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Leukemia & Lymphoma Volume 58, 2017 - Issue 12
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Original Articles: Research

Influence of cytarabine metabolic pathway polymorphisms in acute myeloid leukemia induction treatment

Juan Eduardo Megías-VericatUnidad de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe., Valencia, Spain; ;Servicio de Farmacia, Área del Medicamento, Hospital Universitario y Politécnico La Fe Avda, Valencia, Spain; Correspondence[email protected]
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Pau MontesinosServicio de Hematología y Hemoterapia, Hospital Universitario y Politécnico La Fe, Avda, Valencia, Spain; View further author information
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María José HerreroUnidad de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe., Valencia, Spain; ;Departamento Farmacología, Facultad de Medicina, Universidad de Valencia. Avda., Valencia, Spain; View further author information
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Federico MoscardóServicio de Hematología y Hemoterapia, Hospital Universitario y Politécnico La Fe, Avda, Valencia, Spain; View further author information
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Virginia BosóUnidad de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe., Valencia, Spain; ;Servicio de Farmacia, Área del Medicamento, Hospital Universitario y Politécnico La Fe Avda, Valencia, Spain; View further author information
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David Martínez-CuadrónServicio de Hematología y Hemoterapia, Hospital Universitario y Politécnico La Fe, Avda, Valencia, Spain; View further author information
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Luis RojasUnidad de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe., Valencia, Spain; ;Department of Internal Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile; View further author information
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Rebeca Rodríguez-VeigaServicio de Hematología y Hemoterapia, Hospital Universitario y Politécnico La Fe, Avda, Valencia, Spain; View further author information
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Blanca BoludaServicio de Hematología y Hemoterapia, Hospital Universitario y Politécnico La Fe, Avda, Valencia, Spain; View further author information
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Luis SendraUnidad de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe., Valencia, Spain; ;Departamento Farmacología, Facultad de Medicina, Universidad de Valencia. Avda., Valencia, Spain; View further author information
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José CerveraServicio de Hematología y Hemoterapia, Hospital Universitario y Politécnico La Fe, Avda, Valencia, Spain; View further author information
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José Luis PovedaServicio de Farmacia, Área del Medicamento, Hospital Universitario y Politécnico La Fe Avda, Valencia, Spain; View further author information
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Miguel Ángel SanzServicio de Hematología y Hemoterapia, Hospital Universitario y Politécnico La Fe, Avda, Valencia, Spain; View further author information
&
Salvador F. AliñoUnidad de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitario y Politécnico La Fe., Valencia, Spain; ;Departamento Farmacología, Facultad de Medicina, Universidad de Valencia. Avda., Valencia, Spain; ;Unidad de Farmacología Clínica, Área del Medicamento, Hospital Universitario y Politécnico La Fe. Avda, Valencia, SpainView further author information
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Pages 2880-2894 | Received 29 Nov 2016, Accepted 19 Apr 2017, Published online: 02 Jun 2017

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Na Wang, Aakash Desai, Bei Ge, Wenya Li, Xianghong Jin, Hongzhao Bai, Kang Yu & Haige Ye. (2020) Prognostic value of hypoalbuminemia at diagnosis in de novo non-M3 acute myeloid leukemia. Leukemia & Lymphoma 61:3, pages 641-649.
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Luz K. Yunis, Adriana Linares‐Ballesteros, Nelson Aponte, Gisela Barros, Johnny García, Laura Niño, Gloria Uribe, Edna Quintero & Juan J. Yunis. (2022) Pharmacogenetics of ABCB1 , CDA , DCK , GSTT1 , GSTM1 and outcomes in a cohort of pediatric acute myeloid leukemia patients from Colombia . Cancer Reports 6:3.
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Johana Díaz‐Santa, Rocío Rodríguez‐Romanos, Rosa Coll, Gemma Osca, Marta Pratcorona, Marta González‐Bártulos, Ana Garrido, Anna Angona, Carme Talarn, Mar Tormo, Montserrat Arnan, Susanna Vives, Olga Salamero, Esperanza Tuset, Natàlia Lloveras, Isabel Díez, Lurdes Zamora, Joan Bargay, Antonia Sampol, David Cruz, Jordi Vila, Marta Sitges, Antoni Garcia, Ferran Vall‐Llovera, Jordi Esteve, Jorge Sierra & David Gallardo. (2022) 5′‐nucleotidase, cytosolic II genotype, and clinical outcome in patients with acute myeloid leukemia with intermediate‐risk cytogenetics. European Journal of Haematology 109:6, pages 755-764.
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Álvaro Pinto-Merino, Jorge Labrador, Pablo Zubiaur, Raquel Alcaraz, María José Herrero, Pau Montesinos, Francisco Abad-Santos & Miriam Saiz-Rodríguez. (2022) Role of Pharmacogenetics in the Treatment of Acute Myeloid Leukemia: Systematic Review and Future Perspectives. Pharmaceutics 14:3, pages 559.
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Carmelo Gurnari, Simona Pagliuca & Valeria Visconte. (2020) Deciphering the Therapeutic Resistance in Acute Myeloid Leukemia. International Journal of Molecular Sciences 21:22, pages 8505.
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Pitchaya Jaruvijitrattana & Kumutnart Chanprapaph. (2019) Bilateral Ear Swelling and Erythema after Chemotherapy: A Case Report of Ara-C Ears. Case Reports in Dermatology 11:2, pages 226-232.
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Samuel H. Fu, Alexander H. Flannery & Melissa L. Thompson Bastin. (2018) Acute Hepatotoxicity After High-Dose Cytarabine for the Treatment of Relapsed Acute Myeloid Leukemia: A Case Report. Hospital Pharmacy 54:3, pages 160-164.
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Ke-Wei Zhu, Peng Chen, Dao-Yu Zhang, Han Yan, Han Liu, Li-Na Cen, Yan-Ling Liu, Shan Cao, Gan Zhou, Hui Zeng, Shu-Ping Chen, Xie-Lan Zhao & Xiao-Ping Chen. (2018) Association of genetic polymorphisms in genes involved in Ara-C and dNTP metabolism pathway with chemosensitivity and prognosis of adult acute myeloid leukemia (AML). Journal of Translational Medicine 16:1.
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Radosław Mlak, Tomasz Powrózek, Anna Brzozowska, Iwona Homa-Mlak, Marcin Mazurek & Teresa Małecka-Massalska. (2018) RRM1 gene expression evaluated in the liquid biopsy (blood cfRNA) as a non-invasive, predictive factor for radiotherapy-induced oral mucositis and potential prognostic biomarker in head and neck cancer patients. Cancer Biomarkers 22:4, pages 657-667.
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Petra C. Bachour & Stephen T. Sonis. (2018) Predicting mucositis risk associated with cytotoxic cancer treatment regimens: rationale, complexity, and challenges. Current Opinion in Supportive & Palliative Care 12:2, pages 198-210.
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