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Leukemia & Lymphoma Volume 59, 2018 - Issue 12
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Review

Understanding resistance mechanisms to BTK and BCL2 inhibitors in mantle cell lymphoma: implications for design of clinical trials

Rishu AgarwalDivision of Cancer Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; ;Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia;
,
Mark A. DawsonDivision of Cancer Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; ;Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia; ;Division of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; ;Centre for Cancer Research, University of Melbourne, Parkville, Victoria, Australia;
,
Martin DreylingDepartment of Medicine III, University Hospital, LMU Munich, Germany;
&
Constantine S. TamSir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia; ;Division of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; ;Department of Haematology, St Vincent's Hospital, Fitzroy, Victoria, Australia; ;Department of Medicine, University of Melbourne, Parkville, Victoria, AustraliaCorrespondence[email protected]
Pages 2769-2781 | Received 01 Feb 2018, Accepted 14 Mar 2018, Published online: 18 Jun 2018

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Clémentine Sarkozy & Vincent Ribrag. (2020) Novel agents for mantle cell lymphoma: molecular rational and clinical data. Expert Opinion on Investigational Drugs 29:6, pages 555-566.
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Dariusz Rozkiewicz, Justyna Magdalena Hermanowicz, Iwona Kwiatkowska, Anna Krupa & Dariusz Pawlak. (2023) Bruton’s Tyrosine Kinase Inhibitors (BTKIs): Review of Preclinical Studies and Evaluation of Clinical Trials. Molecules 28:5, pages 2400.
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Agnete Marie Granau, Pilar Aarøe Andersen, Theresa Jakobsen, Konstantina Taouxi, Nawar Dalila, Johanne Bay Mogensen, Lasse Sommer Kristensen, Kirsten Grønbæk & Konstantinos Dimopoulos. (2023) Concurrent Inhibition of Akt and ERK Using TIC-10 Can Overcome Venetoclax Resistance in Mantle Cell Lymphoma. Cancers 15:2, pages 510.
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Mubarak Al-Mansour. (2022) Treatment Landscape of Relapsed/Refractory Mantle Cell Lymphoma: An Updated Review. Clinical Lymphoma Myeloma and Leukemia 22:11, pages e1019-e1031.
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Shuhua Yi, Yuting Yan, Meiling Jin, Supriyo Bhattacharya, Yi Wang, Yiming Wu, Lu Yang, Eva Gine, Guillem Clot, Lu Chen, Ying Yu, Dehui Zou, Jun Wang, An T. Phan, Rui Cui, Fei Li, Qi Sun, Qiongli Zhai, Tingyu Wang, Zhen Yu, Lanting Liu, Wei Liu, Rui Lyv, Weiwei Sui, Wenyang Huang, Wenjie Xiong, Huijun Wang, Chengwen Li, Zhijian Xiao, Mu Hao, Jianxiang Wang, Tao Cheng, Silvia Bea, Alex F. Herrera, Alexey Danilov, Elias Campo, Vu N. Ngo, Lugui Qiu & Lili Wang. (2022) Genomic and transcriptomic profiling reveals distinct molecular subsets associated with outcomes in mantle cell lymphoma. Journal of Clinical Investigation 132:3.
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Bushra Tbakhi & Patrick M. Reagan. (2022) Chimeric antigen receptor (CAR) T-cell treatment for mantle cell lymphoma (MCL). Therapeutic Advances in Hematology 13, pages 204062072210807.
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Ye Zhang, Peng Lu, Yan Zhou & Lifei Zhang. (2021) Inhibition of LINK-A lncRNA overcomes ibrutinib resistance in mantle cell lymphoma by regulating Akt/Bcl2 pathway. PeerJ 9, pages e12571.
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Bin-Ru Wang, Chao-Ling Wan, Song-Bai Liu, Qiao-Cheng Qiu, Tian-Mei Wu, Jun Wang, Yan-Yan Li, Shuai-Shuai Ge, Yan Qiu, Xiang-Dong Shen, Sheng-Li Xue & Zheng Li. (2021) A Combined Histone Deacetylases Targeting Strategy to Overcome Venetoclax Plus Azacitidine Regimen Resistance in Acute Myeloid Leukaemia: Three Case Reports. Frontiers in Oncology 11.
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Carol Moreno, Cecilia Muñoz, María José Terol, José-Ángel Hernández-Rivas & Miguel Villanueva. (2021) Restoration of the immune function as a complementary strategy to treat Chronic Lymphocytic Leukemia effectively. Journal of Experimental & Clinical Cancer Research 40:1.
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D. A. Koroleva, N. G. Gabeeva, M. Yu. Drokov, V. A. Vasilyeva, B. V. Biderman, S. V. Tsygankova, E. S. Bulygina, G. M. Galstyan, A. B. Sudarikov, T. N. Obukhova, L. A. Kuzmina, E. E. Zvonkov, E. N. Parovichnikova & V. G. Savchenko. (2020) First experience of allogeneic haematopoietic stem cell transplantation in patients with mantle cell lymphoma with a mutation in the <i>TP53</i> gene. Russian journal of hematology and transfusiology 65:4, pages 483-500.
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XiaoYan Yue, Qingxiao Chen & JingSong He. (2020) Combination strategies to overcome resistance to the BCL2 inhibitor venetoclax in hematologic malignancies. Cancer Cell International 20:1.
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Gabrielle McDonald, Victor Chubukov, John Coco, Kevin Truskowski, Rohini Narayanaswamy, Sung Choe, Mya Steadman, Erin Artin, Anil K. Padyana, Lei Jin, Sebastien Ronseaux, Charles Locuson, Zi-Peng Fan, Tabea Erdmann, Alan Mann, Sebastian Hayes, Mark Fletcher, Kavitha Nellore, Siva Sanjeeva Rao, Hosahalli Subramanya, K. Satish Reddy, Sunil K. Panigrahi, Thomas Antony, Sreevalsam Gopinath, Zhihua Sui, Nelamangala Nagaraja, Lenny Dang, Georg Lenz, Jonathan Hurov, Scott A. Biller, Josh Murtie, Kevin M. Marks & Danielle B. Ulanet. (2020) Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase. Molecular Cancer Therapeutics 19:12, pages 2502-2515.
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Preetesh Jain & Michael Wang. (2019) Mantle cell lymphoma: 2019 update on the diagnosis, pathogenesis, prognostication, and management. American Journal of Hematology 94:6, pages 710-725.
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