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Original

Immunolocalization of MMP-19 in the human intervertebral disc: implications for disc aging and degeneration

, Ph.D, &
Pages 157-162 | Received 13 Apr 2005, Published online: 12 Jul 2009

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Stephen M. Richardson, Anthony J. Freemont & Judith A. Hoyland. 2014. The Intervertebral Disc. The Intervertebral Disc 177 200 .
Christopher K. Kepler, Ravi K. Ponnappan, Chadi A. Tannoury, Marakand V. Risbud & David G. Anderson. (2013) The molecular basis of intervertebral disc degeneration. The Spine Journal 13:3, pages 318-330.
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Nam V. Vo, Robert A. Hartman, Takashi Yurube, Lloydine J. Jacobs, Gwendolyn A. Sowa & James D. Kang. (2013) Expression and regulation of metalloproteinases and their inhibitors in?intervertebral disc aging and degeneration. The Spine Journal 13:3, pages 331-341.
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Helen E. Gruber, Gretchen L. Hoelscher, Jane A. Ingram & Edward N. HanleyJr.Jr.. (2012) Matrix metalloproteinase-26, a novel MMP, is constitutively expressed in the human intervertebral disc in vivo and in vitro. Experimental and Molecular Pathology 92:1, pages 59-63.
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Jin Nam, Priyangi Perera, Jie Liu, Bjoern Rath, James Deschner, Robert Gassner, Timothy A. Butterfield & Sudha Agarwal. (2011) Sequential Alterations in Catabolic and Anabolic Gene Expression Parallel Pathological Changes during Progression of Monoiodoacetate-Induced Arthritis. PLoS ONE 6:9, pages e24320.
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Helen E Gruber, Jane A Ingram, Gretchen L Hoelscher, Natalia Zinchenko, H James Norton & Edward N HanleyJrJr. (2011) Constitutive expression of cathepsin K in the human intervertebral disc: new insight into disc extracellular matrix remodeling via cathepsin K and receptor activator of nuclear factor-κB ligand. Arthritis Research & Therapy 13:4.
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Y Tian, Z Peng, D Gorton, Y Xiao & N Ketheesan. (2011) Immunohistochemical analysis of structural changes in collagen for the assessment of osteoarthritis. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 225:7, pages 680-687.
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James C. latridis, Karolyn Godburn, Karin Wuertz, Mauro Alini & Peter J. Roughley. (2011) Region-Dependent Aggrecan Degradation Patterns in the Rat Intervertebral Disc Are Affected by Mechanical Loading In Vivo. Spine 36:3, pages 203-209.
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Ying Cui, Jing Yu, Jill P. G. Urban & David A. Young. (2010) Differential Gene Expression Profiling of Metalloproteinases and Their Inhibitors. Spine 35:11, pages 1101-1108.
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Helen E Gruber, Jane A Ingram, Gretchen L Hoelscher, Natalia Zinchenko, H James Norton & Edward N HanleyJrJr. (2009) Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs. Arthritis Research & Therapy 11:6.
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Beatrice E. Bachmeier, Andreas Nerlich, Norbert Mittermaier, Christoph Weiler, Christianto Lumenta, Karin Wuertz & Norbert Boos. (2009) Matrix metalloproteinase expression levels suggest distinct enzyme roles during lumbar disc herniation and degeneration. European Spine Journal 18:11, pages 1573-1586.
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Denise Freimark & Peter Czermak. (2018) Cell-Based Regeneration of Intervertebral Disc Defects: Review and Concepts. The International Journal of Artificial Organs 32:4, pages 197-203.
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Yejia Zhang, Howard S. An, Chadi Tannoury, Eugene J.-M.A. Thonar, Mitchell K. Freedman & D Greg Anderson. (2008) Biological Treatment for Degenerative Disc Disease. American Journal of Physical Medicine & Rehabilitation 87:9, pages 694-702.
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Jeffrey C. Lotz, Tamer Hadi, Clayton Bratton, Karen M. Reiser & Adam H. Hsieh. (2008) Anulus fibrosus tension inhibits degenerative structural changes in lamellar collagen. European Spine Journal 17:9, pages 1149-1159.
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Yejia Zhang, Frank M. Phillips, Eugene J.-M.A. Thonar, Theodore Oegema, Howard S. An, Jorge A. Roman-Blas, Tong-Chuan He & D Greg Anderson. (2008) Cell Therapy Using Articular Chondrocytes Overexpressing BMP-7 or BMP-10 in a Rabbit Disc Organ Culture Model. Spine 33:8, pages 831-838.
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Peter J. Roughley. 2008. Carbohydrate Chemistry, Biology and Medical Applications. Carbohydrate Chemistry, Biology and Medical Applications 133 154 .
Kalpa P. Patel, John D. Sandy, Koji Akeda, Kei Miyamoto, Takehide Chujo, Howard S. An & Koichi Masuda. (2007) Aggrecanases and Aggrecanase-generated Fragments in the Human Intervertebral Disc at Early and Advanced Stages of Disc Degeneration. Spine 32:23, pages 2596-2603.
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Chang-Qing Zhao, Li-Min Wang, Lei-Sheng Jiang & Li-Yang Dai. (2007) The cell biology of intervertebral disc aging and degeneration. Ageing Research Reviews 6:3, pages 247-261.
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