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Leukemia & Lymphoma Volume 61, 2020 - Issue 6
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Original Articles

Interrogation of molecular profiles can help in differentiating between MDS and AML with MDS-related changes

Talha BadarDivision of Hematology and Oncology, Medical College of Wisconsin and Froedtert Hospital, Milwaukee, WI, USA; ORCID Iconhttp://orcid.org/0000-0003-1548-918X
ORCID Icon,
Aniko SzaboDivision of Hematology and Oncology, Medical College of Wisconsin and Froedtert Hospital, Milwaukee, WI, USA;
,
David SallmanDepartment of Malignant Hematology, Moffitt Cancer Center, Tampa, FL, USA;
,
Rami KomrojkiDepartment of Malignant Hematology, Moffitt Cancer Center, Tampa, FL, USA;
,
Jefferey LancetDepartment of Malignant Hematology, Moffitt Cancer Center, Tampa, FL, USA;
,
Eric PadronDepartment of Malignant Hematology, Moffitt Cancer Center, Tampa, FL, USA;
,
Jinming SongDepartment of Hematopathology and Laboratory Medicine, Moffitt Cancer Center, Tampa, FL, USAORCID Iconhttp://orcid.org/0000-0001-5642-1451
ORCID Icon &
Mohammad Omar HussainiDepartment of Hematopathology and Laboratory Medicine, Moffitt Cancer Center, Tampa, FL, USACorrespondence[email protected]
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Pages 1418-1427 | Received 17 Jul 2019, Accepted 10 Jan 2020, Published online: 04 Feb 2020

Citations (14)

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Yenny Moreno Vanegas & Talha Badar. (2022) Clinical Utility of Azacitidine in the Management of Acute Myeloid Leukemia: Update on Patient Selection and Reported Outcomes. Cancer Management and Research 14, pages 3527-3538.
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Xiaodong Lyu, Tao Li, Dandan Zhu, Yuexin Cheng, Yan Chen, Xiangxiang He, Zhenling Li, Shiyong Li, Wei Wu, Shuaipeng Geng, Mengna Zhang, Chunxiao Yao, Jingshuai Li, Yangwei Li, Yinyin Chang, Yuchun Li, Zunmin Zhu, Mao Mao & Yongping Song. (2022) Whole-genome sequencing as an alternative to analyze copy number abnormalities in acute myeloid leukemia and myelodysplastic syndrome. Leukemia & Lymphoma 63:10, pages 2301-2310.
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Talha Badar & Ehab Atallah. (2021) Do histone deacytelase inhibitors and azacitidine combination hold potential as an effective treatment for high/very-high risk myelodysplastic syndromes?. Expert Opinion on Investigational Drugs 30:6, pages 665-673.
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Qing Ching Chen & Yi-Hua Chen. (2020) Mutational profiling of myeloid neoplasms, focusing on AML with myelodysplasia-related changes (MRC) in comparison with MDS and AML without MRC. Leukemia & Lymphoma 61:6, pages 1269-1271.
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Articles from other publishers (10)

Talha Badar, Yenny A. Moreno Vanegas, Ahmad Nanaa, James M. Foran, Aref Al-Kali, Abhishek Mangaonkar, Hemant Murthy, Hassan B. Alkhateeb, David Viswanatha, Rong He, Mithun Shah, Cecilia Arana Yi, Mark R. Litzow, Naseema Gangat, Ayalew Tefferi & Mrinal M. Patnaik. (2023) U2AF1 pathogenic variants in myeloid neoplasms and precursor states: distribution of co-mutations and prognostic heterogeneity. Blood Cancer Journal 13:1.
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Naoki Kohyanagi & Takashi Ohama. (2023) The impact of SETBP1 mutations in neurological diseases and cancer . Genes to Cells.
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Davidson Zhao, Entsar Eladl, Mojgan Zarif, José‐Mario Capo‐Chichi, Andre Schuh, Eshetu Atenafu, Mark Minden & Hong Chang. (2022) Molecular characterization of AML‐MRC reveals TP53 mutation as an adverse prognostic factor irrespective of MRC ‐defining criteria, TP53 allelic state, or TP53 variant allele frequency . Cancer Medicine 12:6, pages 6511-6522.
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Xian-Fu Sheng, Li-Li Hong, Fei-Yan Huang & Hai-Feng Zhuang. (2022) Acute myeloid leukemia with myelodysplasia-related changes and blasts of the mixed T/myeloid phenotype: a case report. Journal of International Medical Research 50:9, pages 030006052211227.
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Ahmad Ghorab, Aref Al-Kali, Michelle Elliot, Naseema Gangat, Hasan Alkhateeb, Mithun Shah, Yuanhang Liu, Cecilia Arana Yi, Hemant Murthy, Mohamed Kharfan-Dabaja, Ayalew Tefferi, Mrinal Patnaik, Mark Litzow & Talha Badar. (2022) Clinical outcome of myelodysplastic syndrome progressing on hypomethylating agents with evolving frontline therapies: continued challenges and unmet needs. Blood Cancer Journal 12:6.
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Dain Kang, Jin Jung, Silvia Park, Byung-Sik Cho, Hee-Je Kim, Yeojae Kim, Jong-Mi Lee, Hoon Seok Kim, Ari Ahn, Myungshin Kim & Yonggoo Kim. (2022) Genetic Characteristics According to Subgroup of Acute Myeloid Leukemia with Myelodysplasia-Related Changes. Journal of Clinical Medicine 11:9, pages 2378.
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Katalin Kelemen. (2022) The Role of Nucleophosmin 1 (NPM1) Mutation in the Diagnosis and Management of Myeloid Neoplasms. Life 12:1, pages 109.
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James Yu, Yuan Du, Anum Jalil, Zohaib Ahmed, Shahram Mori, Rushang Patel, Juan Carlos Varela & Chung-Che Chang. (2021) Mutational profiling of myeloid neoplasms associated genes may aid the diagnosis of acute myeloid leukemia with myelodysplasia-related changes. Leukemia Research 110, pages 106701.
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Fabio Forghieri, Vincenzo Nasillo, Ambra Paolini, Francesca Bettelli, Valeria Pioli, Davide Giusti, Andrea Gilioli, Corrado Colasante, Gloria Acquaviva, Giovanni Riva, Patrizia Barozzi, Rossana Maffei, Leonardo Potenza, Roberto Marasca, Claudio Fozza, Enrico Tagliafico, Tommaso Trenti, Patrizia Comoli, Giuseppe Longo & Mario Luppi. (2020) NPM1-Mutated Myeloid Neoplasms with <20% Blasts: A Really Distinct Clinico-Pathologic Entity?. International Journal of Molecular Sciences 21:23, pages 8975.
Crossref
Daniel A Arber & Harry P Erba. (2020) Diagnosis and Treatment of Patients With Acute Myeloid Leukemia With Myelodysplasia-Related Changes (AML-MRC). American Journal of Clinical Pathology 154:6, pages 731-741.
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