio de Farmacia, Área del Medicamento. Hospital Universitario y Politécnico La Fe Avda, Valencia, Spain;
,
José CerveraServicio de Hematología y Hemoterapia. Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain;
,
Luis SendraDepartamento Farmacología, Facultad de Medicina, Universidad de Valencia. Avda, Valencia, Spain;
,
Jaime SanzServicio de Hematología y Hemoterapia. Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain;
,
Antonio MiguelDepartamento Farmacología, Facultad de Medicina, Universidad de Valencia. Avda, Valencia, Spain;
,
Ignacio LorenzoServicio de Hematología y Hemoterapia. Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain;
,
José Luis PovedaServicio de Farmacia, Área del Medicamento. Hospital Universitario y Politécnico La Fe Avda, Valencia, Spain;
,
Miguel Ángel SanzServicio de Hematología y Hemoterapia. Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain;
&
Salvador F. AliñoUnidad de Farmacogenética, Instituto Investigación Sanataria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain; ;Departamento Farmacología, Facultad de Medicina, Universidad de Valencia. Avda, Valencia, Spain; ;Unidad de Farmacología Clínica, Área del Medicamento, Hospital Universitario y Politécnico La Fe. Avda, Valencia, Spain
 show all
Pages 1197-1206 | Received 16 Jun 2016, Accepted 22 Aug 2016, Published online: 04 Oct 2016

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Henrike Bruckmueller & Ingolf Cascorbi. (2021) ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?. Expert Opinion on Drug Metabolism & Toxicology 17:4, pages 369-396.
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Juan Eduardo Megías-Vericat, David Martínez-Cuadrón, María José Herrero, Rebeca Rodríguez-Veiga, Antonio Solana-Altabella, Blanca Boluda, Octavio Ballesta-López, Isabel Cano, Evelyn Acuña-Cruz, José Cervera, José Luis Poveda, MiguelÁngel Sanz, Salvador F. Aliño & Pau Montesinos. (2021) Impact of combinations of single-nucleotide polymorphisms of anthracycline transporter genes upon the efficacy and toxicity of induction chemotherapy in acute myeloid leukemia. Leukemia & Lymphoma 62:3, pages 659-668.
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Articles from other publishers (25)

Ela Cerovska, Cyril Salek, David Kundrat, Sarka Sestakova, Adam Pesek, Ivana Brozinova, Monika Belickova & Hana Remesova. (2024) ABC transporters are predictors of treatment failure in acute myeloid leukaemia. Biomedicine & Pharmacotherapy 170, pages 115930.
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Ming‐Ming Ni, Ju‐Fei Yang, Jing Miao & Jin Xu. (2023) Association between genetic variants of transmembrane transporters and susceptibility to anthracycline‐induced cardiotoxicity: Current understanding and existing evidence. Clinical Genetics.
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Daniela Damiani & Mario Tiribelli. (2023) ABCG2 in Acute Myeloid Leukemia: Old and New Perspectives. International Journal of Molecular Sciences 24:8, pages 7147.
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Ofra Barnett‐Griness, Gad Rennert, Flavio Lejbkowicz, Mila Pinchev, Walid Saliba & Naomi Gronich. (2023) Association Between ABCG2 , ABCB1 , ABCC2 Efflux Transporter Single‐Nucleotide Variants and Irinotecan Adverse Effects in Patients With Colorectal Cancer: A Real‐Life Study . Clinical Pharmacology & Therapeutics 113:3, pages 704-711.
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Luz K. Yunis, Adriana Linares‐Ballesteros, Nelson Aponte, Gisela Barros, Johnny García, Laura Niño, Gloria Uribe, Edna Quintero & Juan J. Yunis. (2022) Pharmacogenetics of ABCB1 , CDA , DCK , GSTT1 , GSTM1 and outcomes in a cohort of pediatric acute myeloid leukemia patients from Colombia . Cancer Reports 6:3.
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Juan Eduardo Megías-Vericat, David Martínez-Cuadrón, Antonio Solana-Altabella, José Luis Poveda & Pau Montesinos. (2022) Systematic Review of Pharmacogenetics of ABC and SLC Transporter Genes in Acute Myeloid Leukemia. Pharmaceutics 14:4, pages 878.
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Sara Aslam, Sonia Ameer, N. A. Shabana & Mehboob Ahmed. (2021) Pharmacogenetics of induction therapy-related toxicities in childhood acute lymphoblastic leukemia patients treated with UKALL 2003 protocol. Scientific Reports 11:1.
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Raquel Alves, Ana Cristina Gonçalves, Sergio Rutella, António M. Almeida, Javier De Las Rivas, Ioannis P. Trougakos & Ana Bela Sarmento Ribeiro. (2021) Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical Relevance. Cancers 13:19, pages 4820.
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Kateryna Petrykey, Aziz M Rezgui, Mathilde Le Guern, Patrick Beaulieu, Pascal St-Onge, Simon Drouin, Laurence Bertout, Fan Wang, Jessica L Baedke, Yutaka Yasui, Melissa M Hudson, Marie-Josée Raboisson, Caroline Laverdière, Daniel Sinnett, Gregor U Andelfinger & Maja Krajinovic. (2021) Genetic factors in treatment-related cardiovascular complications in survivors of childhood acute lymphoblastic leukemia. Pharmacogenomics 22:14, pages 885-901.
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Agata Bikiewicz, Maciej Banach, Stephan von Haehling, Marek Maciejewski & Agata Bielecka‐Dabrowa. (2021) Adjuvant breast cancer treatments cardiotoxicity and modern methods of detection and prevention of cardiac complications. ESC Heart Failure 8:4, pages 2397-2418.
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Flavia Cunha Vasconcelos, Paloma Silva de Souza, Thaís Hancio, Fernanda Costas Casal de Faria & Raquel Ciuvalschi Maia. (2021) Update on drug transporter proteins in acute myeloid leukemia: Pathological implication and clinical setting. Critical Reviews in Oncology/Hematology 160, pages 103281.
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Carmelo Gurnari, Simona Pagliuca & Valeria Visconte. (2020) Deciphering the Therapeutic Resistance in Acute Myeloid Leukemia. International Journal of Molecular Sciences 21:22, pages 8505.
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Q Liu, M Hua, S Yan, C Zhang, R Wang, X Yang, F Han, M Hou & D Ma. (2020) Immunorelated gene polymorphisms associated with acute myeloid leukemia. Clinical and Experimental Immunology 201:3, pages 266-278.
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