248
Views
60
CrossRef citations to date
0
Altmetric
Original Article

Signal Transduction via CD44: Role of Plasma Membrane Microdomains

, &
Pages 455-469 | Published online: 30 Mar 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Adriana H Tremoulet & Salvatore Albani. (2006) Novel therapies for rheumatoid arthritis. Expert Opinion on Investigational Drugs 15:11, pages 1427-1441.
Read now
Zeineb Gadhoum, Jacques Delaunay, Eliane Maquarre, Laetitia Durand, Valérie Lancereaux, Junyuang Qi, Jacqueline Robert-Lezenes, Christine Chomienne & Florence Smadja-Joffe. (2004) The Effect of Anti-CD44 Monoclonal Antibodies on Differentiation and Proliferation of Human Acute Myeloid Leukemia Cells. Leukemia & Lymphoma 45:8, pages 1501-1510.
Read now
David Naor, Shlomo Nedvetzki, Itshak Golan, Lora Melnik & Yoram Faitelson. (2002) CD44 in Cancer. Critical Reviews in Clinical Laboratory Sciences 39:6, pages 527-579.
Read now

Articles from other publishers (57)

Qixiang Cheng, Xibo Hu, Xiaoqing Zhang, Depeng Yang, Guiping Zhao, Liping Sun, Meiyi Jiang, Lijun Yang, Jialing Cai, Bing Wang, Mengmeng Zhang, Fang Han, Yu Li & Huan Nie. (2023) N-glycosylation at N57/100/110 affects CD44s localization, function and stability in hepatocellular carcinoma. European Journal of Cell Biology 102:4, pages 151360.
Crossref
Abraham C. I. van Steen, Max L. B. Grönloh, Sander Joosten, Floris van Alphen, Maartje van den Biggelaar, Martijn A. Nolte, Marcel Spaargaren, Jaap D. van Buul & Rouven Schoppmeyer. (2023) Endothelial ICAM-1 Adhesome Recruits CD44 for Optimal Transcellular Migration of Human CTLs. The Journal of Immunology 211:3, pages 377-388.
Crossref
Shibnath Ghatak, Vincent C. Hascall, Roger R. Markwald & Suniti Misra. 2023. Hyaluronan. Hyaluronan 119 159 .
Lisa Sophie Kölln, Omar Salem, Jessica Valli, Carsten Gram Hansen & Gail McConnell. (2022) Label2label: training a neural network to selectively restore cellular structures in fluorescence microscopy. Journal of Cell Science 135:3.
Crossref
Kinga Jaskuła, Mariusz Sacharczuk, Zbigniew Gaciong & Dominik S. Skiba. (2021) Cardiovascular Effects Mediated by HMMR and CD44. Mediators of Inflammation 2021, pages 1-9.
Crossref
Bryan P. Toole. (2019) The CD147‐HYALURONAN Axis in Cancer. The Anatomical Record 303:6, pages 1573-1583.
Crossref
Hao Yang, Weitian Tian, Shaocheng Wang, Xiaohua Liu, Zhankui Wang, Lei Hou, Jiaxi Ge, Xiao Zhang, Zhengyu He & Xiangrui Wang. (2018) TSG-6 secreted by bone marrow mesenchymal stem cells attenuates intervertebral disc degeneration by inhibiting the TLR2/NF-κB signaling pathway. Laboratory Investigation 98:6, pages 755-772.
Crossref
Iris Morath, Christian Jung, Romain Lévêque, Chen Linfeng, Robert-Alain Toillon, Arne Warth & Véronique Orian-Rousseau. (2018) Differential recruitment of CD44 isoforms by ErbB ligands reveals an involvement of CD44 in breast cancer. Oncogene 37:11, pages 1472-1484.
Crossref
Jone Garay, M. Blanca Piazuelo, Sumana Majumdar, Li Li, Jimena Trillo-Tinoco, Luis Del Valle, Barbara G. Schneider, Alberto G. Delgado, Keith T. Wilson, Pelayo Correa & Jovanny Zabaleta. (2016) The homing receptor CD44 is involved in the progression of precancerous gastric lesions in patients infected with Helicobacter pylori and in development of mucous metaplasia in mice. Cancer Letters 371:1, pages 90-98.
Crossref
Hsiang-Kuang Tseng, Tseng-Yu Huang, Alice Ying-Jung Wu, Hsin-Hong Chen, Chang-Pan Liu & Ambrose Jong. (2015) How Cryptococcus interacts with the blood–brain barrier . Future Microbiology 10:10, pages 1669-1682.
Crossref
Yongmin Yan, Xiangsheng Zuo & Daoyan Wei. (2015) Concise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic Target. Stem Cells Translational Medicine 4:9, pages 1033-1043.
Crossref
Eimei SATO. (2015) Intraovarian control of selective follicular growth and induction of oocyte maturation in mammals. Proceedings of the Japan Academy, Series B 91:3, pages 76-91.
Crossref
Se Hwan Mun, Dongmyung Oh & Sun-Kyeong Lee. (2014) Macrophage Migration Inhibitory Factor Down-Regulates the RANKL-RANK Signaling Pathway by Activating Lyn Tyrosine Kinase in Mouse Models. Arthritis & Rheumatology 66:9, pages 2482-2493.
Crossref
Taigo Kato, Masayoshi Okumi, Masahiro Tanemura, Koji Yazawa, Yoichi Kakuta, Kazuaki Yamanaka, Koichi Tsutahara, Yuichiro Doki, Masaki Mori, Shiro Takahara & Norio Nonomura. (2014) Adipose Tissue-Derived Stem Cells Suppress Acute Cellular Rejection by TSG-6 and CD44 Interaction in Rat Kidney Transplantation. Transplantation 98:3, pages 277-284.
Crossref
Wenliang Zhang, Jiawei Zhao, Jen-Fu Lee, Allison Gartung, Hiba Jawadi, Wanyu Louis Lambiv, Kenneth V. Honn & Menq-Jer Lee. (2013) ETS-1-mediated Transcriptional Up-regulation of CD44 Is Required for Sphingosine-1-phosphate Receptor Subtype 3-stimulated Chemotaxis. Journal of Biological Chemistry 288:45, pages 32126-32137.
Crossref
Daniel J. Kota, Lindsey L. Wiggins, Nara Yoon & Ryang Hwa Lee. (2013) TSG-6 Produced by hMSCs Delays the Onset of Autoimmune Diabetes by Suppressing Th1 Development and Enhancing Tolerogenicity. Diabetes 62:6, pages 2048-2058.
Crossref
W. Nie & A. M. Deters. (2013) Tamarind Seed Xyloglucans Promote Proliferation and Migration of Human Skin Cells through Internalization via Stimulation of Proproliferative Signal Transduction Pathways. Dermatology Research and Practice 2013, pages 1-14.
Crossref
Valentina Audrito, Tiziana Vaisitti, Sara Serra, Cinzia Bologna, Davide Brusa, Fabio Malavasi & Silvia Deaglio. (2013) Targeting the microenvironment in chronic lymphocytic leukemia offers novel therapeutic options. Cancer Letters 328:1, pages 27-35.
Crossref
Rajesh R. Nair, Anthony W. Gebhard & Lori A. Hazlehurst. 2013. Cell Death Signaling in Cancer Biology and Treatment. Cell Death Signaling in Cancer Biology and Treatment 53 86 .
Tze -Wen Chung & Ming-Chia Yang. 2012. Stem Cells and Cancer Stem Cells, Volume 2. Stem Cells and Cancer Stem Cells, Volume 2 185 190 .
Robert Sackstein. (2011) The biology of CD44 and HCELL in hematopoiesis: the ‘step 2-bypass pathway’ and other emerging perspectives. Current Opinion in Hematology 18:4, pages 239-248.
Crossref
Biswarup Ghosh, Yan Li & Stanley A. Thayer. (2011) Inhibition of the Plasma Membrane Ca 2+ Pump by CD44 Receptor Activation of Tyrosine Kinases Increases the Action Potential Afterhyperpolarization in Sensory Neurons . The Journal of Neuroscience 31:7, pages 2361-2370.
Crossref
Undurti N. DasUndurti N. Das. 2011. Molecular Basis of Health and Disease. Molecular Basis of Health and Disease 153 173 .
Silvia Deaglio, Tiziana Vaisitti, Antonella Zucchetto, Valter Gattei & Fabio Malavasi. (2010) CD38 as a molecular compass guiding topographical decisions of chronic lymphocytic leukemia cells. Seminars in Cancer Biology 20:6, pages 416-423.
Crossref
Elisângela de Paula Silveira-Lacerda, Cesar Augusto Sam Tiago Vilanova-Costa, Flávia de Castro Pereira, Amélia Hamaguchi, Luiz Alfredo Pavanin, Luiz Ricardo Goulart, Maria Inês Homsi-Brandenburgo, Andreimar Martins Soares, Wagner Batista dos Santos & Auro Nomizo. (2009) The Ruthenium Complex cis-(Dichloro)Tetraammineruthenium(III) Chloride Presents Immune Stimulatory Activity on Human Peripheral Blood Mononuclear Cells. Biological Trace Element Research 133:3, pages 270-283.
Crossref
Ambrose Jong, Chun-Hua Wu, Gregory M. Shackleford, Kyung J. Kwon-Chung, Yun C. Chang, Han-Min Chen, Yannan Ouyang & Sheng-He Huang. (2008) Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells. Cellular Microbiology 10:6, pages 1313-1326.
Crossref
Patrick A. Singleton, Ravi Salgia, Liliana Moreno-Vinasco, Jaideep Moitra, Saad Sammani, Tamara Mirzapoiazova & Joe G.N. Garcia. (2007) CD44 Regulates Hepatocyte Growth Factor-mediated Vascular Integrity. Journal of Biological Chemistry 282:42, pages 30643-30657.
Crossref
Rachel Pakula, Aurélie Melchior, Agnès Denys, Christophe Vanpouille, Joël Mazurier & Fabrice Allain. (2007) Syndecan-1/CD147 association is essential for cyclophilin B-induced activation of p44/42 mitogen-activated protein kinases and promotion of cell adhesion and chemotaxis. Glycobiology 17:5, pages 492-503.
Crossref
Rachid Marhaba, Pia Freyschmidt-Paul & Margot Zöller. (2006) In vivoCD44-CD49d complex formation in autoimmune disease has consequences on T cell activation and apoptosis resistance. European Journal of Immunology 36:11, pages 3017-3032.
Crossref
Adriana Sumoza-Toledo, Peter G. Gillespie, Hector Romero-Ramirez, Hellen C. Ferreira-Ishikawa, Roy E. Larson & Leopoldo Santos-Argumedo. (2006) Differential localization of unconventional myosin I and nonmuscle myosin II during B cell spreading. Experimental Cell Research 312:17, pages 3312-3322.
Crossref
Claudine S. BonderStephen R. ClarkM. Ursula NormanPauline JohnsonPaul Kubes. (2006) Use of CD44 by CD4+ Th1 and Th2 lymphocytes to roll and adhere. Blood 107:12, pages 4798-4806.
Crossref
Petr Man, Petr Novák, Marek Cebecauer, Ondrej Horváth, Anna Fišerová, Vladimír Havlíček & Karel Bezouška. (2005) Mass spectrometric analysis of the glycosphingolipid‐enriched microdomains of rat natural killer cells. PROTEOMICS 5:1, pages 113-122.
Crossref
Adil I. Khan, Steven M. Kerfoot, Bryan Heit, Lixin Liu, Graciela Andonegui, Brian Ruffell, Pauline Johnson & Paul Kubes. (2004) Role of CD44 and Hyaluronan in Neutrophil Recruitment. The Journal of Immunology 173:12, pages 7594-7601.
Crossref
Kyle M. Sheehan, Lindsey B. DeLott, Richard A. West, Joy D. Bonnema & David H. DeHeer. (2004) Hyaluronic acid of high molecular weight inhibits proliferation and induces cell death in U937 macrophage cells. Life Sciences 75:26, pages 3087-3102.
Crossref
Christophe VANPOUILLE, Agnès DENYS, Mathieu CARPENTIER, Rachel PAKULA, Joël MAZURIER & Fabrice ALLAIN. (2004) Octasaccharide is the minimal length unit required for efficient binding of cyclophilin B to heparin and cell surface heparan sulphate. Biochemical Journal 382:2, pages 733-740.
Crossref
Yoonkyung Do, Prakash S. Nagarkatti & Mitzi Nagarkatti. (2004) Role of CD44 and Hyaluronic Acid (HA) in Activation of Alloreactive and Antigen-Specific T Cells by Bone Marrow-Derived Dendritic Cells. Journal of Immunotherapy 27:1, pages 1-12.
Crossref
Masaki Yokoo & Eimei Sato. 2004. 251 291 .
REGINA M. DAY & MARCELLA M. MASCARENHAS. 2004. Chemistry and Biology of Hyaluronan. Chemistry and Biology of Hyaluronan 153 188 .
WARREN KNUDSON & RICHARD S. PETERSON. 2004. Chemistry and Biology of Hyaluronan. Chemistry and Biology of Hyaluronan 83 123 .
Hector Lucero, Darren Gae & Guillermo E. Taccioli. (2003) Novel Localization of the DNA-PK Complex in Lipid Rafts. Journal of Biological Chemistry 278:24, pages 22136-22143.
Crossref
Fabrice Allain, Christophe Vanpouille, Agnès Denys, Rachel Pakula, Mathieu Carpentier & Joël Mazurier. 2003. Glycobiology and Medicine. Glycobiology and Medicine 95 106 .
Hiroshi Kobayashi, Mika Suzuki, Naohiro Kanayama, Takashi Nishida, Masaharu Takigawa & Toshihiko Terao. (2002) CD44 stimulation by fragmented hyaluronic acid induces upregulation of urokinase-type plasminogen activator and its receptor and subsequently facilitates invasion of human chondrosarcoma cells. International Journal of Cancer 102:4, pages 379-389.
Crossref
Masaki Yokoo, Yasunori Miyahayashi, Takako Naganuma, Naoko Kimura, Hiroshi Sasada & Eimei Sato. (2002) Identification of Hyaluronic Acid-Binding Proteins and Their Expressions in Porcine Cumulus-Oocyte Complexes During In Vitro Maturation1. Biology of Reproduction 67:4, pages 1165-1171.
Crossref
Paola Spessotto, Francesca Maria Rossi, Massimo Degan, Raffaele Di Francia, Roberto Perris, Alfonso Colombatti & Valter Gattei. (2002) Hyaluronan–CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9. The Journal of Cell Biology 158:6, pages 1133-1144.
Crossref
Mika Suzuki, Hiroshi Kobayashi, Naohiro Kanayama, Takashi Nishida, Masaharu Takigawa & Toshihiko Terao. (2002) CD44 stimulation by fragmented hyaluronic acid induces upregulation and tyrosine phosphorylation of c-Met receptor protein in human chondrosarcoma cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1591:1-3, pages 37-44.
Crossref
Ella Zimmerman, Benjamin Geiger & Lia Addadi. (2002) Initial Stages of Cell-Matrix Adhesion Can Be Mediated and Modulated by Cell-Surface Hyaluronan. Biophysical Journal 82:4, pages 1848-1857.
Crossref
Susan L. Kozak, Jean Michel Heard & David Kabat. (2002) Segregation of CD4 and CXCR4 into Distinct Lipid Microdomains in T Lymphocytes Suggests a Mechanism for Membrane Destabilization by Human Immunodeficiency Virus. Journal of Virology 76:4, pages 1802-1815.
Crossref
Jeff G. Leid, C.A. Speer & Mark A. Jutila. (2002) Ultrastructural examination of cytoskeletal linkage of l-selectin and comparison of l-selectin cytoskeletal association to that of other human and bovine lymphocyte surface antigens. Cellular Immunology 215:2, pages 219-231.
Crossref
M Slevin, S Kumar & J Gaffney. 2002. Hyaluronan. Hyaluronan 469 472 .
Rachida-Sihem CharradZeineb GadhoumJunyuan QiAnne GlachantMichèle AlloucheClaude JasminChristine ChomienneFlorence Smadja-Joffe. (2002) Effects of anti-CD44 monoclonal antibodies on differentiation and apoptosis of human myeloid leukemia cell lines. Blood 99:1, pages 290-299.
Crossref
Margaret A. Shipp, Ken N. Ross, Pablo Tamayo, Andrew P. Weng, Jeffery L. Kutok, Ricardo C.T. Aguiar, Michelle Gaasenbeek, Michael Angelo, Michael Reich, Geraldine S. Pinkus, Tane S. Ray, Margaret A. Koval, Kim W. Last, Andrew Norton, T. Andrew Lister, Jill Mesirov, Donna S. Neuberg, Eric S. Lander, Jon C. Aster & Todd R. Golub. (2002) Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nature Medicine 8:1, pages 68-74.
Crossref
Jerald J. Killion & Isaiah J. Fidler. 2002. Immunology for Surgeons. Immunology for Surgeons 215 230 .
Gary N. Cherr, Ashley I. Yudin & James W. Overstreet. (2001) The dual functions of GPI-anchored PH-20: hyaluronidase and intracellular signaling. Matrix Biology 20:8, pages 515-525.
Crossref
C.A. Vines, M.W. Li, X. Deng, A.I. Yudin, G.N. Cherr & J.W. Overstreet. (2001) Identification of a hyaluronic acid (HA) binding domain in the PH‐20 protein that may function in cell signaling. Molecular Reproduction and Development 60:4, pages 542-552.
Crossref
Shulamit B. Wallach-Dayan, Valentin Grabovsky, Jürgen Moll, Jonathan Sleeman, Peter Herrlich, Ronen Alon & David Naor. (2001) CD44-dependent lymphoma cell dissemination: a cell surface CD44 variant, rather than standard CD44, supports in vitro lymphoma cell rolling on hyaluronic acid substrate and its in vivo accumulation in the peripheral lymph nodes. Journal of Cell Science 114:19, pages 3463-3477.
Crossref
Szabolcs Felszeghy, László Módis, Markku Tammi & Raija Tammi. (2001) The distribution pattern of the hyaluronan receptor CD44 during human tooth development. Archives of Oral Biology 46:10, pages 939-945.
Crossref
Sara W. Feigelson, Valentin Grabovsky, Eitan Winter, Ling L. Chen, R. Blake Pepinsky, Ted Yednock, Deborah Yablonski, Roy Lobb & Ronen Alon. (2001) The Src Kinase p56 lck Up-regulates VLA-4 Integrin Affinity . Journal of Biological Chemistry 276:17, pages 13891-13901.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.