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Leukemia & Lymphoma Volume 62, 2021 - Issue 1
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Original Articles

Increased myeloid-derived suppressor cells in patients with myelodysplastic syndromes suppress CD8+ T lymphocyte function through the STAT3-ARG1 pathway

Xiao Qia Department of Hematology and Oncology, Tianjin Union Medical Center of Nankai University, Tianjin, ChinaView further author information
,
Huijuan Jiangb Hematology Department, Tianjin Medical University General Hospital, Tianjin, ChinaView further author information
,
Pei Liub Hematology Department, Tianjin Medical University General Hospital, Tianjin, ChinaView further author information
,
Ning Xieb Hematology Department, Tianjin Medical University General Hospital, Tianjin, ChinaView further author information
,
Rong Fub Hematology Department, Tianjin Medical University General Hospital, Tianjin, ChinaView further author information
,
Huaquan Wangb Hematology Department, Tianjin Medical University General Hospital, Tianjin, ChinaView further author information
,
Chunyan Liub Hematology Department, Tianjin Medical University General Hospital, Tianjin, ChinaView further author information
,
Tian Zhangb Hematology Department, Tianjin Medical University General Hospital, Tianjin, ChinaView further author information
,
Huaqing Wanga Department of Hematology and Oncology, Tianjin Union Medical Center of Nankai University, Tianjin, ChinaCorrespondence[email protected]
View further author information
&
Zonghong Shaob Hematology Department, Tianjin Medical University General Hospital, Tianjin, ChinaCorrespondence[email protected]
View further author information
 show all
Pages 218-223 | Received 07 Jan 2020, Accepted 22 Aug 2020, Published online: 26 Sep 2020

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Fang Shao, Jie Pan, Yewen Xie, Jun Ding, Xiao Sun, Lei Xia, Dawei Zhu, Shizhong Wang & Chunjian Qi. Sulforaphane Attenuates AOM/DSS-Induced Colorectal Tumorigenesis in Mice via Inhibition of Intestinal Inflammation. Nutrition and Cancer 0:0, pages 1-12.
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Articles from other publishers (16)

Caroline M. Putnam, Lahari Kondeti, Meredith B. A. Kesler & Melinda E. Varney. (2023) Modulating the immune system as a therapeutic target for myelodysplastic syndromes and acute myeloid leukemia. Biochemistry and Cell Biology 101:6, pages 481-495.
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Vaishali Bhardwaj & Stephen M. Ansell. (2023) Modulation of T-cell function by myeloid-derived suppressor cells in hematological malignancies. Frontiers in Cell and Developmental Biology 11.
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Shifen Wang, Xingyun Zhao, Siwen Wu, Dawei Cui & Zhenshu Xu. (2023) Myeloid-derived suppressor cells: key immunosuppressive regulators and therapeutic targets in hematological malignancies. Biomarker Research 11:1.
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晓华 张. (2023) The Role and Research Progress of NLRP3 Inflammasome and MDSC in Myelodysplastic Syndrome. Advances in Clinical Medicine 13:03, pages 3932-3936.
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Xiaoying Zhang, Xingcheng Yang, Ling Ma, Yicheng Zhang & Jia Wei. (2023) Immune dysregulation and potential targeted therapy in myelodysplastic syndrome. Therapeutic Advances in Hematology 14.
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Likun Zheng, Lei Zhang, Yixuan Guo, Xintong Xu, Zhaoyun Liu, Zhenyu Yan & Rong Fu. (2022) The immunological role of mesenchymal stromal cells in patients with myelodysplastic syndrome. Frontiers in Immunology 13.
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Shunjie Yu, Xiaotong Ren & Lijuan Li. (2022) Myeloid-derived suppressor cells in hematologic malignancies: two sides of the same coin. Experimental Hematology & Oncology 11:1.
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Olga Kouroukli, Argiris Symeonidis, Periklis Foukas, Myrto-Kalliopi Maragkou & Eleni P. Kourea. (2022) Bone Marrow Immune Microenvironment in Myelodysplastic Syndromes. Cancers 14:22, pages 5656.
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Maria Velegraki, Andrew Stiff, Helen A. Papadaki & Zihai Li. (2022) Myeloid-Derived Suppressor Cells: New Insights into the Pathogenesis and Therapy of MDS. Journal of Clinical Medicine 11:16, pages 4908.
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Yannick Simoni & Nicolas Chapuis. (2022) Diagnosis of Myelodysplastic Syndromes: From Immunological Observations to Clinical Applications. Diagnostics 12:7, pages 1659.
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Chiara Cioccarelli & Barbara Molon. (2022) MDSCs and T cells in solid tumors and non-Hodgkin lymphomas: an immunosuppressive speech. Clinical and Experimental Immunology 208:2, pages 147-157.
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Huijuan Jiang, Xiaoyu Zhao, Mengtong Zang, Rong Fu, Zonghong Shao & Chunyan Liu. (2022) Gut Microbiome and Plasma Metabolomic Analysis in Patients with Myelodysplastic Syndrome. Oxidative Medicine and Cellular Longevity 2022, pages 1-21.
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Olivia Lynch & Laura Calvi. (2022) Immune Dysfunction, Cytokine Disruption, and Stromal Changes in Myelodysplastic Syndrome: A Review. Cells 11:3, pages 580.
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Yingying Sun, Xiaoqing Han, Chao Shang, Yawei Wang, Boya Xu, Shu Jiang, Yan Mo, Dake Wang, Yueshuang Ke & Xianlu Zeng. (2022) The downregulation of type I IFN signaling in G-MDSCs under tumor conditions promotes their development towards an immunosuppressive phenotype. Cell Death & Disease 13:1.
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Angèle Luby & Marie-Clotilde Alves-Guerra. (2021) Targeting Metabolism to Control Immune Responses in Cancer and Improve Checkpoint Blockade Immunotherapy. Cancers 13:23, pages 5912.
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Suncica Kapor & Juan F. Santibanez. (2021) Myeloid-Derived Suppressor Cells and Mesenchymal Stem/Stromal Cells in Myeloid Malignancies. Journal of Clinical Medicine 10:13, pages 2788.
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