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Leukemia & Lymphoma Volume 62, 2021 - Issue 14
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Original Articles

Clinico-genomic profiling and clonal dynamic modeling of TP53-aberrant myelodysplastic syndrome and acute myeloid leukemia

Shyam A. Patela Department of Medicine–Hematology & Oncology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8208-1902
ORCID Icon,
Maxwell R. Lloydb Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USAORCID Iconhttps://orcid.org/0000-0001-9810-0437
ORCID Icon,
Jan Cernya Department of Medicine–Hematology & Oncology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USAORCID Iconhttps://orcid.org/0000-0002-6602-5505
ORCID Icon,
Qiming Shia Department of Medicine–Hematology & Oncology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA;c Department of Population & Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA
,
Karl Simind Department of Molecular, Cell & Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA
,
Asiri Ediriwickremae Division of Hematology, Department of Medicine, Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USAORCID Iconhttps://orcid.org/0000-0002-6480-8290
ORCID Icon,
Lloyd Hutchinsonf Department of Pathology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA
,
Patricia M. Mironf Department of Pathology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA
,
Anne W. Higginsf Department of Pathology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA
,
Muthalagu Ramanathana Department of Medicine–Hematology & Oncology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA
&
Jonathan M. Gerbera Department of Medicine–Hematology & Oncology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA
 show all
Pages 3348-3360 | Received 21 Feb 2021, Accepted 13 Jul 2021, Published online: 09 Sep 2021

Citations (7)

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Read on this site (1)

Shyam A. Patel. (2023) Precision and strategic targeting of novel mutation-specific vulnerabilities in acute myeloid leukemia: the semi-centennial of 7 + 3. Leukemia & Lymphoma 64:9, pages 1503-1513.
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Articles from other publishers (6)

Claudia Bănescu, Florin Tripon & Carmen Muntean. (2023) The Genetic Landscape of Myelodysplastic Neoplasm Progression to Acute Myeloid Leukemia. International Journal of Molecular Sciences 24:6, pages 5734.
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Cui‐Zhen Liu, Jian‐Di Li, Gang Chen, Rong‐Quan He, Rui Lin, Zhi‐Guang Huang, Jian‐Jun Li, Xiu‐Fang Du & Xiao‐Ping Lv. (2022) A cohesin‐associated gene score may predict immune checkpoint blockade in hepatocellular carcinoma. FEBS Open Bio 12:10, pages 1857-1874.
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Yuxin Wang, Yao Sun, Jing Xie, Jiangwei Hu, Na Liu, Jianlin Chen, Botao Li, Sanchun Lan, Jingwen Niu, Lei Wang, Zhuoqing Qiao, Yu Zhang, Jing Ren, Bin Zhang, Liren Qian, Yehui Tan, Liping Dou, Yuhang Li & Liangding Hu. (2022) Allogeneic haematopoietic stem cell transplantation with decitabine-containing preconditioning regimen in TP53-mutant myelodysplastic syndromes: A case study. Frontiers in Oncology 12.
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Lais Ghiraldeli, Rebecca Anderson, Kristin Pladna & Timothy S. Pardee. (2022) Adenosine Monophosphate Activated Protein Kinase (AMPK) enhances chemotherapy response in Acute Myeloid Leukemia (AML). Cancer Letters 535, pages 215659.
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Shyam A. Patel. (2022) Functional genomic approaches in acute myeloid leukemia: Insights into disease models and the therapeutic potential of reprogramming. Cancer Letters 533, pages 215579.
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Shyam A. Patel & Jan Cerny. (2022) TP53 -mutant myelodysplastic syndrome and acute myeloid leukemia: the black hole of hematology . Blood Advances 6:6, pages 1917-1918.
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